octanoic acid

octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.

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Introduction

To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with octanoic acid?

octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with octanoic acid

MeSH term MeSH ID Detail
Essential Tremor D020329 2 associated lipids
Intracranial Hypertension D019586 4 associated lipids
Hepatorenal Syndrome D006530 1 associated lipids
Flatulence D005414 1 associated lipids
Skin Diseases, Bacterial D017192 8 associated lipids
Urinary Incontinence D014549 4 associated lipids
Chest Pain D002637 4 associated lipids
Giardiasis D005873 3 associated lipids
Severe Acute Respiratory Syndrome D045169 1 associated lipids
Chronic Disease D002908 7 associated lipids
Drug-Related Side Effects and Adverse Reactions D064420 3 associated lipids
REM Sleep Behavior Disorder D020187 1 associated lipids
Dumping Syndrome D004377 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with octanoic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with octanoic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with octanoic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with octanoic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with octanoic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with octanoic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with octanoic acid

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Authors Title Published Journal PubMed Link
Komura S and Kurahashi K Biosynthesis of polymyxin E by a cell-free enzyme system. IV. Acylation of enzyme-bound L-2,4-diaminobutyric acid. 1985 J. Biochem. pmid:3861608
Chan K et al. An improved gas liquid chromatographic assay for plasma valproic acid concentrations in mentally handicapped epileptic children. 1985 Methods Find Exp Clin Pharmacol pmid:3937004
Beaufrere B et al. Apparent decreased oxidation and turnover of leucine during infusion of medium-chain triglycerides. 1985 Am. J. Physiol. pmid:3895976
Duée PH et al. Development and regulation of ketogenesis in isolated hepatocytes from newborn rabbits. 1985 Reprod Nutr Dev pmid:3992001
Lee SM et al. Prevention of the metabolic effects of 2-tetradecylglycidate by octanoic acid in the genetically diabetic mouse (db/db). 1985 Biochem Med pmid:3994695
Sabbagh E et al. 3-Mercaptopropionic acid, a potent inhibitor of fatty acid oxidation in rat heart mitochondria. 1985 J. Biol. Chem. pmid:3997873
Maublant JC et al. Effects of grisorixin on the distribution of thallium-201 and on the oxidative metabolism in cultured myocardial cells. 1985 J. Nucl. Med. pmid:3998852
Trauner DA and Garrett RS Effect of octanoate injection on rat blood-brain barrier. 1985 Jan-Feb Pediatr. Neurol. pmid:3880386
Phillips JW et al. Some unexplained features of hepatic ethanol oxidation. 1985 Jan-Feb Alcohol pmid:4015838
Zieve L et al. Ammonia, octanoate and a mercaptan depress regeneration of normal rat liver after partial hepatectomy. 1985 Jan-Feb Hepatology pmid:3967863
Trauner DA and de la Torre JC Effect of octanoate on blood-brain barrier permeability using L-dopa as a marker. 1985 Jul-Aug Pediatr. Neurol. pmid:3880408
Trice JE and Trauner DA Alterations in serum glucose and hepatic glycogen concentrations during octanoate administration in rabbits. 1985 Sep-Oct Pediatr. Neurol. pmid:3880415
Kuhara T et al. Identification and quantification of octanoyl glucuronide in the urine of children who ingested medium-chain triglycerides. 1986 Biomed. Environ. Mass Spectrom. pmid:2948585
Polácek H et al. Study of cough in anaesthetized cats with experimental pulmonary oedema. 1986 Physiol Bohemoslov pmid:2950532
Webb T Identification of interference affecting the gas-liquid chromatography analysis of valproic acid in quality control material. 1986 Pathology pmid:3097616
Whyte RK et al. Excretion of dicarboxylic and omega-1 hydroxy fatty acids by low birth weight infants fed with medium-chain triglycerides. 1986 Pediatr. Res. pmid:3080726
Merrill AR et al. Effects of exogenous fatty acids on calcium uptake by brush-border membrane vesicles from rabbit small intestine. 1986 Biochim. Biophys. Acta pmid:3081028
Veerkamp JH et al. An accurate and sensitive assay of [14C]octanoate oxidation and its application on tissue homogenates and fibroblasts. 1986 Biochim. Biophys. Acta pmid:3081042
Taylor WM et al. The stimulation of tricarboxylic acid-cycle flux by alpha-adrenergic agonists in perfused rat liver. 1986 Biochem. J. pmid:3082324
Nomura T et al. Effects of vasopressin, angiotensin II and phenylephrine on hepatic ketogenesis and fatty acid synthesis. 1986 Jpn. J. Pharmacol. pmid:3773344