octanoic acid

octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.

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Introduction

To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with octanoic acid?

octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with octanoic acid

MeSH term MeSH ID Detail
Reye Syndrome D012202 14 associated lipids
Hemorrhage D006470 15 associated lipids
Gastrointestinal Diseases D005767 20 associated lipids
Poultry Diseases D011201 21 associated lipids
Lipid Metabolism, Inborn Errors D008052 26 associated lipids
Endotoxemia D019446 27 associated lipids
Obesity D009765 29 associated lipids
Kidney Diseases D007674 29 associated lipids
Diarrhea D003967 32 associated lipids
Hypothyroidism D007037 32 associated lipids
Per page 10 20 50 100 | Total 73

PubChem Associated disorders and diseases

What pathways are associated with octanoic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with octanoic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with octanoic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with octanoic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with octanoic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with octanoic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with octanoic acid

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Authors Title Published Journal PubMed Link
Zaleski J and Bryla J Effects of oleate, palmitate, and octanoate on gluconeogenesis in isolated rabbit liver cells. 1977 Arch. Biochem. Biophys. pmid:921276
Jones JG et al. Determination of acetyl-CoA enrichment in rat heart and skeletal muscle by 1H nuclear magnetic resonance analysis of glutamate in tissue extracts. 1997 Anal. Biochem. pmid:9212871
Leclercq P et al. Inhibition of glycerol metabolism in hepatocytes isolated from endotoxic rats. 1997 Biochem. J. pmid:9230136
Rabinowitz JL et al. A method for serum octanoate in hepatic cirrhosis and hepatic encephalopathy. 1977 Clin. Chem. pmid:923071
Coyle EF et al. Fatty acid oxidation is directly regulated by carbohydrate metabolism during exercise. 1997 Am. J. Physiol. pmid:9277379
Fowler JS et al. Carbon-11 labeled aliphatic amines in lung uptake and metabolism studies: potential for dynamic measurements in vivo. 1976 J. Pharmacol. Exp. Ther. pmid:933003
Sheikh MI Renal handling of phenol red. II. The mechanism of substituted phenolsulphophthalein (PSP) dye transport in rabbit kidney tubules in vitro. 1976 J. Physiol. (Lond.) pmid:933027
Bito LZ et al. Inhibition of in vitro concentrative prostaglandin accumulation by prostaglandins, prostaglandin analogues and by some inhibitors of organic anion transport. 1976 J. Physiol. (Lond.) pmid:933072
Gann VK and Hardin CD Acetate or octanoate increases glycogenolysis in smooth muscle as determined by 13C-NMR. 1997 Physiol Chem Phys Med NMR pmid:9353955
Chen TM et al. Effects of insulin on glucose uptake by rat hearts during and after coronary flow reduction. 1997 Am. J. Physiol. pmid:9374750
Andreev LV and Temnov AV [Determination of the specificity of microbial esterases in vivo]. 1976 Jan-Feb Mikrobiologiia pmid:940489
Guillot E et al. Octanoate metabolism in primary culture of chicken hepatocytes: evidence for high-capacity octanoate esterification. 1997 Comp. Biochem. Physiol. B, Biochem. Mol. Biol. pmid:9440218
Choi MG et al. Reproducibility and simplification of 13C-octanoic acid breath test for gastric emptying of solids. 1998 Am. J. Gastroenterol. pmid:9448183
Barron JT et al. Oxidation of acetate and octanoate and its relation to glucose metabolism in contracting porcine carotid artery. 1997 Biochim. Biophys. Acta pmid:9452767
Hillgartner FB and Charron T Arachidonate and medium-chain fatty acids inhibit transcription of the acetyl-CoA carboxylase gene in hepatocytes in culture. 1997 J. Lipid Res. pmid:9458278
Viegas CA et al. The H(+)-ATPase in the plasma membrane of Saccharomyces cerevisiae is activated during growth latency in octanoic acid-supplemented medium accompanying the decrease in intracellular pH and cell viability. 1998 Appl. Environ. Microbiol. pmid:9464423
Visarius TM et al. Thiodiglycolic acid is excreted by humans receiving ifosfamide and inhibits mitochondrial function in rats. 1998 Drug Metab. Dispos. pmid:9492379
Groves CE et al. Peritubular transport of ochratoxin A in rabbit renal proximal tubules. 1998 J. Pharmacol. Exp. Ther. pmid:9495853
Sidossis LS et al. Regulation of fatty acid oxidation in untrained vs. trained men during exercise. 1998 Am. J. Physiol. pmid:9530135
Abdel-aleem S et al. Regulation of carbohydrate and fatty acid utilization by L-carnitine during cardiac development and hypoxia. 1998 Mol. Cell. Biochem. pmid:9546635