octanoic acid

octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.

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Introduction

To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with octanoic acid?

octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with octanoic acid

MeSH term MeSH ID Detail
Essential Tremor D020329 2 associated lipids
Intracranial Hypertension D019586 4 associated lipids
Hepatorenal Syndrome D006530 1 associated lipids
Flatulence D005414 1 associated lipids
Skin Diseases, Bacterial D017192 8 associated lipids
Urinary Incontinence D014549 4 associated lipids
Chest Pain D002637 4 associated lipids
Giardiasis D005873 3 associated lipids
Severe Acute Respiratory Syndrome D045169 1 associated lipids
Chronic Disease D002908 7 associated lipids
Drug-Related Side Effects and Adverse Reactions D064420 3 associated lipids
REM Sleep Behavior Disorder D020187 1 associated lipids
Dumping Syndrome D004377 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with octanoic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with octanoic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with octanoic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with octanoic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with octanoic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with octanoic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with octanoic acid

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Authors Title Published Journal PubMed Link
Carrington MJ et al. Octanoate and palmitate as substrates for ketogenesis by hepatocytes isolated from suckling rabbits. 1981 Biochem. Soc. Trans. pmid:7215663
Borg LA Effects of octanoate and ketone and bodies on the structure and function of isolated pancreatic islets in tissue culture. 1981 Acta Endocrinol. pmid:7010865
Rosario P and Medina JM Antiketogenic effect of gluconeogenic substrates. II. Effect of pyruvate. 1981 Rev. Esp. Fisiol. pmid:7244329
Sumbilla CM et al. Comparison of the oxidation of glutamine, glucose, ketone bodies and fatty acids by human diploid fibroblasts. 1981 Biochim. Biophys. Acta pmid:7272339
Shigematsu Y et al. (omega-1)-Hydroxymonocarboxylic acids in urine of infants fed medium-chain triglycerides. 1981 Clin. Chem. pmid:7285316
Balint JA et al. Desaturation of endogenous and exogenous palmitate in lung tissue in vitro. 1981 Lipids pmid:7300595
Kragh-Hansen U Effects of aliphatic fatty acids on the binding of Phenol Red to human serum albumin. 1981 Biochem. J. pmid:7316975
Bauché F et al. 2-Mercaptoacetate administration depresses the beta-oxidation pathway through an inhibition of long-chain acyl-CoA dehydrogenase activity. 1981 Biochem. J. pmid:7317017
Ebbesen F and Brodersen R Albumin administration combined with phototherapy in treatment of hyperbilirubinaemia in low-birth-weight infants. 1981 Acta Paediatr Scand pmid:7324912
Einarsson M et al. Removal of hepatitis B virus from a concentrate of coagulation factors II, VII, IX and X by hydrophobic interaction chromatography. 1981 J. Virol. Methods pmid:7328163
Kaler LW and Neaves WB The steroidogenic capacity of the aging rat testis. 1981 J Gerontol pmid:7252069
Dimenna GP and Emery RS Palmitate and octanoate metabolism in bovine mammary tissue. 1981 J. Dairy Sci. pmid:7264015
Wells JW et al. The biosynthesis of progesterone by fowl granulosa cells in vitro from 14C-labelled substrates. 1981 J. Steroid Biochem. pmid:7265968
Trauner DA and Adams H Intracranial pressure elevations during octanoate infusion in rabbits: an experimental model of Reye's syndrome. 1981 Pediatr. Res. pmid:7267183
Felix R and Fleisch H Increase in fatty acid oxidation in calvaria cells cultured with diphosphonates. 1981 Biochem. J. pmid:6458286
Burns AH and Reddy WJ Effect of ouabain on exogenous substrate oxidation by isolated cardiac myocytes. 1981 Res. Commun. Chem. Pathol. Pharmacol. pmid:6267674
Müller MJ et al. Effect of thyroid state on ketogenic capacity of the isolated perfused liver of starved rats. 1981 Biochim. Biophys. Acta pmid:6275888
Buchowicz I et al. Anti-pseudomonas immunoglobulin. II. Preparation of purified sheep immunoglobulins. 1981 Arch. Immunol. Ther. Exp. (Warsz.) pmid:6812541
Seydoux J et al. Functional disconnection of brown adipose tissue in hypothalamic obesity in rats. 1981 Pflugers Arch. pmid:7195549
Turakulov IaKh et al. [Oxidation of palmityl carnitine in mitochondria of rat heart and liver tissue under conditions of thyroid pathology]. 1981 Mar-Apr Vopr. Med. Khim. pmid:7281559