octanoic acid

octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.

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Introduction

To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with octanoic acid?

octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with octanoic acid

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Hemorrhage D006470 15 associated lipids
Hepatic Encephalopathy D006501 9 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Hepatorenal Syndrome D006530 1 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Hypertension, Portal D006975 12 associated lipids
Hypothyroidism D007037 32 associated lipids
Infant, Newborn, Diseases D007232 9 associated lipids
Inflammation D007249 119 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with octanoic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with octanoic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with octanoic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with octanoic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with octanoic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with octanoic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with octanoic acid

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Authors Title Published Journal PubMed Link
Parshintsev J et al. Desorption atmospheric pressure photoionization high-resolution mass spectrometry: a complementary approach for the chemical analysis of atmospheric aerosols. 2015 Rapid Commun. Mass Spectrom. pmid:26395607
Wang L et al. Octanoylated ghrelin attenuates angiogenesis induced by oxLDL in human coronary artery endothelial cells via the GHSR1a-mediated NF-κB pathway. 2015 Metab. Clin. Exp. pmid:26277200
Kim SA and Rhee MS Predictive model and optimization of a combined treatment of caprylic acid and citric acid for the reduction of Escherichia coli O157:H7 using the response surface methodology. 2015 Int. J. Food Microbiol. pmid:25544642
Vargas M et al. Human plasma-derived immunoglobulin G fractionated by an aqueous two-phase system, caprylic acid precipitation, and membrane chromatography has a high purity level and is free of detectable in vitro thrombogenic activity. 2015 Vox Sang. pmid:25469648
Socała K et al. Role of the adenosine system and glucose restriction in the acute anticonvulsant effect of caprylic acid in the 6 Hz psychomotor seizure test in mice. 2015 Prog. Neuropsychopharmacol. Biol. Psychiatry pmid:25455587
Wlaź P et al. Acute anticonvulsant effects of capric acid in seizure tests in mice. 2015 Prog. Neuropsychopharmacol. Biol. Psychiatry pmid:25445478
Skřivanová E et al. Potential use of caprylic acid in broiler chickens: effect on Salmonella enteritidis. 2015 Foodborne Pathog. Dis. pmid:25407657
Goodwin D et al. Stability, permeability and growth-inhibitory properties of gonadotropin-releasing hormone liposaccharides. 2015 Pharm. Res. pmid:25407542
Narayanan A et al. Anticarcinogenic properties of medium chain fatty acids on human colorectal, skin and breast cancer cells in vitro. 2015 Int J Mol Sci pmid:25749477
Borrull A et al. New insights into the toxicity mechanism of octanoic and decanoic acids on Saccharomyces cerevisiae. 2015 Yeast pmid:25773463
Sengupta A et al. Production of medium chain fatty acid rich mustard oil using packed bed bioreactor. 2015 J Oleo Sci pmid:25748375
El-Ekiaby M et al. Minipool caprylic acid fractionation of plasma using disposable equipment: a practical method to enhance immunoglobulin supply in developing countries. 2015 PLoS Negl Trop Dis pmid:25719558
Xu J et al. Dual receptor-targeting ⁹⁹mTc-labeled Arg-Gly-Asp-conjugated Alpha-Melanocyte stimulating hormone hybrid peptides for human melanoma imaging. 2015 Nucl. Med. Biol. pmid:25577037
Rosenblatt J et al. Caprylic acid and glyceryl trinitrate combination for eradication of biofilm. 2015 Antimicrob. Agents Chemother. pmid:25534725
Gourcerol G et al. Impaired fasting pyloric compliance in gastroparesis and the therapeutic response to pyloric dilatation. 2015 Aliment. Pharmacol. Ther. pmid:25523288
Nass R et al. The level of circulating octanoate does not predict ghrelin O-acyl transferase (GOAT)-mediated acylation of ghrelin during fasting. 2015 J. Clin. Endocrinol. Metab. pmid:25337923
Chang P et al. Seizure control by derivatives of medium chain fatty acids associated with the ketogenic diet show novel branching-point structure for enhanced potency. 2015 J. Pharmacol. Exp. Ther. pmid:25326131
Nakajima K et al. Triterpenes suppress octanoylated ghrelin production in ghrelin-expressing human gastric carcinoma cells. 2016 Biomed. Res. pmid:28003581
Hogan S et al. Eradication of Staphylococcus aureus Catheter-Related Biofilm Infections Using ML:8 and Citrox. 2016 Antimicrob. Agents Chemother. pmid:27458213
Lockman KA et al. Proteomic profiling of cellular steatosis with concomitant oxidative stress in vitro. 2016 Lipids Health Dis pmid:27368608