octanoic acid

octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.

Cross Reference

Introduction

To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with octanoic acid?

octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with octanoic acid

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Hemorrhage D006470 15 associated lipids
Hepatic Encephalopathy D006501 9 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Hepatorenal Syndrome D006530 1 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Hypertension, Portal D006975 12 associated lipids
Hypothyroidism D007037 32 associated lipids
Infant, Newborn, Diseases D007232 9 associated lipids
Inflammation D007249 119 associated lipids
Per page 10 20 50 100 | Total 73

PubChem Associated disorders and diseases

What pathways are associated with octanoic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with octanoic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with octanoic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with octanoic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with octanoic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with octanoic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with octanoic acid

Download all related citations
Per page 10 20 50 100 | Total 2110
Authors Title Published Journal PubMed Link
Pulkkinen L et al. Ghrelin in diabetes and metabolic syndrome. 2010 Int J Pept pmid:20700400
Schwandt SE et al. Differential roles for octanoylated and decanoylated ghrelins in regulating appetite and metabolism. 2010 Int J Pept pmid:20700399
Foschi D et al. Treatment of morbid obesity by intraparietogastric administration of botulinum toxin: a randomized, double-blind, controlled study. 2007 Int J Obes (Lond) pmid:17006442
Davaran S et al. Adriamycin release from poly(lactide-coglycolide)-polyethylene glycol nanoparticles: synthesis, and in vitro characterization. 2006 Int J Nanomedicine pmid:17722284
Li D et al. In vitro evaluation of anticancer nanomedicines based on doxorubicin and amphiphilic Y-shaped copolymers. 2012 Int J Nanomedicine pmid:22701317
Meyer H et al. Lipidic nanocapsule drug delivery: neuronal protection for cochlear implant optimization. 2012 Int J Nanomedicine pmid:22654517
Shi S et al. Self-assembled mPEG-PCL-g-PEI micelles for simultaneous codelivery of chemotherapeutic drugs and DNA: synthesis and characterization in vitro. 2012 Int J Nanomedicine pmid:22619525
Akbarzadeh A et al. Preparation and in vitro evaluation of doxorubicin-loaded Fe₃O₄ magnetic nanoparticles modified with biocompatible copolymers. 2012 Int J Nanomedicine pmid:22334781
Ma Y et al. Novel docetaxel-loaded nanoparticles based on PCL-Tween 80 copolymer for cancer treatment. 2011 Int J Nanomedicine pmid:22114498
Feng L et al. Development and optimization of oil-filled lipid nanoparticles containing docetaxel conjugates designed to control the drug release rate in vitro and in vivo. 2011 Int J Nanomedicine pmid:22072889
Guo QF et al. Synthesis and properties of a novel biodegradable poly(ester amine) copolymer based on poly(L-lactide) and low molecular weight polyethylenimine for gene delivery. 2011 Int J Nanomedicine pmid:21904454
Garro AG et al. Reversible exposure of hydrophobic residues on albumin as a novel strategy for formulation of nanodelivery vehicles for taxanes. 2011 Int J Nanomedicine pmid:21822381
de Azevedo Mde B et al. New formulation of an old drug in hypertension treatment: the sustained release of captopril from cyclodextrin nanoparticles. 2011 Int J Nanomedicine pmid:21720512
Cao J et al. Synthesis of a novel biodegradable polyurethane with phosphatidylcholines. 2010 Int J Mol Sci pmid:20480047
Feng Y and Guo J Biodegradable polydepsipeptides. 2009 Int J Mol Sci pmid:19333423
Zarevúcka M and Wimmer Z Plant products for pharmacology: application of enzymes in their transformations. 2008 Int J Mol Sci pmid:19330086
Narayanan A et al. Anticarcinogenic properties of medium chain fatty acids on human colorectal, skin and breast cancer cells in vitro. 2015 Int J Mol Sci pmid:25749477
Kuo CH et al. High yield of wax ester synthesized from cetyl alcohol and octanoic acid by lipozyme RMIM and Novozym 435. 2012 Int J Mol Sci pmid:23109878
Abdolmohammadi S et al. Enhancement of mechanical and thermal properties of polycaprolactone/chitosan blend by calcium carbonate nanoparticles. 2012 Int J Mol Sci pmid:22605993
Du J et al. Biodegradable nanoparticles of mPEG-PLGA-PLL triblock copolymers as novel non-viral vectors for improving siRNA delivery and gene silencing. 2012 Int J Mol Sci pmid:22312268
Lan D et al. Optimal production and biochemical properties of a lipase from Candida albicans. 2011 Int J Mol Sci pmid:22072943
Calzadilla P et al. N-acetylcysteine reduces markers of differentiation in 3T3-L1 adipocytes. 2011 Int J Mol Sci pmid:22072928
Cheng YY et al. A novel cold-adapted lipase from Sorangium cellulosum strain So0157-2: gene cloning, expression, and enzymatic characterization. 2011 Int J Mol Sci pmid:22072918
de Oliveira AL et al. Adrenergic metabolic and hemodynamic effects of octopamine in the liver. 2013 Int J Mol Sci pmid:24196353
Lan DM et al. A novel cold-active lipase from Candida albicans: cloning, expression and characterization of the recombinant enzyme. 2011 Int J Mol Sci pmid:21747717
Ahmadzadeh N et al. Production and characterization of liquid-stored and lyophilized reconstituted human infusible platelet membranes. 2011 Int J Lab Hematol pmid:21707938
Gasco MR et al. In vitro release of propranolol from oil/water microemuisions. 1988 Int J Cosmet Sci pmid:19456940
Lipik VT and Abadie MJ Synthesis of Block Copolymers of Varying Architecture Through Suppression of Transesterification during Coordinated Anionic Ring Opening Polymerization. 2012 Int J Biomater pmid:22844286
Faria M et al. Surface Characterization of Asymmetric Bi-Soft Segment Poly(ester urethane urea) Membranes for Blood-Oxygenation Medical Devices. 2012 Int J Biomater pmid:22164163
Aydin HM et al. Attachment and growth of fibroblasts on poly(L-lactide/epsilon-caprolactone) scaffolds prepared in supercritical CO2 and modified by polyethylene imine grafting with ethylene diamine-plasma in a glow-discharge apparatus. 2006 Int J Artif Organs pmid:17033995
Zea L et al. Chromatography-olfactometry study of the aroma of fino sherry wines. 2010 Int J Anal Chem pmid:20689702
Peyser RD et al. Analysis of cytochrome P450 contribution to evolved plant toxin resistance in Drosophila sechellia. 2017 Insect Mol. Biol. pmid:28703934
Kamita SG et al. Juvenile hormone (JH) esterase: why are you so JH specific? 2003 Insect Biochem. Mol. Biol. pmid:14599498
Tong LH et al. Pentasubstituted ferrocene and dirhodium(II) tetracarboxylate as building blocks for discrete fullerene-like and extended supramolecular structures. 2011 Inorg Chem pmid:21314191
Falber A et al. Routes to new hafnium(IV) tetraaryl porphyrins and crystal structures of unusual phosphate-, sulfate-, and peroxide-bridged dimers. 2008 Inorg Chem pmid:18088113
Stepanenko IN et al. Conjugation of organoruthenium(II) 3-(1H-benzimidazol-2-yl)pyrazolo[3,4-b]pyridines and indolo[3,2-d]benzazepines to recombinant human serum albumin: a strategy to enhance cytotoxicity in cancer cells. 2011 Inorg Chem pmid:22111668
Dengler T et al. Quantitative determination of sodium-octanoate in human serum albumin preparations. 1988 Infusionstherapie pmid:3235205
Carr C and Morrison DC Mechanism of polymyxin B-mediated lysis of lipopolysaccharide-treated erythrocytes. 1985 Infect. Immun. pmid:2989182
Miura S et al. Increased proliferative response of lymphocytes from intestinal lymph during long chain fatty acid absorption. 1993 Immunology pmid:8436400
Elluru S et al. Comparative study of the anti-inflammatory effect of two intravenous immunoglobulin preparations manufactured by different processes. 2006 Immunol. Lett. pmid:16952403
Hara Y et al. Exposure to fatty acids modulates interferon production by intraepithelial lymphocytes. 2003 Immunol. Lett. pmid:12644315
Grekin RJ et al. Pressor effects of portal venous oleate infusion. A proposed mechanism for obesity hypertension. 1995 Hypertension pmid:7607723
Temponi M et al. Purification of murine IgG monoclonal antibodies by precipitation with caprylic acid: comparison with other methods of purification. 1989 Hybridoma pmid:2784406
Ashwood-Smith MJ et al. The use of Albuminar 5 as a medium supplement in clinical IVF. 1989 Hum. Reprod. pmid:2778056
Boles RG et al. Biochemical diagnosis of fatty acid oxidation disorders by metabolite analysis of postmortem liver. 1994 Hum. Pathol. pmid:8056418
Liu X et al. [One simple and efficient method for purification of IgG McAb from mice ascites: caprylic acid/ammonium sulfate precipitation]. 1999 Hua Xi Yi Ke Da Xue Xue Bao pmid:11387969
Kojima M et al. Purification and distribution of ghrelin: the natural endogenous ligand for the growth hormone secretagogue receptor. 2001 Horm. Res. pmid:11786694
Berne C The effect of fatty acids and ketone bodies on the biosynthesis of insulin in isolated pancreatic islets of obese hyperglycemic mice. 1975 Horm. Metab. Res. pmid:1102408
Geelen MJ and Schmitz MG The role of citrate in the regulation of hepatic fatty acid synthesis by insulin and glucagon. 1993 Horm. Metab. Res. pmid:7903266
Chen V et al. Regulation of substrate oxidation in isolated myocardial cells by beta-hydroxybutyrate. 1984 Horm. Metab. Res. pmid:6735347
Barth CA et al. Morphology and metabolism of adult rat hepatocytes in primary culture. 1980 Hoppe-Seyler's Z. Physiol. Chem. pmid:6997170
Desjardins CA et al. The genetic basis of interspecies host preference differences in the model parasitoid Nasonia. 2010 Heredity (Edinb) pmid:20087393
Amlou M et al. Larval tolerance in the Drosophila melanogaster species complex toward the two toxic acids of the D. sechellia host plant. 1998 Hereditas pmid:9868925
Zeneroli ML et al. Visual evoked potentials in encephalopathy induced by galactosamine, ammonia, dimethyldisulfide, and octanoic acid. 1982 Sep-Oct Hepatology pmid:7118066
Zieve L et al. Ammonia, octanoate and a mercaptan depress regeneration of normal rat liver after partial hepatectomy. 1985 Jan-Feb Hepatology pmid:3967863
Walden HR et al. Xenobiotic incorporation into pyruvate dehydrogenase complex can occur via the exogenous lipoylation pathway. 2008 Hepatology pmid:19003917
Butterworth RF Pathophysiology of hepatic encephalopathy: The concept of synergism. 2008 Hepatol. Res. pmid:19125942
Vignolo MC et al. Gastric emptying before and after cholecystectomy in patients with cholecystolithiasis. 2008 May-Jun Hepatogastroenterology pmid:18705281
Ebara S et al. The relationship between gastric emptying determined by the breath test and H. pylori. 2007 Hepatogastroenterology pmid:17523334
Anti M et al. Effects of mineral-water supplementation on gastric emptying of solids in patients with functional dyspepsia assessed with the 13C-octanoic-acid breath test. 2004 Nov-Dec Hepatogastroenterology pmid:15532843
Mawatari H et al. The continuous real-time 13C-octanoate breath test for patients with nonalcoholic steatohepatitis using the BreathID system. 2009 Sep-Oct Hepatogastroenterology pmid:19950806
Ewenstein BM and Reininger AJ Re: low incidence of factor VIII inhibitors in PUPs during prophylaxis, on-demand treatment and surgical procedures, with Octanate®: interim report from an ongoing prospective clinical study. 2011 Haemophilia pmid:21752157
Klukowska A et al. Low incidence of factor VIII inhibitors in previously untreated patients during prophylaxis, on-demand treatment and surgical procedures, with Octanate®: interim report from an ongoing prospective clinical study. 2011 Haemophilia pmid:21118334
Borlace GN et al. Helicobacter pylori phagosome maturation in primary human macrophages. 2011 Gut Pathog pmid:21426584
Masaoka T and Tack J Gastroparesis: current concepts and management. 2009 Gut Liver pmid:20431741
De Silva A and Bloom SR Gut Hormones and Appetite Control: A Focus on PYY and GLP-1 as Therapeutic Targets in Obesity. 2012 Gut Liver pmid:22375166
Talley NJ et al. Effects of a motilin receptor agonist (ABT-229) on upper gastrointestinal symptoms in type 1 diabetes mellitus: a randomised, double blind, placebo controlled trial. 2001 Gut pmid:11511562
Richardson A et al. Short chain fatty acids in the terminal ileum accelerate stomach to caecum transit time in the rat. 1991 Gut pmid:2013421
Jørgensen JR et al. Absorption and metabolism of octanoate by the rat colon in vivo: concentration dependency and influence of alternative fuels. 2002 Gut pmid:12077096
De Preter V et al. Faecal metabolite profiling identifies medium-chain fatty acids as discriminating compounds in IBD. 2015 Gut pmid:24811995
Min R et al. [Investigation on low power microwave irradiation-assisted enzymatic esterification in organic solvent by fluorescence spectroscopy]. 2009 Guang Pu Xue Yu Guang Pu Fen Xi pmid:19445220
Eanes WF et al. Targeted selection experiments and enzyme polymorphism: negative evidence for octanoate selection at the G6PD locus in Drosophila melanogaster. 1985 Genetics pmid:3918918
Jones CD The genetic basis of Drosophila sechellia's resistance to a host plant toxin. 1998 Genetics pmid:9691045
Hungate EA et al. A locus in Drosophila sechellia affecting tolerance of a host plant toxin. 2013 Genetics pmid:24037270
Bijlsma R and Kerver JW The effect of DDT on the polymorphism at the G6pd and Pgd loci in Drosophila melanogaster. 1983 Genetics pmid:6404694
Jones CD The genetic basis of larval resistance to a host plant toxin in Drosophila sechellia. 2001 Genet. Res. pmid:11865712
Kössler F and Nasledov GA Effects of Na-octanoate on potassium contractures in normal and denervated frog tonic fibres. 1986 Gen. Physiol. Biophys. pmid:2433184
Pappas SC et al. Visual evoked potentials in a rabbit model of hepatic encephalopathy. II. Comparison of hyperammonemic encephalopathy, postictal coma, and coma induced by synergistic neurotoxins. 1984 Gastroenterology pmid:6693016
Moechars D et al. Altered gastrointestinal and metabolic function in the GPR39-obestatin receptor-knockout mouse. 2006 Gastroenterology pmid:17030183
Jensen GL et al. Dietary modification of chyle composition in chylothorax. 1989 Gastroenterology pmid:2502466
Cole SG et al. Cholesteryl octanoate breath test. Preliminary studies on a new noninvasive test of human pancreatic exocrine function. 1987 Gastroenterology pmid:3678753
Choi MG et al. [13C]octanoic acid breath test for gastric emptying of solids: accuracy, reproducibility, and comparison with scintigraphy. 1997 Gastroenterology pmid:9097998
Maes BD et al. 13C-Octanoic acid breath test for gastric emptying rate of solids. 1998 Gastroenterology pmid:9547107
Perri F et al. 13C-Octanoic acid breath test: valueless test for gastric emptying? 1998 Gastroenterology pmid:9547108
Ghoos YF et al. Measurement of gastric emptying rate of solids by means of a carbon-labeled octanoic acid breath test. 1993 Gastroenterology pmid:8500721
Thumshirn M et al. Modulation of gastric sensory and motor functions by nitrergic and alpha2-adrenergic agents in humans. 1999 Gastroenterology pmid:10029616
Dobbins JW and Binder HJ Effect of bile salts and fatty acids on the colonic absorption of oxalate. 1976 Gastroenterology pmid:1269869
Lamabadusuriya SP et al. Influence of mixtures of taurocholate, fatty acids, and monolein on the toxic effects of deoxycholate in rat jejunum in vivo. 1975 Gastroenterology pmid:125213
Mion F et al. (13)CO(2) breath tests: comparison of isotope ratio mass spectrometry and non-dispersive infrared spectrometry results. 2001 Gastroenterol. Clin. Biol. pmid:11449126
Nau H and Löscher W Pharmacologic evaluation of various metabolites and analogs of valproic acid: teratogenic potencies in mice. 1986 Fundam Appl Toxicol pmid:3086174
Rolls ET Chemosensory learning in the cortex. 2011 Front Syst Neurosci pmid:21954379
Golbidi S et al. Diabetes and alpha lipoic Acid. 2011 Front Pharmacol pmid:22125537
Little TJ and Feinle-Bisset C Oral and gastrointestinal sensing of dietary fat and appetite regulation in humans: modification by diet and obesity. 2010 Front Neurosci pmid:21088697
Han N et al. Hydrogel-electrospun fiber mat composite coatings for neural prostheses. 2011 Front Neuroeng pmid:21441993
Duarte JM et al. Compartmentalized Cerebral Metabolism of [1,6-(13)C]Glucose Determined by in vivo (13)C NMR Spectroscopy at 14.1 T. 2011 Front Neuroenergetics pmid:21713114
Frago LM et al. Neuroprotective actions of ghrelin and growth hormone secretagogues. 2011 Front Mol Neurosci pmid:21994488
Kaiya H et al. Ghrelin Receptor in Two Species of Anuran Amphibian, Bullfrog (Rana catesbeiana), and Japanese Tree Frog (Hyla japonica). 2011 Front Endocrinol (Lausanne) pmid:22654801
Alva-Murillo N et al. Sodium Octanoate Modulates the Innate Immune Response of Bovine Mammary Epithelial Cells through the TLR2/P38/JNK/ERK1/2 Pathway: Implications during Staphylococcus aureus Internalization. 2017 Front Cell Infect Microbiol pmid:28361042
Sen CK et al. Regulation of cellular thiols in human lymphocytes by alpha-lipoic acid: a flow cytometric analysis. 1997 Free Radic. Biol. Med. pmid:9098099
Lavieri NA et al. Investigating the control of Listeria monocytogenes on a ready-to-eat ham product using natural antimicrobial ingredients and postlethality interventions. 2014 Foodborne Pathog. Dis. pmid:24824223