octanoic acid

octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.

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Introduction

To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with octanoic acid?

octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with octanoic acid

MeSH term MeSH ID Detail
Esophageal Motility Disorders D015154 1 associated lipids
Critical Illness D016638 13 associated lipids
Liver Failure D017093 5 associated lipids
Prion Diseases D017096 2 associated lipids
Skin Diseases, Bacterial D017192 8 associated lipids
Gastroparesis D018589 2 associated lipids
Endotoxemia D019446 27 associated lipids
Intracranial Hypertension D019586 4 associated lipids
REM Sleep Behavior Disorder D020187 1 associated lipids
Essential Tremor D020329 2 associated lipids
Gallstones D042882 3 associated lipids
Severe Acute Respiratory Syndrome D045169 1 associated lipids
Drug-Related Side Effects and Adverse Reactions D064420 3 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with octanoic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with octanoic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with octanoic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with octanoic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with octanoic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with octanoic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with octanoic acid

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Authors Title Published Journal PubMed Link
Derr RF and Draves K Methanethiol metabolism in the rat. 1983 Res. Commun. Chem. Pathol. Pharmacol. pmid:6407074
Becker CM and Harris RA Influence of valproic acid on hepatic carbohydrate and lipid metabolism. 1983 Arch. Biochem. Biophys. pmid:6407400
Abidova SS and Ovchinnikov IV [Effect of novodrin on fatty acid oxidation by the myocardial mitochondria of white rats]. 1983 Jul-Aug Farmakol Toksikol pmid:6617836
Otto DA Relationship of the ATP/ADP ratio to the site of octanoate activation. 1984 J. Biol. Chem. pmid:6715356
Wagenmakers AJ et al. Increase of the activity state and loss of total activity of the branched-chain 2-oxo acid dehydrogenase in rat diaphragm during incubation. 1984 Biochem. J. pmid:6517861
Schönfeld P et al. Influence of octanoate on the rate of oxidative phosphorylation and the associated extramitochondrial ATP/ADP ratios studied with isolated rat liver mitochondria oxidizing pyruvate. 1984 Biomed. Biochim. Acta pmid:6525184
Pappas SC et al. Visual evoked potentials in a rabbit model of hepatic encephalopathy. II. Comparison of hyperammonemic encephalopathy, postictal coma, and coma induced by synergistic neurotoxins. 1984 Gastroenterology pmid:6693016
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Bell FP Di(2-ethylhexyl)adipate (DEHA): effect on plasma lipids and hepatic cholesterolgenesis in the rat. 1984 Bull Environ Contam Toxicol pmid:6697017
Nauclér J et al. Evaluation of kidney viability during hypothermic perfusion or cold storage. 1984 Eur Surg Res pmid:6698069
Silavin SL et al. Reevaluation of the effects of cytochalasins on steroidogenesis: studies on hamster granulosa cells. 1984 Endocrinology pmid:6592092
Martin-Sanz P et al. Long-chain fatty acids and their acyl-CoA esters cause the translocation of phosphatidate phosphohydrolase from the cytosolic to the microsomal fraction of rat liver. 1984 FEBS Lett. pmid:6090213
Sundin U et al. Thyroid-catecholamine interactions in isolated rat brown adipocytes. 1984 Metab. Clin. Exp. pmid:6092828
Baraldi M et al. Toxins in hepatic encephalopathy: the role of the synergistic effect of ammonia, mercaptans and short chain fatty acids. 1984 Arch. Toxicol. Suppl. pmid:6097201
Claycomb WC et al. Culture of the terminally differentiated ventricular cardiac muscle cell. Characterization of exogenous substrate oxidation and the adenylate cyclase system. 1984 FEBS Lett. pmid:6201398
White RH The biosynthesis of n-[(2)H (7)] fatty acids byArthrobacter globiformis from [U-(2)H (15)] octanoic acid. 1984 Lipids pmid:21344284
Chen V et al. Regulation of substrate oxidation in isolated myocardial cells by beta-hydroxybutyrate. 1984 Horm. Metab. Res. pmid:6735347
Soboll S et al. Influence of fatty acids on energy metabolism. 2. Kinetics of changes in metabolic rates and changes in subcellular adenine nucleotide contents and pH gradients following addition of octanoate and oleate in perfused rat liver. 1984 Eur. J. Biochem. pmid:6723661
Aurousseau B et al. [Effect of the replacement of a part of the tallow in a milk supply with tricaprylin or coconut oil on the use of energy and nitrogen by the preruminant calf]. 1984 Reprod Nutr Dev pmid:6729239
Kochel PJ et al. Effects of noncarbohydrate substrates on protein synthesis in hearts from fed and fasted rats. 1984 J. Mol. Cell. Cardiol. pmid:6374161