octanoic acid

octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.

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Introduction

To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with octanoic acid?

octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with octanoic acid

MeSH term MeSH ID Detail
Reye Syndrome D012202 14 associated lipids
Hemorrhage D006470 15 associated lipids
Gastrointestinal Diseases D005767 20 associated lipids
Poultry Diseases D011201 21 associated lipids
Lipid Metabolism, Inborn Errors D008052 26 associated lipids
Endotoxemia D019446 27 associated lipids
Obesity D009765 29 associated lipids
Kidney Diseases D007674 29 associated lipids
Diarrhea D003967 32 associated lipids
Hypothyroidism D007037 32 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with octanoic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with octanoic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with octanoic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with octanoic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with octanoic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with octanoic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with octanoic acid

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Authors Title Published Journal PubMed Link
Fontaine P et al. Medium chain length polyhydroxyalkanoates biosynthesis in Pseudomonas putida mt-2 is enhanced by co-metabolism of glycerol/octanoate or fatty acids mixtures. 2017 Int. J. Biol. Macromol. pmid:28174083
Das K and Ghosh M Structured DAG oil ameliorates renal injury in streptozotocin-induced diabetic rats through inhibition of NF-κB and activation of Nrf2 pathway. 2017 Food Chem. Toxicol. pmid:28025123
Vanheel H et al. Pathophysiological Abnormalities in Functional Dyspepsia Subgroups According to the Rome III Criteria. 2017 Am. J. Gastroenterol. pmid:27958284
Kandula M et al. Discovery and preclinical development of a novel prodrug conjugate of mesalamine with eicosapentaenoic acid and caprylic acid for the treatment of inflammatory bowel diseases. 2016 Int. Immunopharmacol. pmid:27716592
Kateja N et al. Continuous precipitation of process related impurities from clarified cell culture supernatant using a novel coiled flow inversion reactor (CFIR). 2016 Biotechnol J pmid:27447837
Lemarié F et al. Effect of preduodenal lipase inhibition in suckling rats on dietary octanoic acid (C8:0) gastric absorption and plasma octanoylated ghrelin concentration. 2016 Biochim. Biophys. Acta pmid:27317984
Sawatani Y et al. Sequence-specific DNA binding by long hairpin pyrrole-imidazole polyamides containing an 8-amino-3,6-dioxaoctanoic acid unit. 2016 Bioorg. Med. Chem. pmid:27301681
Kubota K et al. The molecular assembly of the ionic liquid/aliphatic carboxylic acid/aliphatic amine as effective and safety transdermal permeation enhancers. 2016 Eur J Pharm Sci pmid:26965004
Nakajima K et al. Triterpenes suppress octanoylated ghrelin production in ghrelin-expressing human gastric carcinoma cells. 2016 Biomed. Res. pmid:28003581
Hogan S et al. Eradication of Staphylococcus aureus Catheter-Related Biofilm Infections Using ML:8 and Citrox. 2016 Antimicrob. Agents Chemother. pmid:27458213
Lockman KA et al. Proteomic profiling of cellular steatosis with concomitant oxidative stress in vitro. 2016 Lipids Health Dis pmid:27368608
Voller B et al. Dose-escalation study of octanoic acid in patients with essential tremor. 2016 J. Clin. Invest. pmid:26927672
Diaz De Rienzo MA et al. Effect of biosurfactants on Pseudomonas aeruginosa and Staphylococcus aureus biofilms in a BioFlux channel. 2016 Appl. Microbiol. Biotechnol. pmid:26825819
Obeso JI et al. The loss of function of PhaC1 is a survival mechanism that counteracts the stress caused by the overproduction of poly-3-hydroxyalkanoates in Pseudomonas putidaΔfadBA. 2015 Environ. Microbiol. pmid:25627209
Fu Y et al. Metabolic flux analysis of Escherichia coli MG1655 under octanoic acid (C8) stress. 2015 Appl. Microbiol. Biotechnol. pmid:25620365
Kajimoto M et al. Differential effects of octanoate and heptanoate on myocardial metabolism during extracorporeal membrane oxygenation in an infant swine model. 2015 Am. J. Physiol. Heart Circ. Physiol. pmid:26232235
Lemarié F et al. Dietary Caprylic Acid (C8:0) Does Not Increase Plasma Acylated Ghrelin but Decreases Plasma Unacylated Ghrelin in the Rat. 2015 PLoS ONE pmid:26196391
Genser B et al. Within- and between-group regression for improving the robustness of causal claims in cross-sectional analysis. 2015 Environ Health pmid:26159541
Xu J et al. In-line and selective phase separation of medium-chain carboxylic acids using membrane electrolysis. 2015 Chem. Commun. (Camb.) pmid:25792085
Alonso C et al. Skin delivery of antioxidant surfactants based on gallic acid and hydroxytyrosol. 2015 J. Pharm. Pharmacol. pmid:25645286