| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Hemorrhage | D006470 | 15 associated lipids |
| Hepatic Encephalopathy | D006501 | 9 associated lipids |
| Carcinoma, Hepatocellular | D006528 | 140 associated lipids |
| Hepatorenal Syndrome | D006530 | 1 associated lipids |
| Hypercholesterolemia | D006937 | 91 associated lipids |
| Hypertension, Portal | D006975 | 12 associated lipids |
| Hypothyroidism | D007037 | 32 associated lipids |
| Infant, Newborn, Diseases | D007232 | 9 associated lipids |
| Inflammation | D007249 | 119 associated lipids |
octanoic acid
octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.
Cross Reference
Introduction
To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with octanoic acid?
octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with octanoic acid
PubChem Associated disorders and diseases
What pathways are associated with octanoic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with octanoic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with octanoic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with octanoic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with octanoic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with octanoic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with octanoic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Daniels T et al. | Effects of valproic acid on cardiac metabolism. | 2004 | Can. J. Physiol. Pharmacol. | pmid:15573154 |
| Forsey RG et al. | Competition between fatty acids and carbohydrate or ketone bodies as metabolic fuels for the isolated perfused heart. | 1987 | Can. J. Physiol. Pharmacol. | pmid:3107785 |
| Zhong Z et al. | Effect of fatty acids on formation, distribution, storage, and release of benzo(a)pyrene phenols and glucuronides in the isolated perfused rat liver. | 1989 | Cancer Res. | pmid:2702643 |
| BROWN GW et al. | The oxidative metabolic pattern of mouse hepatoma C954 as studied with C14-labeled acetates, propionate, octanoate, and glucose. | 1956 | Cancer Res. | pmid:13343123 |
| CHAPMAN DD et al. | A comparison of the oxidation of octanoate-1-C14, -7-C14, and butyrate-1-C14 by neoplastic and normal mouse tissues. | 1954 | Cancer Res. | pmid:13160966 |
| VESTLING CS and WILLIAMS JN | The oxidation of octanoate by liver homogenates from leucemic mice. | 1949 | Cancer Res. | pmid:15392816 |
| Layek B and Singh J | N-hexanoyl, N-octanoyl and N-decanoyl chitosans: Binding affinity, cell uptake, and transfection. | 2012 | Carbohydr Polym | pmid:24750737 |
| Yang BY et al. | Preparation and physical properties of chitin fatty acids esters. | 2009 | Carbohydr. Res. | pmid:19091309 |
| Davidson NE et al. | Synthesis, analysis and rearrangement of novel unnatural glucosinolates. | 2001 | Carbohydr. Res. | pmid:11270808 |
| Boullanger P et al. | Syntheses of amphiphilic glycosylamides from glycosyl azides without transient reduction to glycosylamines. | 2000 | Carbohydr. Res. | pmid:10702876 |
| Markey O et al. | Effect of cinnamon on gastric emptying, arterial stiffness, postprandial lipemia, glycemia, and appetite responses to high-fat breakfast. | 2011 | Cardiovasc Diabetol | pmid:21899741 |
| Money SR and York JW | Development of oral heparin therapy for prophylaxis and treatment of deep venous thrombosis. | 2001 | Cardiovasc Surg | pmid:11336843 |
| Yang J et al. | Identification of the acyltransferase that octanoylates ghrelin, an appetite-stimulating peptide hormone. | 2008 | Cell | pmid:18267071 |
| Borba-Murad GR et al. | Comparative acute effects of leptin and insulin on gluconeogenesis and ketogenesis in perfused rat liver. | 2005 Nov-Dec | Cell Biochem. Funct. | pmid:15543644 |
| Albuquerque GG et al. | Gluconeogenesis and ketogenesis in perfused liver of rats submitted to short-term insulin-induced hypoglycaemia. | Cell Biochem. Funct. | pmid:17708579 | |
| Barrena HC et al. | Ketogenesis evaluation in perfused liver of diabetic rats submitted to short-term insulin-induced hypoglycemia. | 2009 | Cell Biochem. Funct. | pmid:19623545 |
| Takenouchi T et al. | Co-treatment with dexamethasone and octanoate induces adipogenesis in 3T3-L1 cells. | 2004 | Cell Biol. Int. | pmid:14984747 |
| Perera J et al. | Neuroprotective effects of alpha lipoic Acid on haloperidol-induced oxidative stress in the rat brain. | 2011 | Cell Biosci | pmid:21711768 |
| Jordan SD et al. | Sensing the fuels: glucose and lipid signaling in the CNS controlling energy homeostasis. | 2010 | Cell. Mol. Life Sci. | pmid:20549539 |
| Nishitani N et al. | Investigation on the Surface-Confined Self-Assembly Stabilized by Hydrogen Bonds of Urea and Amide Groups: Quantitative Analysis of Concentration Dependence of Surface Coverage. | 2015 | Chem Asian J | pmid:26033832 |
| Sun X et al. | Tuning the self-assembly of oligothiophenes on chemical vapor deposition graphene: effect of functional group, solvent, and substrate. | 2014 | Chem Asian J | pmid:24839081 |
| Che CM et al. | Ruthenium-catalyzed oxidation of alkenes, alkynes, and alcohols to organic acids with aqueous hydrogen peroxide. | 2006 | Chem Asian J | pmid:17441082 |
| Siano A et al. | Interaction of acylated and substituted antimicrobial peptide analogs with phospholipid-polydiacetylene vesicles. Correlation with their biological properties. | 2011 | Chem Biol Drug Des | pmid:21496212 |
| Shah S et al. | Enhancement of lipase activity in non-aqueous media upon immobilization on multi-walled carbon nanotubes. | 2007 | Chem Cent J | pmid:18047656 |
| Nejati K and Zabihi R | Preparation and magnetic properties of nano size nickel ferrite particles using hydrothermal method. | 2012 | Chem Cent J | pmid:22462726 |
| Zhao X et al. | Assembly of the covalent linkage between lipoic acid and its cognate enzymes. | 2003 | Chem. Biol. | pmid:14700636 |
| Sun CQ et al. | The antimicrobial properties of milkfat after partial hydrolysis by calf pregastric lipase. | 2002 | Chem. Biol. Interact. | pmid:12076524 |
| Kössler F et al. | Octanol and octanoate induced inhibition of the mechanical activity of isolated frog skeletal muscles. | 1980 | Chem. Biol. Interact. | pmid:6967777 |
| Edelman LB et al. | Metabolic context affects hemodynamic response to bupivacaine in the isolated rat heart. | 2008 | Chem. Biol. Interact. | pmid:18096147 |
| Staab CA et al. | Medium-chain fatty acids and glutathione derivatives as inhibitors of S-nitrosoglutathione reduction mediated by alcohol dehydrogenase 3. | 2009 | Chem. Biol. Interact. | pmid:19428350 |
| Al-Hunaiti A et al. | Solvent free oxidation of primary alcohols and diols using thymine iron(III) catalyst. | 2010 | Chem. Commun. (Camb.) | pmid:21042629 |
| Wu R et al. | Spatially directional multiarm poly(epsilon-caprolactone) based on resorcin[4]arene cavitand core. | 2009 | Chem. Commun. (Camb.) | pmid:19319413 |
| Xu J et al. | In-line and selective phase separation of medium-chain carboxylic acids using membrane electrolysis. | 2015 | Chem. Commun. (Camb.) | pmid:25792085 |
| Igawa T et al. | Effect of absorption promoters in intranasal administration of human fibroblast interferon as a powder dosage form in rabbits. | 1989 | Chem. Pharm. Bull. | pmid:2743486 |
| Nagatsugi F et al. | 18F-labeled octanoates as potential agents for cerebral fatty acid studies. The influence of 4-substitution and the fluorine position on biodistribution. | 1995 | Chem. Pharm. Bull. | pmid:7600614 |
| Inoue T et al. | Solid-liquid phase behavior of binary fatty acid mixtures 3. Mixtures of oleic acid with capric acid (decanoic acid) and caprylic acid (octanoic acid). | 2004 | Chem. Phys. Lipids | pmid:15555607 |
| Inoue T et al. | Effect of sodium octanoate and sodium perfluorooctanoate on gel-to-liquid-crystalline phase transition of dipalmitoylphosphatidylcholine vesicle membrane. | 1988 | Chem. Phys. Lipids | pmid:3338099 |
| Costa MC et al. | The solid-liquid phase diagrams of binary mixtures of consecutive, even saturated fatty acids. | 2009 | Chem. Phys. Lipids | pmid:19520067 |
| Naalsund T et al. | Synthesis of a triantioxidant compound: combination of beta-apo-8'-carotenoic acid, selenacapryloic acid and trolox in a triglyceride. | 2001 | Chem. Phys. Lipids | pmid:11518573 |
| Fitzsimmons ME and Anders MW | Fatty acid beta-oxidation-dependent bioactivation of halogenated thiaalkanoic acids in isolated rat hepatocytes. | 1993 Sep-Oct | Chem. Res. Toxicol. | pmid:8292744 |
| Ziesmann J et al. | Chemicals in laboratory room air stimulate olfactory neurons of female Bombyx mori. | 2000 | Chem. Senses | pmid:10667991 |
| Chen V and Halpern BP | Retronasal but not oral-cavity-only identification of "purely olfactory" odorants. | 2008 | Chem. Senses | pmid:17962230 |
| Stephenson D and Halpern BP | No oral-cavity-only discrimination of purely olfactory odorants. | 2009 | Chem. Senses | pmid:18948567 |
| Su Z et al. | Rates of fatty acid oxidations by P450 compound I are pH dependent. | 2012 | Chembiochem | pmid:22890798 |
| Mali KS et al. | Hydrogen bonding versus van der Waals interactions: competitive influence of noncovalent interactions on 2D self-assembly at the liquid-solid interface. | 2010 | Chemistry | pmid:21064044 |
| Coll C et al. | Fatty acid carboxylate- and anionic surfactant-controlled delivery systems that use mesoporous silica supports. | 2010 | Chemistry | pmid:20645326 |
| Albrecht M et al. | Preparation of tripeptide-bridged dicatechol ligands and their macrocyclic molybdenum(VI) complexes: fixation of the RGD sequence and the WKY sequence of urotensin ii in a cyclic conformation. | 2004 | Chemistry | pmid:15281149 |
| Gunschera J et al. | Surface-catalysed reactions on pollutant-removing building products for indoor use. | 2009 | Chemosphere | pmid:19181362 |
| Coenen MJ et al. | Nanostructuring of self-assembled porphyrin networks at a solid/liquid interface: local manipulation under global control. | 2014 | Chemphyschem | pmid:25146424 |
| Woo JY and Kim BK | Surfactant effects on morphology and switching of holographic PDLCs based on polyurethane acrylates. | 2007 | Chemphyschem | pmid:17146810 |
| Riniker S et al. | Temperature dependence of the dielectric permittivity of acetic acid, propionic acid and their methyl esters: a molecular dynamics simulation study. | 2012 | Chemphyschem | pmid:22383366 |
| Ishida T et al. | Base-free direct oxidation of 1-octanol to octanoic acid and its octyl ester over supported gold catalysts. | 2012 | ChemSusChem | pmid:23065901 |
| Chace KV and Odessey R | The utilization by rabbit aorta of carbohydrates, fatty acids, ketone bodies, and amino acids as substrates for energy production. | 1981 | Circ. Res. | pmid:7226445 |
| Dagher Z et al. | Acute regulation of fatty acid oxidation and amp-activated protein kinase in human umbilical vein endothelial cells. | 2001 | Circ. Res. | pmid:11420304 |
| Gonze MD et al. | Orally administered unfractionated heparin with carrier agent is therapeutic for deep venous thrombosis. | 2000 | Circulation | pmid:10840020 |
| Fieker A et al. | Enzyme replacement therapy for pancreatic insufficiency: present and future. | 2011 | Clin Exp Gastroenterol | pmid:21753892 |
| Rahman K | Studies on free radicals, antioxidants, and co-factors. | 2007 | Clin Interv Aging | pmid:18044138 |
| Müller T et al. | Impact of gastric emptying on levodopa pharmacokinetics in Parkinson disease patients. | 2006 Mar-Apr | Clin Neuropharmacol | pmid:16614536 |
| Brun AC et al. | The effect of protein composition in liquid meals on gastric emptying rate in children with cerebral palsy. | 2012 | Clin Nutr | pmid:21835514 |
| Horner KM et al. | Reproducibility of gastric emptying in overweight and obese males. | 2014 | Clin Nutr | pmid:24074547 |
| Brun AC et al. | Nissen fundoplication in children with cerebral palsy: influence on rate of gastric emptying and postprandial symptoms in relation to protein source in caloric liquid meals. | 2013 | Clin Nutr | pmid:23196118 |
| Ring J et al. | Anaphylactoid reactions to infusions of plasma protein and human serum albumin. Role of aggregated proteins and of stabilizers added during production. | 1979 | Clin. Allergy | pmid:421339 |
| Bradt BM et al. | Documentation of idiotypic cascade after Lym-1 radioimmunotherapy in a patient with non-Hodgkin's lymphoma: basis for extended survival? | 2003 | Clin. Cancer Res. | pmid:14506201 |
| Dean HG et al. | HPLC analysis of brain and plasma for octanoic and decanoic acids. | 1989 | Clin. Chem. | pmid:2776322 |
| Haidukewych D et al. | Monitoring octanoic and decanoic acids in plasma from children with intractable epilepsy treated with medium-chain triglyceride diet. | 1982 | Clin. Chem. | pmid:7074833 |
| Rabinowitz JL et al. | A method for serum octanoate in hepatic cirrhosis and hepatic encephalopathy. | 1977 | Clin. Chem. | pmid:923071 |
| Shigematsu Y et al. | (omega-1)-Hydroxymonocarboxylic acids in urine of infants fed medium-chain triglycerides. | 1981 | Clin. Chem. | pmid:7285316 |
| Onkenhout W et al. | Identification and quantification of intermediates of unsaturated fatty acid metabolism in plasma of patients with fatty acid oxidation disorders. | 1995 | Clin. Chem. | pmid:7586519 |
| Eriksson S et al. | Negative interference in cardiac troponin I immunoassays by circulating troponin autoantibodies. | 2005 | Clin. Chem. | pmid:15718489 |
| Duran M et al. | Cis-4-decenoic acid in plasma: a characteristic metabolite in medium-chain acyl-CoA dehydrogenase deficiency. | 1988 | Clin. Chem. | pmid:3349606 |
| Schadewaldt P et al. | Application of isotope-selective nondispersive infrared spectrometry (IRIS) for evaluation of [13C]octanoic acid gastric-emptying breath tests: comparison with isotope ratio-mass spectrometry (IRMS). | 1997 | Clin. Chem. | pmid:9068597 |
| Chan SC | Monitoring serum valproic acid by gas chromatography with electron-capture detection. | 1980 | Clin. Chem. | pmid:6774836 |
| Hulshoff A and Roseboom H | Determination of valproic acid (di-N-propyl acetic acid) in plasma by gas-liquid chromatography with pre-column butylation. | 1979 | Clin. Chim. Acta | pmid:373927 |
| Kimura M et al. | A sensitive and simplified method to analyze free fatty acids in children with mitochondrial beta oxidation disorders using gas chromatography/mass spectrometry and dried blood spots. | 2002 | Clin. Chim. Acta | pmid:11750281 |
| Tangerman A et al. | Quantitative determination of C2-C8 volatile fatty acids in human serum by vacuum distillation and gas chromatography. | 1983 | Clin. Chim. Acta | pmid:6627690 |
| Duran M et al. | Octanoylglucuronide excretion in patients with a defective oxidation of medium-chain fatty acids. | 1985 | Clin. Chim. Acta | pmid:4064333 |
| Fellenberg AJ and Pollard AC | A rapid and sensitive gas-liquid chromatographic procedure for the micro determination of sodium valproate (sodium di-N-propylacetate) in plasma or serum. | 1977 | Clin. Chim. Acta | pmid:338203 |
| Sanaka M et al. | The Wagner-Nelson method makes the [13C]-breath test comparable to radioscintigraphy in measuring gastric emptying of a solid/liquid mixed meal in humans. | 2007 | Clin. Exp. Pharmacol. Physiol. | pmid:17581222 |
| Symonds EL et al. | Assessment of gastric emptying in the mouse using the [13C]-octanoic acid breath test. | 2000 | Clin. Exp. Pharmacol. Physiol. | pmid:10972530 |
| Sanaka M et al. | Wagner-Nelson method for analysing the atypical double-peaked [13CO2] excretion curve in the [13C]-octanoate gastric emptying breath test in humans. | 2005 | Clin. Exp. Pharmacol. Physiol. | pmid:16026520 |
| Baraldi M et al. | An increase in cerebral benzodiazepine receptors induced by a subacute administration of ammonia, mercaptans and short-chain fatty acids in rats. | 1987 | Clin. Sci. | pmid:2826071 |
| Goldstein JL et al. | Surviving starvation: essential role of the ghrelin-growth hormone axis. | 2011 | Cold Spring Harb. Symp. Quant. Biol. | pmid:21785007 |
| Falamarzian A and Lavasanifar A | Optimization of the hydrophobic domain in poly(ethylene oxide)-poly(varepsilon-caprolactone) based nano-carriers for the solubilization and delivery of Amphotericin B. | 2010 | Colloids Surf B Biointerfaces | pmid:20674292 |
| James-Smith MA et al. | Effect of chain length on binding of fatty acids to Pluronics in microemulsions. | 2008 | Colloids Surf B Biointerfaces | pmid:18155450 |
| Bahtz J et al. | Adsorption of octanoic acid at the water/oil interface. | 2009 | Colloids Surf B Biointerfaces | pmid:19766464 |
| Adamczak M | Characteristic of fungal lipases and their application in synthesis of structered lipids. | 2003 | Commun. Agric. Appl. Biol. Sci. | pmid:24757817 |
| Sanosaka M et al. | A combination of octanoate and oleate promotes in vitro differentiation of porcine intramuscular adipocytes. | 2008 | Comp. Biochem. Physiol. B, Biochem. Mol. Biol. | pmid:17977041 |
| Guillot E et al. | Octanoate metabolism in primary culture of chicken hepatocytes: evidence for high-capacity octanoate esterification. | 1997 | Comp. Biochem. Physiol. B, Biochem. Mol. Biol. | pmid:9440218 |
| Thomas JD et al. | The carboxylic and amino acid chemoreception niche of Bulinus rohlfsi (Clessin), the snail host of Schistosoma haematobium. | 1985 | Comp. Biochem. Physiol. C, Comp. Pharmacol. Toxicol. | pmid:2865079 |
| Butler SM et al. | Fatty acid metabolism of the perfused caudate lobe from livers of fed and fasted non-pregnant and fasted late pregnant ewes. | 1988 | Comp. Biochem. Physiol., B | pmid:3197392 |
| Brady LJ et al. | Gluconeogenesis in isolated chicken (Gallus domesticus) liver cells. | 1979 | Comp. Biochem. Physiol., B | pmid:318406 |
| Tachibana S et al. | Octanoate inhibits very low-density lipoprotein secretion in primary cultures of chicken hepatocytes. | 2002 | Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. | pmid:12044771 |
| Peachey SE et al. | Gastrointestinal transit times in young and old cats. | 2000 | Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. | pmid:10908855 |
| Katoh K et al. | Saturated fatty acids suppress adrenocorticotropic hormone (ACTH) release from rat anterior pituitary cells in vitro. | 2004 | Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. | pmid:15123208 |
| Librán-Pérez M et al. | Response of hepatic lipid and glucose metabolism to a mixture or single fatty acids: Possible presence of fatty acid-sensing mechanisms. | 2013 | Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. | pmid:23010243 |
| Librán-Pérez M et al. | In vitro response of putative fatty acid-sensing systems in rainbow trout liver to increased levels of oleate or octanoate. | 2013 | Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. | pmid:23542747 |
| Redwan el-RM et al. | Ovine anti-rabies antibody production and evaluation. | 2009 | Comp. Immunol. Microbiol. Infect. Dis. | pmid:18242705 |
| Redwan el-RM et al. | Production and purification of ovine anti-tetanus antibody. | 2005 | Comp. Immunol. Microbiol. Infect. Dis. | pmid:15857656 |
| Mohanty JG and Elazhary Y | Purification of IgG from serum with caprylic acid and ammonium sulphate precipitation is not superior to ammonium sulphate precipitation alone. | 1989 | Comp. Immunol. Microbiol. Infect. Dis. | pmid:2612135 |
| Robinson MK | Intra-individual variations in acute and cumulative skin irritation responses. | 2001 | Contact Derm. | pmid:11553116 |