octanoic acid

octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.

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Introduction

To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with octanoic acid?

octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with octanoic acid

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Hemorrhage D006470 15 associated lipids
Hepatic Encephalopathy D006501 9 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Hepatorenal Syndrome D006530 1 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Hypertension, Portal D006975 12 associated lipids
Hypothyroidism D007037 32 associated lipids
Infant, Newborn, Diseases D007232 9 associated lipids
Inflammation D007249 119 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with octanoic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with octanoic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with octanoic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with octanoic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with octanoic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with octanoic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with octanoic acid

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Authors Title Published Journal PubMed Link
Sogorb MA et al. Hydrolysis of carbaryl by human serum albumin. 2004 Arch. Toxicol. pmid:15235763
Baraldi M et al. Toxins in hepatic encephalopathy: the role of the synergistic effect of ammonia, mercaptans and short chain fatty acids. 1984 Arch. Toxicol. Suppl. pmid:6097201
Kawamoto T et al. Anti-T cell immunoglobulin and mucin domain-2 monoclonal antibody exacerbates collagen-induced arthritis by stimulating B cells. 2011 Arthritis Res. Ther. pmid:21426565
Dieterle F et al. Urinary nucleosides as potential tumor markers evaluated by learning vector quantization. 2003 Artif Intell Med pmid:12927336
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Riehle M and Bereiter-Hahn J Ouabain and digitoxin as modulators of chick embryo cardiomyocyte energy metabolism. 1994 Arzneimittelforschung pmid:7945537
Wang X et al. A self-contained 48-well fatty acid oxidation assay. 2004 Assay Drug Dev Technol pmid:15090211
Rücker W et al. Antiatherosclerotic and antihyperlipidemic effects of octimibate sodium in rabbits. 1988 Atherosclerosis pmid:3348838
Allen PC Physiological responses of chicken gut tissue to infection with Eimeria acervulina. 1984 Oct-Dec Avian Dis. pmid:6441557
Allen PC The effect of Eimeria acervulina infection on hearts of young broiler chicks. 1987 Jul-Sep Avian Dis. pmid:3675428
Mathiesen L et al. Transport of benzo[alpha]pyrene in the dually perfused human placenta perfusion model: effect of albumin in the perfusion medium. 2009 Basic Clin. Pharmacol. Toxicol. pmid:19508462
Rösen P et al. Myocardial performance and metabolism in non-ketotic, diabetic rat hearts: myocardial function and metabolism in vivo and in the isolated perfused heart under the influence of insulin and octanoate. 1986 Nov-Dec Basic Res. Cardiol. pmid:3545178
Cave AC et al. A model of anoxic preconditioning in the isolated rat cardiac myocyte. Importance of adenosine and insulin. 1996 May-Jun Basic Res. Cardiol. pmid:8831940
Amlou M et al. Genetic analysis of Drosophila sechellia specialization: oviposition behavior toward the major aliphatic acids of its host plant. 1998 Behav. Genet. pmid:9926614
Wang Z and Zhang Q [Study on pulmonary delivery system of salmon calcitonin in rats]. 2003 Beijing Da Xue Xue Bao pmid:12914259
Böhles H et al. The influence of i.v. MCT and carnitine on the excretion of dicarboxylic acids. 1988 Beitr Infusionther Klin Ernahr pmid:3132147
Lee SM et al. Prevention of the metabolic effects of 2-tetradecylglycidate by octanoic acid in the genetically diabetic mouse (db/db). 1985 Biochem Med pmid:3994695
Lutz WH et al. Inhibition of citrulline synthesis by octanoate and its modulation by adenine nucleotides. 1985 Biochem Med pmid:4052056
Bjorge SM and Baillie TA Inhibition of medium-chain fatty acid beta-oxidation in vitro by valproic acid and its unsaturated metabolite, 2-n-propyl-4-pentenoic acid. 1985 Biochem. Biophys. Res. Commun. pmid:3933498
Shanado Y et al. Lysophospholipase I identified as a ghrelin deacylation enzyme in rat stomach. 2004 Biochem. Biophys. Res. Commun. pmid:15555596