octanoic acid

octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.

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Introduction

To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with octanoic acid?

octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with octanoic acid

MeSH term MeSH ID Detail
Ischemic Attack, Transient D002546 42 associated lipids
Gastrointestinal Diseases D005767 20 associated lipids
Infant, Newborn, Diseases D007232 9 associated lipids
Reye Syndrome D012202 14 associated lipids
Poultry Diseases D011201 21 associated lipids
Jaundice, Neonatal D007567 7 associated lipids
Parkinson Disease D010300 53 associated lipids
Blind Loop Syndrome D001765 3 associated lipids
Coccidiosis D003048 3 associated lipids
Schistosomiasis D012552 4 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with octanoic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with octanoic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with octanoic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with octanoic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with octanoic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with octanoic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with octanoic acid

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Authors Title Published Journal PubMed Link
Tangen O et al. Platelet reactivity ex vivo and in vivo after acute and chronic treatment with sodium caprylate. 1975 Scand. J. Clin. Lab. Invest. pmid:1129590
Vessey DA Isolation and preliminary characterization of the medium-chain fatty acid:CoA ligase responsible for activation of short- and medium-chain fatty acids in colonic mucosa from swine. 2001 Dig. Dis. Sci. pmid:11281196
Briaud I et al. Lipotoxicity of the pancreatic beta-cell is associated with glucose-dependent esterification of fatty acids into neutral lipids. 2001 Diabetes pmid:11272142
Davidson NE et al. Synthesis, analysis and rearrangement of novel unnatural glucosinolates. 2001 Carbohydr. Res. pmid:11270808
Raza S et al. Enantioselectivity in Candida antarctica lipase B: a molecular dynamics study. 2001 Protein Sci. pmid:11266619
Wyse CA et al. Assessment of the rate of solid-phase gastric emptying in ponies by means of the 13C-octanoic acid breath test: a preliminary study. 2001 Equine Vet. J. pmid:11266071
Staeffen J et al. [Hyperoctanoatemia and the hepatic encephalopathy of cirrhosis. 150 dosages in 61 patients (author's transl)]. 1979 Nouv Presse Med pmid:112576
Sibille B et al. The mitochondrial consequences of uncoupling intact cells depend on the nature of the exogenous substrate. 2001 Biochem. J. pmid:11256968
Lu X et al. [Production, characterization and purification of monoclonal antibodies against antigens of Mycobacterium tuberculosis H37Rv strain]. 2000 Zhonghua Jie He He Hu Xi Za Zhi pmid:11225032
Plante OJ et al. Automated solid-phase synthesis of oligosaccharides. 2001 Science pmid:11222853
Wiberg E et al. The distribution of caprylate, caprate and laurate in lipids from developing and mature seeds of transgenic Brassica napus L. 2000 Planta pmid:11219581
Iwahashi H High-performance liquid chromatographic determination of linoleic acid peroxide-derived radicals using electrochemical detection. 2000 J Chromatogr A pmid:11204234
Kulik W et al. Improved use of the [13C]octanoic acid breath test as intra-individual parameter to study the effect of a prokinetic drug on gastric emptying in preterm infants with oral feeding intolerance. 2001 J. Chromatogr. B Biomed. Sci. Appl. pmid:11204215
Gandhi NN and Mukherjee KD Papaya (Carica papaya) lipase with some distinct acyl and alkyl specificities as compared with microbial lipases. 2000 Biochem. Soc. Trans. pmid:11171278
Taylor SI et al. Regulation of pyruvate dehydrogenase in isolated rat liver mitochondria. Effects of octanoate, oxidation-reduction state, and adenosine triphosphate to adenosine diphosphate ratio. 1975 J. Biol. Chem. pmid:1116996
Hosoda H et al. Ghrelin and des-acyl ghrelin: two major forms of rat ghrelin peptide in gastrointestinal tissue. 2000 Biochem. Biophys. Res. Commun. pmid:11162448
Hoffmann N et al. Homologous functional expression of cryptic phaG from Pseudomonas oleovorans establishes the transacylase-mediated polyhydroxyalkanoate biosynthetic pathway. 2000 Appl. Microbiol. Biotechnol. pmid:11131392
Talley NJ et al. Failure of a motilin receptor agonist (ABT-229) to relieve the symptoms of functional dyspepsia in patients with and without delayed gastric emptying: a randomized double-blind placebo-controlled trial. 2000 Aliment. Pharmacol. Ther. pmid:11121915
Miller JR et al. Escherichia coli LipA is a lipoyl synthase: in vitro biosynthesis of lipoylated pyruvate dehydrogenase complex from octanoyl-acyl carrier protein. 2000 Biochemistry pmid:11106496
Piett V et al. Enantioseparation of anionic analytes by non-aqueous capillary electrophoresis using quinine and quinidine derivatives as chiral counter-ions. 2000 J Chromatogr A pmid:11100848