octanoic acid

octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.

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Introduction

To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with octanoic acid?

octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with octanoic acid

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Hemorrhage D006470 15 associated lipids
Hepatic Encephalopathy D006501 9 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Hepatorenal Syndrome D006530 1 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Hypertension, Portal D006975 12 associated lipids
Hypothyroidism D007037 32 associated lipids
Infant, Newborn, Diseases D007232 9 associated lipids
Inflammation D007249 119 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with octanoic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with octanoic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with octanoic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with octanoic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with octanoic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with octanoic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with octanoic acid

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Authors Title Published Journal PubMed Link
Miura T et al. Purification and properties of ghrelin from the intestine of the goldfish, Carassius auratus. 2009 Peptides pmid:19150635
Kojima M and Kangawa K The discovery of ghrelin: with a little luck and great passion. Preface. 2011 Peptides pmid:22027335
Wang J et al. Pharmacokinetics, toxicity of nasal cilia and immunomodulating effects in Sprague-Dawley rats following intranasal delivery of thymopentin with or without absorption enhancers. 2006 Peptides pmid:16242213
Sulkers EJ et al. Quantitation of oxidation of medium-chain triglycerides in preterm infants. 1989 Pediatr. Res. pmid:2797943
Jones PM et al. Accumulation of 3-hydroxy-fatty acids in the culture medium of long-chain L-3-hydroxyacyl CoA dehydrogenase (LCHAD) and mitochondrial trifunctional protein-deficient skin fibroblasts: implications for medium chain triglyceride dietary treatment of LCHAD deficiency. 2003 Pediatr. Res. pmid:12621125
Trauner DA and Adams H Intracranial pressure elevations during octanoate infusion in rabbits: an experimental model of Reye's syndrome. 1981 Pediatr. Res. pmid:7267183
Nakajima T et al. The effect of carnitine on ketogenesis in perfused livers from juvenile visceral steatosis mice with systemic carnitine deficiency. 1997 Pediatr. Res. pmid:9212045
Whyte RK et al. Excretion of dicarboxylic and omega-1 hydroxy fatty acids by low birth weight infants fed with medium-chain triglycerides. 1986 Pediatr. Res. pmid:3080726
Trauner DA Regional cerebral Na+K+ ATPase activity following octanoate administration. 1980 Pediatr. Res. pmid:6250122
Yoshida Y et al. Effect of salicylic acid on mitochondrial-peroxisomal fatty acid catabolism. 1988 Pediatr. Res. pmid:3353181
Roe CR et al. Diagnostic and therapeutic implications of medium-chain acylcarnitines in the medium-chain acyl-coA dehydrogenase deficiency. 1985 Pediatr. Res. pmid:4000772
Dombrowski GJ and Swiatek KR Lactate genesis by rat liver and muscle during development. 1991 Pediatr. Res. pmid:1956716
Trauner DA and Garrett RS Effect of octanoate injection on rat blood-brain barrier. 1985 Jan-Feb Pediatr. Neurol. pmid:3880386
Trauner DA and de la Torre JC Effect of octanoate on blood-brain barrier permeability using L-dopa as a marker. 1985 Jul-Aug Pediatr. Neurol. pmid:3880408
Trice JE and Trauner DA Alterations in serum glucose and hepatic glycogen concentrations during octanoate administration in rabbits. 1985 Sep-Oct Pediatr. Neurol. pmid:3880415
Trauner DA and Adams HR Effects of therapeutic agents in a rabbit model of Reye syndrome. 1987 May-Jun Pediatr. Neurol. pmid:3508061
Massaldi H and Morais V Evolution of endotoxin contamination during production of a therapeutic serum. 2007 Sep-Oct PDA J Pharm Sci Technol pmid:18047176
Tezikov EB et al. [Effect of beta-hydroxybutyrate and caprylic acid on function of isolated rat heart in alcoholic intoxication and in the post-intoxication period]. 1993 May-Jun Patol Fiziol Eksp Ter pmid:8058394
Müller T Levodopa/carbidopa and entacapone in the treatment of Parkinson's disease: efficacy, safety and patient preference. 2009 Patient Prefer Adherence pmid:19936145
Webb T Identification of interference affecting the gas-liquid chromatography analysis of valproic acid in quality control material. 1986 Pathology pmid:3097616