octanoic acid

octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.

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Introduction

To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with octanoic acid?

octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with octanoic acid

MeSH term MeSH ID Detail
Insulin Resistance D007333 99 associated lipids
Jaundice, Neonatal D007567 7 associated lipids
Kidney Diseases D007674 29 associated lipids
Lipid Metabolism, Inborn Errors D008052 26 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Liver Cirrhosis, Experimental D008106 36 associated lipids
Malocclusion D008310 3 associated lipids
Memory Disorders D008569 33 associated lipids
Metabolism, Inborn Errors D008661 46 associated lipids
Obesity D009765 29 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with octanoic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with octanoic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with octanoic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with octanoic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with octanoic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with octanoic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with octanoic acid

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Authors Title Published Journal PubMed Link
Cordes AA et al. Selective domain stabilization as a strategy to reduce human serum albumin-human granulocyte colony stimulating factor aggregation rate. 2012 J Pharm Sci pmid:22422106
Vazquez-Cruz MA et al. Effect of maturity stage and storage on flavor compounds and sensory description of berrycactus (Myrtillocactus geometrizans). 2012 J. Food Sci. pmid:22429085
Wlaź P et al. Anticonvulsant profile of caprylic acid, a main constituent of the medium-chain triglyceride (MCT) ketogenic diet, in mice. 2012 Neuropharmacology pmid:22210332
Li J et al. Biodegradable thermosensitive hydrogel for SAHA and DDP delivery: therapeutic effects on oral squamous cell carcinoma xenografts. 2012 PLoS ONE pmid:22529899
Kim JW Could carbon breath test measurement accurately reflect gastric emptying of liquid nutrient meal in the critically ill patients? (Gut 2011;60:1336-1343). 2012 J Neurogastroenterol Motil pmid:22523735
Morais V and Massaldi H A model mechanism for protein precipitation by caprylic acid: application to plasma purification. 2012 Jan-Feb Biotechnol. Appl. Biochem. pmid:22332745
Zimmermann S et al. Screening and HPLC-Based Activity Profiling for New Antiprotozoal Leads from European Plants. 2012 Jan-Mar Sci Pharm pmid:22396915
Liu P et al. Membrane stress caused by octanoic acid in Saccharomyces cerevisiae. 2013 Appl. Microbiol. Biotechnol. pmid:23435986
Morrill KM et al. Estimate of serum immunoglobulin G concentration using refractometry with or without caprylic acid fractionation. 2013 J. Dairy Sci. pmid:23664346
Fonseca CR et al. Storage of refrigerated raw goat milk affecting the quality of whole milk powder. 2013 J. Dairy Sci. pmid:23664351
Costello PJ et al. Synthesis of fruity ethyl esters by acyl coenzyme A: alcohol acyltransferase and reverse esterase activities in Oenococcus oeni and Lactobacillus plantarum. 2013 J. Appl. Microbiol. pmid:23216623
Brun AC et al. Nissen fundoplication in children with cerebral palsy: influence on rate of gastric emptying and postprandial symptoms in relation to protein source in caloric liquid meals. 2013 Clin Nutr pmid:23196118
Midelfort KS et al. Redesigning and characterizing the substrate specificity and activity of Vibrio fluvialis aminotransferase for the synthesis of imagabalin. 2013 Protein Eng. Des. Sel. pmid:23012440
Librán-Pérez M et al. Response of hepatic lipid and glucose metabolism to a mixture or single fatty acids: Possible presence of fatty acid-sensing mechanisms. 2013 Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. pmid:23010243
Librán-Pérez M et al. Oleic acid and octanoic acid sensing capacity in rainbow trout Oncorhynchus mykiss is direct in hypothalamus and Brockmann bodies. 2013 PLoS ONE pmid:23533628
Librán-Pérez M et al. In vitro response of putative fatty acid-sensing systems in rainbow trout liver to increased levels of oleate or octanoate. 2013 Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. pmid:23542747
Creedon CT et al. Assessment of gastric emptying in non-obese diabetic mice using a [13C]-octanoic acid breath test. 2013 J Vis Exp pmid:23542813
Shilling M et al. Antimicrobial effects of virgin coconut oil and its medium-chain fatty acids on Clostridium difficile. 2013 J Med Food pmid:24328700
Hungate EA et al. A locus in Drosophila sechellia affecting tolerance of a host plant toxin. 2013 Genetics pmid:24037270
Kursu VA et al. Defects in mitochondrial fatty acid synthesis result in failure of multiple aspects of mitochondrial biogenesis in Saccharomyces cerevisiae. 2013 Mol. Microbiol. pmid:24102902