octanoic acid

octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.

Cross Reference

Introduction

To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with octanoic acid?

octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with octanoic acid

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Hemorrhage D006470 15 associated lipids
Hepatic Encephalopathy D006501 9 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Hepatorenal Syndrome D006530 1 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Hypertension, Portal D006975 12 associated lipids
Hypothyroidism D007037 32 associated lipids
Infant, Newborn, Diseases D007232 9 associated lipids
Inflammation D007249 119 associated lipids
Per page 10 20 50 100 | Total 73

PubChem Associated disorders and diseases

What pathways are associated with octanoic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with octanoic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with octanoic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with octanoic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with octanoic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with octanoic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with octanoic acid

Download all related citations
Per page 10 20 50 100 | Total 2110
Authors Title Published Journal PubMed Link
Panchal AR et al. Partitioning of pyruvate between oxidation and anaplerosis in swine hearts. 2000 Am. J. Physiol. Heart Circ. Physiol. pmid:11045976
Longnus SL et al. Regulation of myocardial fatty acid oxidation by substrate supply. 2001 Am. J. Physiol. Heart Circ. Physiol. pmid:11557544
Vincent G et al. Differential modulation of citrate synthesis and release by fatty acids in perfused working rat hearts. 2004 Am. J. Physiol. Heart Circ. Physiol. pmid:12933348
Jørgensen J and Mortensen PB Substrate utilization by intestinal mucosal tissue strips from patients with inflammatory bowel disease. 2001 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:11447021
Mizutani M et al. Localization of acyl ghrelin- and des-acyl ghrelin-immunoreactive cells in the rat stomach and their responses to intragastric pH. 2009 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:20501445
Vincent G et al. Citrate release by perfused rat hearts: a window on mitochondrial cataplerosis. 2000 Am. J. Physiol. Endocrinol. Metab. pmid:10780941
Kim JY et al. Lipid oxidation is reduced in obese human skeletal muscle. 2000 Am. J. Physiol. Endocrinol. Metab. pmid:11052958
Benthem L et al. Excess portal venous long-chain fatty acids induce syndrome X via HPA axis and sympathetic activation. 2000 Am. J. Physiol. Endocrinol. Metab. pmid:11093916
Bezaire V et al. Identification of fatty acid translocase on human skeletal muscle mitochondrial membranes: essential role in fatty acid oxidation. 2006 Am. J. Physiol. Endocrinol. Metab. pmid:16219667
Cha BS et al. Impaired fatty acid metabolism in type 2 diabetic skeletal muscle cells is reversed by PPARgamma agonists. 2005 Am. J. Physiol. Endocrinol. Metab. pmid:15727952
Sakata I et al. Colocalization of ghrelin O-acyltransferase and ghrelin in gastric mucosal cells. 2009 Am. J. Physiol. Endocrinol. Metab. pmid:19401456
Tham E et al. Acylated ghrelin concentrations are markedly decreased during pregnancy in mothers with and without gestational diabetes: relationship with cholinesterase. 2009 Am. J. Physiol. Endocrinol. Metab. pmid:19240252
Hommelberg PP et al. Fatty acid-induced NF-kappaB activation and insulin resistance in skeletal muscle are chain length dependent. 2009 Am. J. Physiol. Endocrinol. Metab. pmid:18957619
Bando M et al. Transgenic overexpression of intraislet ghrelin does not affect insulin secretion or glucose metabolism in vivo. 2012 Am. J. Physiol. Endocrinol. Metab. pmid:22114024
Turcotte LP et al. High carbohydrate availability increases LCFA uptake and decreases LCFA oxidation in perfused muscle. 2002 Am. J. Physiol. Endocrinol. Metab. pmid:11739099
Miller TB Cardiac performance of isolated perfused hearts from alloxan diabetic rats. 1979 Am. J. Physiol. pmid:443443
Lemieux G et al. Glutamine synthetase and glutamyltransferase in the kidney of man, dog, and rat. 1976 Am. J. Physiol. pmid:10736
Sidossis LS et al. Regulation of fatty acid oxidation in untrained vs. trained men during exercise. 1998 Am. J. Physiol. pmid:9530135
Morand C et al. Fatty acids are potent modulators of lactate utilization in isolated hepatocytes from fed rats. 1993 Am. J. Physiol. pmid:8498503
Tanner GA et al. Excretion of phenol red by the Necturus kidney. 1979 Am. J. Physiol. pmid:443381