octanoic acid

octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.

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Introduction

To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with octanoic acid?

octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with octanoic acid

MeSH term MeSH ID Detail
Insulin Resistance D007333 99 associated lipids
Jaundice, Neonatal D007567 7 associated lipids
Kidney Diseases D007674 29 associated lipids
Lipid Metabolism, Inborn Errors D008052 26 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Liver Cirrhosis, Experimental D008106 36 associated lipids
Malocclusion D008310 3 associated lipids
Memory Disorders D008569 33 associated lipids
Metabolism, Inborn Errors D008661 46 associated lipids
Obesity D009765 29 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with octanoic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with octanoic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with octanoic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with octanoic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with octanoic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with octanoic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with octanoic acid

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Authors Title Published Journal PubMed Link
Agius L and Alberti KG Regulation of flux through pyruvate dehydrogenase and pyruvate carboxylase in rat hepatocytes. Effects of fatty acids and glucagon. 1985 Eur. J. Biochem. pmid:3932072
Bjorge SM and Baillie TA Inhibition of medium-chain fatty acid beta-oxidation in vitro by valproic acid and its unsaturated metabolite, 2-n-propyl-4-pentenoic acid. 1985 Biochem. Biophys. Res. Commun. pmid:3933498
Veerkamp JH et al. Interaction of short-chain and branched-chain fatty acids and their carnitine and CoA esters and of various metabolites and agents with branched-chain 2-oxo acid oxidation in rat muscle and liver mitochondria. 1985 Int. J. Biochem. pmid:3934010
Chan K et al. An improved gas liquid chromatographic assay for plasma valproic acid concentrations in mentally handicapped epileptic children. 1985 Methods Find Exp Clin Pharmacol pmid:3937004
Stanisz J et al. Serum factors that stimulate fatty acid oxidation: physiological specificity. 1986 J. Cell. Physiol. pmid:3944194
Zieve L et al. Ammonia, octanoate and a mercaptan depress regeneration of normal rat liver after partial hepatectomy. 1985 Jan-Feb Hepatology pmid:3967863
Noy N and Zakim D Substrate specificity of fatty-acyl-CoA ligase in liver microsomes. 1985 Biochim. Biophys. Acta pmid:3970953
Ferris CF et al. Alcohol and fatty acid stimulation of neurotensin release from rat small intestine. 1985 Endocrinology pmid:3971900
Germán JC et al. [Solvent effects on cholesterol calculi: an in vitro study using octanoic acid, glycerol monooctanate, sodium cholate, heparin and ursodeoxycholic acid]. 1985 Rev Esp Enferm Apar Dig pmid:3975461
Maddaiah VT Ammonium inhibition of fatty acid oxidation in rat liver mitochondria. A possible cause of fatty liver in Reye's syndrome and urea cycle defects. 1985 Biochem. Biophys. Res. Commun. pmid:3977937
Haas R et al. Salicylate-induced loose coupling: protonmotive force measurements. 1985 Biochem. Pharmacol. pmid:3977963
Taylor WM et al. Effect of depolarizing concentrations of potassium on calcium uptake and metabolism in rat liver. 1985 FEBS Lett. pmid:3979569
Duée PH et al. Development and regulation of ketogenesis in isolated hepatocytes from newborn rabbits. 1985 Reprod Nutr Dev pmid:3992001
Lee SM et al. Prevention of the metabolic effects of 2-tetradecylglycidate by octanoic acid in the genetically diabetic mouse (db/db). 1985 Biochem Med pmid:3994695
Sabbagh E et al. 3-Mercaptopropionic acid, a potent inhibitor of fatty acid oxidation in rat heart mitochondria. 1985 J. Biol. Chem. pmid:3997873
Maublant JC et al. Effects of grisorixin on the distribution of thallium-201 and on the oxidative metabolism in cultured myocardial cells. 1985 J. Nucl. Med. pmid:3998852
Bougnères PF et al. Medium-chain acyl-CoA dehydrogenase deficiency in two siblings with a Reye-like syndrome. 1985 J. Pediatr. pmid:3998948
Roe CR et al. Diagnostic and therapeutic implications of medium-chain acylcarnitines in the medium-chain acyl-coA dehydrogenase deficiency. 1985 Pediatr. Res. pmid:4000772
McCandless DW Octanoic acid-induced coma and reticular formation energy metabolism. 1985 Brain Res. pmid:4005536
Rowley H and Collins RC [1-14C]Octanoate: a fast functional marker of brain activity. 1985 Brain Res. pmid:4005560
Phillips JW et al. Some unexplained features of hepatic ethanol oxidation. 1985 Jan-Feb Alcohol pmid:4015838
Brandes R et al. The specificity of triacylglycerol synthesis for medium-chain fatty acids in rat and human adipose preparations. 1985 Biochim. Biophys. Acta pmid:4027259
Drewes LR and Leino RL Neuron-specific mitochondrial degeneration induced by hyperammonemia and octanoic acidemia. 1985 Brain Res. pmid:4027650
Duran M et al. Octanoic acidemia and octanoylcarnitine excretion with dicarboxylic aciduria due to defective oxidation of medium-chain fatty acids. 1985 J. Pediatr. pmid:4032135
Wolf HP and Engel DW Decrease of fatty acid oxidation, ketogenesis and gluconeogenesis in isolated perfused rat liver by phenylalkyl oxirane carboxylate (B 807-27) due to inhibition of CPT I (EC 2.3.1.21). 1985 Eur. J. Biochem. pmid:4038486
Hütter JF et al. Effect of fatty acid oxidation on efficiency of energy production in rat heart. 1985 Am. J. Physiol. pmid:4051011
Lutz WH et al. Inhibition of citrulline synthesis by octanoate and its modulation by adenine nucleotides. 1985 Biochem Med pmid:4052056
Strieleman PJ et al. Fatty acid activation of the reconstituted brown adipose tissue mitochondria uncoupling protein. 1985 J. Biol. Chem. pmid:4055740
Nelis HJ et al. Chromatographic determination of N-acetyl-DL-tryptophan and octanoic acid in human albumin solutions. 1985 J. Chromatogr. pmid:4055947
Zieve L et al. Effect of hepatic failure toxins on liver thymidine kinase activity and ornithine decarboxylase activity after massive necrosis with acetaminophen in the rat. 1985 J. Lab. Clin. Med. pmid:4056569
Duran M et al. Octanoylglucuronide excretion in patients with a defective oxidation of medium-chain fatty acids. 1985 Clin. Chim. Acta pmid:4064333
Plomp PJ et al. Mechanism of the stimulation of respiration by fatty acids in rat liver. 1985 FEBS Lett. pmid:4065340
MacDonald ML et al. Aversion of the cat to dietary medium-chain triglycerides and caprylic acid. 1985 Physiol. Behav. pmid:4070410
Taguchi S [Acidosis tolerance of fetal metabolism--comparative studies on isolated perfused adult, fetal and neonatal livers]. 1985 Nippon Sanka Fujinka Gakkai Zasshi pmid:4086906
Dube VE et al. Caprylate-dependent auto-anti-e. 1977 Vox Sang. pmid:412322
Harwood JL et al. Fat metabolism in higher plants. Beta-hydroxylation of fatty acids by a soluble preparation from maturing avocado mesocarp. 1972 Biochem. J. pmid:4144293
Ring J et al. Anaphylactoid reactions to infusions of plasma protein and human serum albumin. Role of aggregated proteins and of stabilizers added during production. 1979 Clin. Allergy pmid:421339
Dhopeshwarkar GA and Subramanian C Lipogenesis in the developing brain: utilization of radioactive leucine, isoleucine, octanoic acid and beta-hydroxybutyric acid. 1979 Lipids pmid:423709
Hainaut J et al. Differentiation of antilymphocytic antibodies by analytical ion exchange chromatography: the effect of caprylic acid. 1974 Biomedicine pmid:4433656
Tanner GA et al. Excretion of phenol red by the Necturus kidney. 1979 Am. J. Physiol. pmid:443381
Miller TB Cardiac performance of isolated perfused hearts from alloxan diabetic rats. 1979 Am. J. Physiol. pmid:443443
Debeer LJ et al. Effects of octanoate and oleate on energy metabolism in the perfused rat liver. 1974 Eur. J. Biochem. pmid:4434997
Lemieux G et al. Effect of fluoroacetate on the inhibitory action of ketone bodies and fatty acids on renal ammoniagenesis. 1979 Am. J. Physiol. pmid:464062
Strong CR and Dils R Fatty acid biosynthesis in rabbit mammary gland during pregnancy and early lactation. 1972 Biochem. J. pmid:4643704
Sheikh MI Renal handling of phenol red. I. A comparative study on the accumulation of phenol red and p-aminohippurate in rabbit kidney tubules in vitro. 1972 J. Physiol. (Lond.) pmid:4647268
Aurousseau B and de Groot L [Effect of caprylic acid on metabolism of other fatty acids in the growing rat]. 1972 Ann Biol Anim Biochim Biophys pmid:4667618
Kabara JJ et al. Fatty acids and derivatives as antimicrobial agents. 1972 Antimicrob. Agents Chemother. pmid:4670656
Spydevold O The effect of octanoate and palmitate on the metabolism of valine in perfused hindquarter of rat. 1979 Eur. J. Biochem. pmid:467425
Morrow RJ et al. Functional utilization of palmitate, octanoate, and glucose by the isolated rat heart. 1973 Proc. Soc. Exp. Biol. Med. pmid:4683244
Stewart HB et al. Intermediates in fatty acid oxidation. 1973 Biochem. J. pmid:4722901