octanoic acid

octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.

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Introduction

To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with octanoic acid?

octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with octanoic acid

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Hemorrhage D006470 15 associated lipids
Hepatic Encephalopathy D006501 9 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Hepatorenal Syndrome D006530 1 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Hypertension, Portal D006975 12 associated lipids
Hypothyroidism D007037 32 associated lipids
Infant, Newborn, Diseases D007232 9 associated lipids
Inflammation D007249 119 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with octanoic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with octanoic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with octanoic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with octanoic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with octanoic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with octanoic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with octanoic acid

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Authors Title Published Journal PubMed Link
de Assis DR et al. Evidence that antioxidants prevent the inhibition of Na+,K(+)-ATPase activity induced by octanoic acid in rat cerebral cortex in vitro. 2003 Neurochem. Res. pmid:12892042
Boushaba R et al. Kinetics of whole serum and prepurified IgG digestion by pepsin for F(ab')2 manufacture. Biotechnol. Prog. pmid:12892479
Wang Z and Zhang Q [Study on pulmonary delivery system of salmon calcitonin in rats]. 2003 Beijing Da Xue Xue Bao pmid:12914259
Massillon D et al. Regulation of glucose-6-phosphatase gene expression in cultured hepatocytes and H4IIE cells by short-chain fatty acids: role of hepatic nuclear factor-4alpha. 2003 J. Biol. Chem. pmid:12915406
Lu XY et al. Production of poly(3-hydroxybutyrate- co-3-hydroxyhexanoate) with flexible 3-hydroxyhexanoate content in Aeromonas hydrophila CGMCC 0911. 2004 Appl. Microbiol. Biotechnol. pmid:12920488
Dieterle F et al. Urinary nucleosides as potential tumor markers evaluated by learning vector quantization. 2003 Artif Intell Med pmid:12927336
Guy JE et al. The structure of an alcohol dehydrogenase from the hyperthermophilic archaeon Aeropyrum pernix. 2003 J. Mol. Biol. pmid:12927540
Vincent G et al. Differential modulation of citrate synthesis and release by fatty acids in perfused working rat hearts. 2004 Am. J. Physiol. Heart Circ. Physiol. pmid:12933348
Johnston A et al. Low pH, caprylate incubation as a second viral inactivation step in the manufacture of albumin. Parametric and validation studies. 2003 Biologicals pmid:12935811
Hiraoka T et al. Effects of oral stimulation with fats on the cephalic phase of pancreatic enzyme secretion in esophagostomized rats. 2003 Physiol. Behav. pmid:12954413
Nakajima I et al. Growth arrest by octanoate is required for porcine preadipocyte differentiation. 2003 Biochem. Biophys. Res. Commun. pmid:12963048
Richards JG et al. Palmitate movement across red and white muscle membranes of rainbow trout. 2004 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:12969874
Kaiya H et al. Peptide purification, complementary deoxyribonucleic acid (DNA) and genomic DNA cloning, and functional characterization of ghrelin in rainbow trout. 2003 Endocrinology pmid:12970156
Giron D et al. Analysis of mono-, di- and triglycerides in pharmaceutical excipients by capillary supercritical fluid chromatography. 1992 Oct-Dec J Pharm Biomed Anal pmid:1298389
REICH WJ et al. The treatment of monilial vaginitis with caprylic acid. 1953 Am. J. Obstet. Gynecol. pmid:13016687
GEYER RP et al. Effect of pyruvate on octanoate metabolism as influenced by potassium and lithium. 1953 J. Biol. Chem. pmid:13084632
BROWN GW et al. On the unequal conversion of the carboxyl and seventh carbons of octanoate to CO2 by liver slices. 1954 Arch. Biochem. Biophys. pmid:13159319
CHAPMAN DD et al. A comparison of the oxidation of octanoate-1-C14, -7-C14, and butyrate-1-C14 by neoplastic and normal mouse tissues. 1954 Cancer Res. pmid:13160966
Stace PB et al. Cyclic AMP and free fatty acids in the longer-term regulation of pyruvate dehydrogenase kinase in rat soleus muscle. 1992 Biochim. Biophys. Acta pmid:1319745
LOSSOW WJ et al. The action of insulin in sparing fatty acid oxidation: a study with palmitic acid-1-C14 and octanoate-1-C14. 1956 J. Biol. Chem. pmid:13331942