octanoic acid

octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.

Cross Reference

Introduction

To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with octanoic acid?

octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with octanoic acid

MeSH term MeSH ID Detail
Essential Tremor D020329 2 associated lipids
Intracranial Hypertension D019586 4 associated lipids
Hepatorenal Syndrome D006530 1 associated lipids
Flatulence D005414 1 associated lipids
Skin Diseases, Bacterial D017192 8 associated lipids
Urinary Incontinence D014549 4 associated lipids
Chest Pain D002637 4 associated lipids
Giardiasis D005873 3 associated lipids
Severe Acute Respiratory Syndrome D045169 1 associated lipids
Chronic Disease D002908 7 associated lipids
Drug-Related Side Effects and Adverse Reactions D064420 3 associated lipids
REM Sleep Behavior Disorder D020187 1 associated lipids
Dumping Syndrome D004377 1 associated lipids
Per page 10 20 50 100 | Total 73

PubChem Associated disorders and diseases

What pathways are associated with octanoic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with octanoic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with octanoic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with octanoic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with octanoic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with octanoic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with octanoic acid

Download all related citations
Per page 10 20 50 100 | Total 2110
Authors Title Published Journal PubMed Link
Tenreiro S et al. AQR1 gene (ORF YNL065w) encodes a plasma membrane transporter of the major facilitator superfamily that confers resistance to short-chain monocarboxylic acids and quinidine in Saccharomyces cerevisiae. 2002 Biochem. Biophys. Res. Commun. pmid:11922628
Nakajima I et al. Growth arrest by octanoate is required for porcine preadipocyte differentiation. 2003 Biochem. Biophys. Res. Commun. pmid:12963048
Yamato M et al. Exogenous administration of octanoic acid accelerates octanoylated ghrelin production in the proventriculus of neonatal chicks. 2005 Biochem. Biophys. Res. Commun. pmid:15953586
Ohgusu H et al. Ghrelin O-acyltransferase (GOAT) has a preference for n-hexanoyl-CoA over n-octanoyl-CoA as an acyl donor. 2009 Biochem. Biophys. Res. Commun. pmid:19501572
Bjorge SM and Baillie TA Inhibition of medium-chain fatty acid beta-oxidation in vitro by valproic acid and its unsaturated metabolite, 2-n-propyl-4-pentenoic acid. 1985 Biochem. Biophys. Res. Commun. pmid:3933498
Maddaiah VT Ammonium inhibition of fatty acid oxidation in rat liver mitochondria. A possible cause of fatty liver in Reye's syndrome and urea cycle defects. 1985 Biochem. Biophys. Res. Commun. pmid:3977937
May JM et al. Cellular disulfide-reducing capacity: an integrated measure of cell redox capacity. 2006 Biochem. Biophys. Res. Commun. pmid:16650819
Hosoda H et al. Ghrelin and des-acyl ghrelin: two major forms of rat ghrelin peptide in gastrointestinal tissue. 2000 Biochem. Biophys. Res. Commun. pmid:11162448
Shanado Y et al. Lysophospholipase I identified as a ghrelin deacylation enzyme in rat stomach. 2004 Biochem. Biophys. Res. Commun. pmid:15555596
Matsumoto M et al. Structure-activity relationship of ghrelin: pharmacological study of ghrelin peptides. 2001 Biochem. Biophys. Res. Commun. pmid:11549267
Olivieri MC and Botelho LH Synergistic inhibition of hepatic ketogenesis in the presence of insulin and a cAMP antagonist. 1989 Biochem. Biophys. Res. Commun. pmid:2539126
Suzuki S et al. Characterization of actions of octanoate on porcine preadipocytes and adipocytes differentiated in vitro. 2013 Biochem. Biophys. Res. Commun. pmid:23376076
Oettl K et al. An apparent decrease in cholesterol biosynthesis in peroxisomal-defective Chinese hamster ovary cells is related to impaired mitochondrial oxidation. 2003 Biochem. Biophys. Res. Commun. pmid:12767923
Tsai CS and al-Kassim LS Multifunctional activities of pickerel liver alcohol dehydrogenase. 1993 Sep-Oct Biochem. Cell Biol. pmid:8192894
Palabost-Charles L Selection at the alpha-Gpdh locus in experimental populations of Drosophila melanogaster. 1982 Biochem. Genet. pmid:6810873
Bijlsma R Polymorphism at the G6pd and 6Pgd loci in Drosophila melanogaster. IV. Genetic factors modifying enzyme activity. 1980 Biochem. Genet. pmid:6781470
Ferré P et al. Relationship between ketogenesis and gluconeogenesis in isolated hepatocytes from newborn rats. 1981 Biochem. J. pmid:7340842
Rofe AM and Williamson DH Metabolic effects of vasopressin infusion in the starved rat. Reversal of ketonaemia. 1983 Biochem. J. pmid:6135420
Wilson MB Control of phosphoenolpyruvate synthesis in guinea-pig mitochondria. 1973 Biochem. J. pmid:4724589
Boveris A and Chance B The mitochondrial generation of hydrogen peroxide. General properties and effect of hyperbaric oxygen. 1973 Biochem. J. pmid:4749271