octanoic acid

octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.

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Introduction

To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with octanoic acid?

octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with octanoic acid

MeSH term MeSH ID Detail
Essential Tremor D020329 2 associated lipids
Intracranial Hypertension D019586 4 associated lipids
Hepatorenal Syndrome D006530 1 associated lipids
Flatulence D005414 1 associated lipids
Skin Diseases, Bacterial D017192 8 associated lipids
Urinary Incontinence D014549 4 associated lipids
Chest Pain D002637 4 associated lipids
Giardiasis D005873 3 associated lipids
Severe Acute Respiratory Syndrome D045169 1 associated lipids
Chronic Disease D002908 7 associated lipids
Drug-Related Side Effects and Adverse Reactions D064420 3 associated lipids
REM Sleep Behavior Disorder D020187 1 associated lipids
Dumping Syndrome D004377 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with octanoic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with octanoic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with octanoic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with octanoic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with octanoic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with octanoic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with octanoic acid

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Authors Title Published Journal PubMed Link
Rhead WJ et al. Dicarboxylic aciduria: deficient [1-14C]octanoate oxidation and medium-chain acyl-CoA dehydrogenase in fibroblasts. 1983 Science pmid:6857268
Parker WD et al. Effects of octanoate on rat brain and liver mitochondria. 1983 Neurology pmid:6684238
Deaciuc IV et al. Studies on the mechanism of action of the hypoglycemic agent, 2-(3-methylcinnamylhydrazono)-propionate (BM 42.304). 1983 Biochem. Pharmacol. pmid:6651864
Russo C et al. Re.: Purification of IgG monoclonal antibody by caprylic acid precipitation. 1983 J. Immunol. Methods pmid:6655243
Bauché F et al. Inhibition in vitro of acyl-CoA dehydrogenases by 2-mercaptoacetate in rat liver mitochondria. 1983 Biochem. J. pmid:6661181
Pégorier JP et al. Metabolic fate of non-esterified fatty acids in isolated hepatocytes from newborn and young pigs. Evidence for a limited capacity for oxidation and increased capacity for esterification. 1983 Biochem. J. pmid:6870859
Shapiro IM et al. Studies of nucleotides of growth-plate cartilage: evidence linking changes in cellular metabolism with cartilage calcification. 1983 Biosci. Rep. pmid:6871381
Shimizu H [Comparative studies on perfused adult and fetal guinea pig liver metabolism before and after anoxia loadings, with special reference to intracellular redox state]. 1983 Nippon Sanka Fujinka Gakkai Zasshi pmid:6875338
Rabinowitz JL et al. Lipid composition and de novo lipid biosynthesis of human palmar fat in Dupuytren's disease. 1983 Lipids pmid:6877040
Seydoux J et al. Brown adipose tissue metabolism in streptozotocin-diabetic rats. 1983 Endocrinology pmid:6223804
Bell FP Effect of the plasticizer di(2-ethylhexyl) adipate (dioctyladipate, DOA) on lipid metabolism in the rat: I. Inhibition of cholesterolgenesis and modification of phospholipid synthesis. 1983 Lipids pmid:6855481
Werner JC et al. Fatty acid and glucose utilization in isolated, working fetal pig hearts. 1983 Am. J. Physiol. pmid:6869527
Hjelmeland LM et al. A new class of nonionic detergents with a gluconamide polar group. 1983 Anal. Biochem. pmid:6869837
Nosek TM and Crosland MB Calcium-dependent proteolysis in neural tissue is activated at physiologic intracellular Ca2+ levels and inhibited by some anticonvulsants. 1983 J. Neurobiol. pmid:6298363
Geppert EF and Elstein KH Short-term regulation of fatty acid synthesis in isolated alveolar type II cells from adult rat lung. Effects of free fatty acids and hormones. 1983 Exp. Lung Res. pmid:6305647
Zieve L et al. Toxicity of a fatty acid and ammonia: interactions with hypoglycemia and Krebs cycle inhibition. 1983 J. Lab. Clin. Med. pmid:6343534
Bielefeld DR et al. Altered sensitivity of chronic diabetic rat heart to calcium. 1983 Am. J. Physiol. pmid:6362427
McDonough KH and Spitzer JJ Effects of hypoxia and reoxygenation on adult rat heart cell metabolism. 1983 Proc. Soc. Exp. Biol. Med. pmid:6412237
Nagi MN et al. Biochemical properties of short- and long-chain rat liver microsomal trans-2-enoyl coenzyme A reductase. 1983 Arch. Biochem. Biophys. pmid:6416174
Nomura T et al. Effects of octanoate and acetate upon hepatic glycolysis and lipogenesis. 1983 Biochim. Biophys. Acta pmid:6317044