octanoic acid

octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.

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Introduction

To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with octanoic acid?

octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with octanoic acid

MeSH term MeSH ID Detail
Infant, Newborn, Diseases D007232 9 associated lipids
Hepatic Encephalopathy D006501 9 associated lipids
Skin Diseases, Bacterial D017192 8 associated lipids
Jaundice, Neonatal D007567 7 associated lipids
Stomach Diseases D013272 7 associated lipids
Chronic Disease D002908 7 associated lipids
Cholestasis, Extrahepatic D001651 7 associated lipids
Diabetic Neuropathies D003929 5 associated lipids
Dyspepsia D004415 5 associated lipids
Asthenia D001247 5 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with octanoic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with octanoic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with octanoic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with octanoic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with octanoic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with octanoic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with octanoic acid

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Authors Title Published Journal PubMed Link
Soboll S et al. Effect of long-chain fatty acyl-CoA on mitochondrial and cytosolic ATP/ADP ratios in the intact liver cell. 1984 Biochem. J. pmid:6743276
Abumrad NA et al. Permeation of long-chain fatty acid into adipocytes. Kinetics, specificity, and evidence for involvement of a membrane protein. 1984 J. Biol. Chem. pmid:6746632
Elliott JR et al. The asymmetrical effects of some ionized n-octyl derivatives on the sodium current of the giant axon of Loligo forbesi. 1984 J. Physiol. (Lond.) pmid:6747855
White RH Stable isotope studies on the biosynthesis of lipoic acid in Escherichia coli. 1980 Biochemistry pmid:6766313
Chacín J et al. Role of fatty acid oxidation in mechanism of action of gastric secretagogues. 1980 Am. J. Physiol. pmid:6768310
Chan SC Monitoring serum valproic acid by gas chromatography with electron-capture detection. 1980 Clin. Chem. pmid:6774836
Bijlsma R Polymorphism at the G6pd and 6Pgd loci in Drosophila melanogaster. IV. Genetic factors modifying enzyme activity. 1980 Biochem. Genet. pmid:6781470
Derr RF and Zieve L Effect of fatty acids on the disposition of ammonia. 1976 J. Pharmacol. Exp. Ther. pmid:6789
Abbott FS et al. Valproic acid analysis in saliva and serum using selected ion monitoring (electron ionization) of the tert.-butyldimethylsilyl derivatives. 1982 J. Chromatogr. pmid:6801067
Palabost-Charles L Selection at the alpha-Gpdh locus in experimental populations of Drosophila melanogaster. 1982 Biochem. Genet. pmid:6810873
Buchowicz I et al. Anti-pseudomonas immunoglobulin. II. Preparation of purified sheep immunoglobulins. 1981 Arch. Immunol. Ther. Exp. (Warsz.) pmid:6812541
Ledden DJ et al. Characterization of fragments of human albumin purified by Cibacron blue F3GA affinity chromatography. 1982 Biochem. J. pmid:6814424
Windus-Podehl G et al. Encephalopathic effect of phenol in rats. 1983 J. Lab. Clin. Med. pmid:6833829
Stange EF and Dietschy JM Absolute rates of cholesterol synthesis in rat intestine in vitro and in vivo: a comparison of different substrates in slices and isolated cells. 1983 J. Lipid Res. pmid:6833883
Zabłocki K et al. The inhibitory effect of octanoate, palmitate and oleate on glucose formation in rabbit kidney tubules. 1983 Biochim. Biophys. Acta pmid:6838901
Almås I et al. The action of vasopressin and calcium on palmitate metabolism in hepatocytes and isolated mitochondria from rat liver. 1983 Arch. Biochem. Biophys. pmid:6847192
Werner JC et al. Fatty acid and glucose utilization in isolated, working newborn pig hearts. 1983 Am. J. Physiol. pmid:6849379
Latipää PM et al. Regulation of fatty acid oxidation in heart muscle. Effects of pyruvate and dichloroacetate. 1983 Biochim. Biophys. Acta pmid:6849964
Mayorek N and Bar-Tana J Medium chain fatty acids as specific substrates for diglyceride acyltransferase in cultured hepatocytes. 1983 J. Biol. Chem. pmid:6853505
Bell FP Effect of the plasticizer di(2-ethylhexyl) adipate (dioctyladipate, DOA) on lipid metabolism in the rat: I. Inhibition of cholesterolgenesis and modification of phospholipid synthesis. 1983 Lipids pmid:6855481