| MeSH term | MeSH ID | Detail |
|---|---|---|
| Ischemic Attack, Transient | D002546 | 42 associated lipids |
| Gastrointestinal Diseases | D005767 | 20 associated lipids |
| Infant, Newborn, Diseases | D007232 | 9 associated lipids |
| Reye Syndrome | D012202 | 14 associated lipids |
| Poultry Diseases | D011201 | 21 associated lipids |
| Jaundice, Neonatal | D007567 | 7 associated lipids |
| Parkinson Disease | D010300 | 53 associated lipids |
| Blind Loop Syndrome | D001765 | 3 associated lipids |
| Coccidiosis | D003048 | 3 associated lipids |
| Schistosomiasis | D012552 | 4 associated lipids |
octanoic acid
octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.
Cross Reference
Introduction
To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with octanoic acid?
octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with octanoic acid
PubChem Associated disorders and diseases
What pathways are associated with octanoic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with octanoic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with octanoic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with octanoic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with octanoic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with octanoic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with octanoic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Wang HH et al. | Biosynthesis of polyhydroxyalkanoate homopolymers by Pseudomonas putida. | 2011 | Appl. Microbiol. Biotechnol. | pmid:21046374 |
| Zheng X et al. | A novel cold-adapted lipase from Acinetobacter sp. XMZ-26: gene cloning and characterisation. | 2011 | Appl. Microbiol. Biotechnol. | pmid:21336927 |
| Fu Y et al. | Metabolic flux analysis of Escherichia coli MG1655 under octanoic acid (C8) stress. | 2015 | Appl. Microbiol. Biotechnol. | pmid:25620365 |
| Demirev AV et al. | The role of acyl-coenzyme A carboxylase complex in lipstatin biosynthesis of Streptomyces toxytricini. | 2010 | Appl. Microbiol. Biotechnol. | pmid:20437235 |
| Ren Q et al. | Enatiomerically pure hydroxycarboxylic acids: current approaches and future perspectives. | 2010 | Appl. Microbiol. Biotechnol. | pmid:20393709 |
| Delamarre SC and Batt CA | Comparative study of promoters for the production of polyhydroxyalkanoates in recombinant strains of Wautersia eutropha. | 2006 | Appl. Microbiol. Biotechnol. | pmid:16362422 |
| Conte E et al. | Regulation of polyhydroxyalkanoate synthases (phaC1 and phaC2) gene expression in Pseudomonas corrugata. | 2006 | Appl. Microbiol. Biotechnol. | pmid:16607528 |
| Lu XY et al. | Production of poly(3-hydroxybutyrate- co-3-hydroxyhexanoate) with flexible 3-hydroxyhexanoate content in Aeromonas hydrophila CGMCC 0911. | 2004 | Appl. Microbiol. Biotechnol. | pmid:12920488 |
| Diaz De Rienzo MA et al. | Effect of biosurfactants on Pseudomonas aeruginosa and Staphylococcus aureus biofilms in a BioFlux channel. | 2016 | Appl. Microbiol. Biotechnol. | pmid:26825819 |
| Hoffmann N et al. | Homologous functional expression of cryptic phaG from Pseudomonas oleovorans establishes the transacylase-mediated polyhydroxyalkanoate biosynthetic pathway. | 2000 | Appl. Microbiol. Biotechnol. | pmid:11131392 |
| Sato S et al. | Expression and characterization of (R)-specific enoyl coenzyme A hydratases making a channeling route to polyhydroxyalkanoate biosynthesis in Pseudomonas putida. | 2011 | Appl. Microbiol. Biotechnol. | pmid:21327961 |
| Durner R et al. | Accumulation of Poly[(R)-3-hydroxyalkanoates] in Pseudomonas oleovorans during growth with octanoate in continuous culture at different dilution rates. | 2000 | Appl. Environ. Microbiol. | pmid:10919799 |
| Hajjaj H et al. | Medium-chain fatty acids affect citrinin production in the filamentous fungus Monascus ruber. | 2000 | Appl. Environ. Microbiol. | pmid:10698780 |
| Van Immerseel F et al. | Medium-chain fatty acids decrease colonization and invasion through hilA suppression shortly after infection of chickens with Salmonella enterica serovar Enteritidis. | 2004 | Appl. Environ. Microbiol. | pmid:15184160 |
| Viegas CA et al. | The H(+)-ATPase in the plasma membrane of Saccharomyces cerevisiae is activated during growth latency in octanoic acid-supplemented medium accompanying the decrease in intracellular pH and cell viability. | 1998 | Appl. Environ. Microbiol. | pmid:9464423 |
| Solis de los Santos F et al. | Therapeutic supplementation of caprylic acid in feed reduces Campylobacter jejuni colonization in broiler chicks. | 2008 | Appl. Environ. Microbiol. | pmid:18502935 |
| Lindenkamp N et al. | Genetically modified strains of Ralstonia eutropha H16 with β-ketothiolase gene deletions for production of copolyesters with defined 3-hydroxyvaleric acid contents. | 2012 | Appl. Environ. Microbiol. | pmid:22636005 |
| Elbahloul Y and Steinbüchel A | Large-scale production of poly(3-hydroxyoctanoic acid) by Pseudomonas putida GPo1 and a simplified downstream process. | 2009 | Appl. Environ. Microbiol. | pmid:19047387 |
| Ramsay BA et al. | Effect of nitrogen limitation on long-side-chain poly-beta-hydroxyalkanoate synthesis by Pseudomonas resinovorans. | 1992 | Appl. Environ. Microbiol. | pmid:1610198 |
| Hong K et al. | Effect of C:N molar ratio on monomer composition of polyhydroxyalkanoates produced by Pseudomonas mendocina 0806 and Pseudomonas pseudoalkaligenus YS1. | 2000 | Appl. Biochem. Biotechnol. | pmid:10849851 |
| Guo YJ et al. | Inhibitory effects of fatty acids on the activity of mushroom tyrosinase. | 2010 | Appl. Biochem. Biotechnol. | pmid:20544305 |
| Reis P et al. | Lipase-catalyzed reactions at interfaces of two-phase systems and microemulsions. | 2009 | Appl. Biochem. Biotechnol. | pmid:18795240 |
| Wan HD et al. | Nonthermal effect of microwave irradiation in nonaqueous enzymatic esterification. | 2012 | Appl. Biochem. Biotechnol. | pmid:22262019 |
| Zhang K et al. | Regulation of the Docosapentaenoic Acid/Docosahexaenoic Acid Ratio (DPA/DHA Ratio) in Schizochytrium limacinum B4D1. | 2017 | Appl. Biochem. Biotechnol. | pmid:27832512 |
| GEHRIG RF and KNIGHT SG | Fatty acid oxidation by spores of Penicillium roqueforti. | 1963 | Appl Microbiol | pmid:13947000 |
| Schubert MM et al. | Coffee for morning hunger pangs. An examination of coffee and caffeine on appetite, gastric emptying, and energy intake. | 2014 | Appetite | pmid:25218717 |
| Davis R et al. | Role of (R)-specific enoyl coenzyme A hydratases of Pseudomonas sp in the production of polyhydroxyalkanoates. | 2008 | Antonie Van Leeuwenhoek | pmid:17906975 |
| Mendonça Ade L et al. | Antimicrobial activities of components of the glandular secretions of leaf cutting ants of the genus Atta. | 2009 | Antonie Van Leeuwenhoek | pmid:19214771 |
| Tian W et al. | Production of polyesters consisting of medium chain length 3-hydroxyalkanoic acids by Pseudomonas mendocina 0806 from various carbon sources. | 2000 | Antonie Van Leeuwenhoek | pmid:10696875 |
| Petschow BW et al. | Susceptibility of Helicobacter pylori to bactericidal properties of medium-chain monoglycerides and free fatty acids. | 1996 | Antimicrob. Agents Chemother. | pmid:8834870 |
| Kabara JJ et al. | Fatty acids and derivatives as antimicrobial agents. | 1972 | Antimicrob. Agents Chemother. | pmid:4670656 |
| Hogan S et al. | Eradication of Staphylococcus aureus Catheter-Related Biofilm Infections Using ML:8 and Citrox. | 2016 | Antimicrob. Agents Chemother. | pmid:27458213 |
| Rosenblatt J et al. | Caprylic acid and glyceryl trinitrate combination for eradication of biofilm. | 2015 | Antimicrob. Agents Chemother. | pmid:25534725 |
| Temiralieva GA et al. | [Prospects for the use of monoclonal antibodies in Yersinia pestis]. | 1988 | Antibiot. Khimioter. | pmid:3218993 |
| Shenin IuD and Mitrofanova VG | [Structure of pentaene antibiotic lavendofuseomycin]. | 1991 | Antibiot. Khimioter. | pmid:1892437 |
| Jensen MM et al. | Intestinal absorption of octanoic, decanoic, and linoleic acids: effect of triglyceride structure. | 1994 | Ann. Nutr. Metab. | pmid:8067685 |
| Yang H et al. | Enhancing the stereoselectivity and activity of Candida species lipase in organic solvent by noncovalent enzyme modification. | 1996 | Ann. N. Y. Acad. Sci. | pmid:8958099 |
| Bennett MJ et al. | Population screening for medium-chain acyl-CoA dehydrogenase deficiency: analysis of medium-chain fatty acids and acylglycines in blood spots. | 1994 | Ann. Clin. Biochem. | pmid:8154855 |
| Allary M and Saint-Blancard J | [Use of sodium caprylate for the separation of plasma proteins]. | 1973 Jul-Aug | Ann Pharm Fr | pmid:4793461 |
| Kuge Y et al. | Preliminary evaluation of [1-11C]octanoate as a PET tracer for studying cerebral ischemia: a PET study in rat and canine models of focal cerebral ischemia. | 2000 | Ann Nucl Med | pmid:10770584 |
| Yamazaki S et al. | Uptake of radioactive octanoate in astrocytoma cells: basic studies for application of [11C]octanoate as a PET tracer. | 1996 | Ann Nucl Med | pmid:9006724 |
| Kuge Y et al. | Brain uptake and metabolism of [1-11C]octanoate in rats: pharmacokinetic basis for its application as a radiopharmaceutical for studying brain fatty acid metabolism. | 1995 | Ann Nucl Med | pmid:8534586 |
| Kim H et al. | Topical hypopigmenting agents for pigmentary disorders and their mechanisms of action. | 2012 | Ann Dermatol | pmid:22363147 |
| Aurousseau B and de Groot L | [Effect of caprylic acid on metabolism of other fatty acids in the growing rat]. | 1972 | Ann Biol Anim Biochim Biophys | pmid:4667618 |
| Stafford CT et al. | Anaphylaxis to human serum albumin. | 1988 | Ann Allergy | pmid:3274040 |
| Sun K et al. | Rhodium-catalyzed synthesis of 2,3-disubstituted indoles from β,β-disubstituted stryryl azides. | 2011 | Angew. Chem. Int. Ed. Engl. | pmid:21308937 |
| Ward DS et al. | Pharmacodynamics and pharmacokinetics of propofol in a medium-chain triglyceride emulsion. | 2002 | Anesthesiology | pmid:12459665 |
| Chassard D et al. | Effects of subhypnotic doses of propofol on gastric emptying in volunteers. | 2002 | Anesthesiology | pmid:12131109 |
| Sueyasu M et al. | Protein binding and the metabolism of thiamylal enantiomers in vitro. | 2000 | Anesth. Analg. | pmid:10960410 |
| Bouvet L et al. | Erythromycin promotes gastric emptying during acute pain in volunteers. | 2006 | Anesth. Analg. | pmid:16717329 |
| Choi YH et al. | Lipoic acid suppresses compound 48/80-induced anaphylaxis-like reaction. | 2010 | Anat Cell Biol | pmid:21267406 |
| Bailly-Chouriberry L et al. | Detection of secondary biomarker of met-eGH as a strategy to screen for somatotropin misuse in horseracing. | 2008 | Analyst | pmid:18227952 |
| Meng Y et al. | Role of counteranions in polymeric ionic liquid-based solid-phase microextraction coatings for the selective extraction of polar compounds. | 2011 | Anal. Chim. Acta | pmid:21277416 |
| Rodrigues F et al. | Development of a dynamic headspace solid-phase microextraction procedure coupled to GC-qMSD for evaluation the chemical profile in alcoholic beverages. | 2008 | Anal. Chim. Acta | pmid:18243877 |
| Kragh-Hansen U et al. | Rate-of-dialysis technique: theoretical and practical aspects. | 2005 | Anal. Biochem. | pmid:15802140 |
| Bryant P et al. | The activity of a thermostable lipoyl synthase from Sulfolobus solfataricus with a synthetic octanoyl substrate. | 2006 | Anal. Biochem. | pmid:16500612 |
| Jones JG et al. | Determination of acetyl-CoA enrichment in rat heart and skeletal muscle by 1H nuclear magnetic resonance analysis of glutamate in tissue extracts. | 1997 | Anal. Biochem. | pmid:9212871 |
| Kunz D et al. | Flow cytometric detection of mitochondrial dysfunction in subpopulations of human mononuclear cells. | 1997 | Anal. Biochem. | pmid:9073359 |
| Hjelmeland LM et al. | A new class of nonionic detergents with a gluconamide polar group. | 1983 | Anal. Biochem. | pmid:6869837 |
| Zhu L et al. | Simultaneous sampling of volatile and non-volatile analytes in beer for fast fingerprinting by extractive electrospray ionization mass spectrometry. | 2010 | Anal Bioanal Chem | pmid:20644917 |
| Dietrich B et al. | Synthesis, characterization, and high-performance liquid chromatographic evaluation of C14 stationary phases containing branched and unbranched alkyl groups. | 2008 | Anal Bioanal Chem | pmid:18506426 |
| Takahashi H et al. | Metabolomics approach for determining growth-specific metabolites based on Fourier transform ion cyclotron resonance mass spectrometry. | 2008 | Anal Bioanal Chem | pmid:18560811 |
| Eggink M et al. | Targeted LC-MS derivatization for aldehydes and carboxylic acids with a new derivatization agent 4-APEBA. | 2010 | Anal Bioanal Chem | pmid:20238107 |
| Yamamoto K et al. | An LC method for monitoring medium-chain fatty acid permeation through CaCo-2 cell monolayers. | 2009 | Anal Bioanal Chem | pmid:19641905 |
| Urquiza M et al. | α-Helix peptides designed from EBV-gH protein display higher antigenicity and induction of monocyte apoptosis than the native peptide. | 2010 | Amino Acids | pmid:20473772 |
| McLellan J et al. | Comparison of the carbon 13-labeled octanoic acid breath test and ultrasonography for assessment of gastric emptying of a semisolid meal in dogs. | 2004 | Am. J. Vet. Res. | pmid:15566095 |
| Wyse CA et al. | Use of the 13C-octanoic acid breath test for assessment of solid-phase gastric emptying in dogs. | 2001 | Am. J. Vet. Res. | pmid:11763185 |
| Valipe SR et al. | In vitro antimicrobial properties of caprylic acid, monocaprylin, and sodium caprylate against Dermatophilus congolensis. | 2011 | Am. J. Vet. Res. | pmid:21355735 |
| Battiprolu PK et al. | Sex differences in energy metabolism and performance of teleost cardiac tissue. | 2007 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:17038442 |
| Richards JG et al. | Palmitate movement across red and white muscle membranes of rainbow trout. | 2004 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:12969874 |
| El Hafidi M et al. | Glycine intake decreases plasma free fatty acids, adipose cell size, and blood pressure in sucrose-fed rats. | 2004 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:15331379 |
| Librán-Pérez M et al. | Evidence of a metabolic fatty acid-sensing system in the hypothalamus and Brockmann bodies of rainbow trout: implications in food intake regulation. | 2012 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:22496361 |
| Sallam HS et al. | Mechanisms of burn-induced impairment in gastric slow waves and emptying in rats. | 2010 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:20427716 |
| Darling RA et al. | Mercaptoacetate and fatty acids exert direct and antagonistic effects on nodose neurons via GPR40 fatty acid receptors. | 2014 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:24760994 |
| Degen L et al. | Effect of CCK-1 receptor blockade on ghrelin and PYY secretion in men. | 2007 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:17138722 |
| Barron JT and Gu L | Energetic effects of adenosine on vascular smooth muscle. | 2000 | Am. J. Physiol. Heart Circ. Physiol. | pmid:10644580 |
| Panchal AR et al. | Partitioning of pyruvate between oxidation and anaplerosis in swine hearts. | 2000 | Am. J. Physiol. Heart Circ. Physiol. | pmid:11045976 |
| Longnus SL et al. | Regulation of myocardial fatty acid oxidation by substrate supply. | 2001 | Am. J. Physiol. Heart Circ. Physiol. | pmid:11557544 |
| Allard MF et al. | AMPK and metabolic adaptation by the heart to pressure overload. | 2007 | Am. J. Physiol. Heart Circ. Physiol. | pmid:16920812 |
| Labarthe F et al. | Fatty acid oxidation and its impact on response of spontaneously hypertensive rat hearts to an adrenergic stress: benefits of a medium-chain fatty acid. | 2005 | Am. J. Physiol. Heart Circ. Physiol. | pmid:15550523 |
| Vincent G et al. | Differential modulation of citrate synthesis and release by fatty acids in perfused working rat hearts. | 2004 | Am. J. Physiol. Heart Circ. Physiol. | pmid:12933348 |
| Kajimoto M et al. | Differential effects of octanoate and heptanoate on myocardial metabolism during extracorporeal membrane oxygenation in an infant swine model. | 2015 | Am. J. Physiol. Heart Circ. Physiol. | pmid:26232235 |
| Kajimoto M et al. | Effects of continuous triiodothyronine infusion on the tricarboxylic acid cycle in the normal immature swine heart under extracorporeal membrane oxygenation in vivo. | 2014 | Am. J. Physiol. Heart Circ. Physiol. | pmid:24531815 |
| Jørgensen J and Mortensen PB | Substrate utilization by intestinal mucosal tissue strips from patients with inflammatory bowel disease. | 2001 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:11447021 |
| Mizutani M et al. | Localization of acyl ghrelin- and des-acyl ghrelin-immunoreactive cells in the rat stomach and their responses to intragastric pH. | 2009 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:20501445 |
| Vincent G et al. | Citrate release by perfused rat hearts: a window on mitochondrial cataplerosis. | 2000 | Am. J. Physiol. Endocrinol. Metab. | pmid:10780941 |
| Kim JY et al. | Lipid oxidation is reduced in obese human skeletal muscle. | 2000 | Am. J. Physiol. Endocrinol. Metab. | pmid:11052958 |
| Benthem L et al. | Excess portal venous long-chain fatty acids induce syndrome X via HPA axis and sympathetic activation. | 2000 | Am. J. Physiol. Endocrinol. Metab. | pmid:11093916 |
| Bezaire V et al. | Identification of fatty acid translocase on human skeletal muscle mitochondrial membranes: essential role in fatty acid oxidation. | 2006 | Am. J. Physiol. Endocrinol. Metab. | pmid:16219667 |
| Cha BS et al. | Impaired fatty acid metabolism in type 2 diabetic skeletal muscle cells is reversed by PPARgamma agonists. | 2005 | Am. J. Physiol. Endocrinol. Metab. | pmid:15727952 |
| Sakata I et al. | Colocalization of ghrelin O-acyltransferase and ghrelin in gastric mucosal cells. | 2009 | Am. J. Physiol. Endocrinol. Metab. | pmid:19401456 |
| Tham E et al. | Acylated ghrelin concentrations are markedly decreased during pregnancy in mothers with and without gestational diabetes: relationship with cholinesterase. | 2009 | Am. J. Physiol. Endocrinol. Metab. | pmid:19240252 |
| Hommelberg PP et al. | Fatty acid-induced NF-kappaB activation and insulin resistance in skeletal muscle are chain length dependent. | 2009 | Am. J. Physiol. Endocrinol. Metab. | pmid:18957619 |
| Bando M et al. | Transgenic overexpression of intraislet ghrelin does not affect insulin secretion or glucose metabolism in vivo. | 2012 | Am. J. Physiol. Endocrinol. Metab. | pmid:22114024 |
| Turcotte LP et al. | High carbohydrate availability increases LCFA uptake and decreases LCFA oxidation in perfused muscle. | 2002 | Am. J. Physiol. Endocrinol. Metab. | pmid:11739099 |
| McDaniel HG | Acute suppression of hepatic gluconeogenesis by glucose in the intact animal. | 1975 | Am. J. Physiol. | pmid:1211489 |
| REES ED and KLINE DL | Metabolism of octanoate by fatty liver slices. | 1957 | Am. J. Physiol. | pmid:13470069 |
| Barron JT et al. | Substrate-dependent alteration in O2 consumption and energy metabolism in vascular smooth muscle. | 1996 | Am. J. Physiol. | pmid:8764234 |
| Hütter JF et al. | Effect of fatty acid oxidation on efficiency of energy production in rat heart. | 1985 | Am. J. Physiol. | pmid:4051011 |
| Witters LA and Trasko CS | Regulation of hepatic free fatty acid metabolism by glucagon and insulin. | 1979 | Am. J. Physiol. | pmid:157075 |