| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hepatic Encephalopathy | D006501 | 9 associated lipids |
| Hemorrhage | D006470 | 15 associated lipids |
| Hemolysis | D006461 | 131 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Giardiasis | D005873 | 3 associated lipids |
| Gastrointestinal Diseases | D005767 | 20 associated lipids |
| Flatulence | D005414 | 1 associated lipids |
| Epilepsy | D004827 | 35 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Dyspepsia | D004415 | 5 associated lipids |
octanoic acid
octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.
Cross Reference
Introduction
To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with octanoic acid?
octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with octanoic acid
PubChem Associated disorders and diseases
What pathways are associated with octanoic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with octanoic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with octanoic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with octanoic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with octanoic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with octanoic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with octanoic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Yoshida Y et al. | Effect of salicylic acid on mitochondrial-peroxisomal fatty acid catabolism. | 1988 | Pediatr. Res. | pmid:3353181 |
| Olubadewo JO et al. | Effects of 8-N,N-diethylamino-octyl-3,4,5-trimethoxybenzoate (TMB-8) HCl and verapamil on the metabolism of free fatty acid by hepatocytes. | 1988 | Biochem. Pharmacol. | pmid:3358779 |
| Wu G and Thompson JR | Effect of pyruvate, octanoate and glucose on leucine degradation in skeletal muscle from fed and fasted chicks. | 1988 | Int. J. Biochem. | pmid:3371527 |
| Zieve L et al. | Hepatic failure toxins depress liver regenerative enzymes after periportal injury with allyl alcohol in the rat. | 1988 | J. Lab. Clin. Med. | pmid:3373115 |
| Fellenberg AJ and Pollard AC | A rapid and sensitive gas-liquid chromatographic procedure for the micro determination of sodium valproate (sodium di-N-propylacetate) in plasma or serum. | 1977 | Clin. Chim. Acta | pmid:338203 |
| Matsuzaki K et al. | Inhibition of cortical collecting tubule chloride transport by organic acids. | 1988 | J. Clin. Invest. | pmid:3392216 |
| Ogden JR and Leung K | Purification of murine monoclonal antibodies by caprylic acid. | 1988 | J. Immunol. Methods | pmid:3397551 |
| Allison F et al. | The oxidation of octanoic acid by cultured amniotic fluid cells: the effect of cell type and passage number. | 1988 | Prenat. Diagn. | pmid:3405975 |
| Malewiak MI et al. | Oleate metabolism and endogenous triacylglycerol hydrolysis in isolated hepatocytes from rats fed a high-fat diet. | 1988 May-Jun | Diabete Metab | pmid:3410152 |
| Kajii H et al. | Fluorescence study of the membrane-perturbing action of sodium caprylate as related to promotion of drug absorption. | 1988 | J Pharm Sci | pmid:3411458 |
| Foxworthy PS and Eacho PI | Inhibition of hepatic fatty acid oxidation at carnitine palmitoyltransferase I by the peroxisome proliferator 2-hydroxy-3-propyl-4-[6-(tetrazol-5-yl) hexyloxy]acetophenone. | 1988 | Biochem. J. | pmid:3415664 |
| Handler JA and Thurman RG | Catalase-dependent ethanol oxidation in perfused rat liver. Requirement for fatty-acid-stimulated H2O2 production by peroxisomes. | 1988 | Eur. J. Biochem. | pmid:3416882 |
| Jenkins DL and Griffith OW | Antiketogenic and hypoglycemic effects of aminocarnitine and acylaminocarnitines. | 1986 | Proc. Natl. Acad. Sci. U.S.A. | pmid:3455765 |
| Watford M et al. | The regulation of glutamine and ketone-body metabolism in the small intestine of the long-term (40-day) streptozotocin-diabetic rat. | 1987 | Biochem. J. | pmid:3473986 |
| Trauner DA and Adams HR | Effects of therapeutic agents in a rabbit model of Reye syndrome. | 1987 May-Jun | Pediatr. Neurol. | pmid:3508061 |
| Rösen P et al. | Myocardial performance and metabolism in non-ketotic, diabetic rat hearts: myocardial function and metabolism in vivo and in the isolated perfused heart under the influence of insulin and octanoate. | 1986 Nov-Dec | Basic Res. Cardiol. | pmid:3545178 |
| Thomson AB | The level of dietary protein and carbohydrate has a different effect on intestinal uptake of hexoses and lipids in rabbits with an ileal resection than in those with an intact intestinal tract. | 1987 | Can. J. Physiol. Pharmacol. | pmid:3567736 |
| Bennett MJ et al. | Prenatal diagnosis of medium-chain acyl-coenzyme A dehydrogenase deficiency. | 1987 | Prenat. Diagn. | pmid:3575262 |
| Lambin P and Debbia M | [IgG4 levels in polyvalent immunoglobulins and immunoglobulins prepared by precipitation with caprylic acid]. | 1986 Oct-Nov | Rev. Fr. Transfus. Immunohematol. | pmid:3576044 |
| Jandacek RJ et al. | The rapid hydrolysis and efficient absorption of triglycerides with octanoic acid in the 1 and 3 positions and long-chain fatty acid in the 2 position. | 1987 | Am. J. Clin. Nutr. | pmid:3578095 |
| Pahl-Wostl C and Seelig J | Ketogenesis in the living rat followed by 13C-NMR spectroscopy. Infusion of [1,3-13C]octanoate. | 1987 | Biol. Chem. Hoppe-Seyler | pmid:3593540 |
| Reik LM et al. | A simple, non-chromatographic purification procedure for monoclonal antibodies. Isolation of monoclonal antibodies against cytochrome P450 isozymes. | 1987 | J. Immunol. Methods | pmid:3598193 |
| Cistola DP et al. | Carbon 13 NMR studies of saturated fatty acids bound to bovine serum albumin. I. The filling of individual fatty acid binding sites. | 1987 | J. Biol. Chem. | pmid:3611099 |
| Cistola DP et al. | Carbon 13 NMR studies of saturated fatty acids bound to bovine serum albumin. II. Electrostatic interactions in individual fatty acid binding sites. | 1987 | J. Biol. Chem. | pmid:3611100 |
| Halestrap AP | The regulation of the oxidation of fatty acids and other substrates in rat heart mitochondria by changes in the matrix volume induced by osmotic strength, valinomycin and Ca2+. | 1987 | Biochem. J. | pmid:3663110 |
| Allen PC | The effect of Eimeria acervulina infection on hearts of young broiler chicks. | 1987 Jul-Sep | Avian Dis. | pmid:3675428 |
| Cole SG et al. | Cholesteryl octanoate breath test. Preliminary studies on a new noninvasive test of human pancreatic exocrine function. | 1987 | Gastroenterology | pmid:3678753 |
| el-Aleem SA and Schulz H | Evaluation of inhibitors of fatty acid oxidation in rat myocytes. | 1987 | Biochem. Pharmacol. | pmid:3689454 |
| Yoshioka M et al. | Malabsorption of long-chain fatty acid in cholera toxin-induced secretory diarrhea. | 1986 | Dig. Dis. Sci. | pmid:3698768 |
| Fatania HR et al. | Modulation of pyruvate dehydrogenase kinase activity in cultured hepatocytes by glucagon and n-octanoate. | 1986 | Biochem. J. | pmid:3707545 |
| Letko G and Halangk W | Effect of improved hydrogen supply on energy state, ureogenesis and gluconeogenesis in isolated hepatocytes. | 1986 | Biomed. Biochim. Acta | pmid:3707550 |
| Okita M et al. | Plasma level of branched chain alpha-amino acids following its alpha-keto acid administration to rats. | 1986 | J. Nutr. Sci. Vitaminol. | pmid:3712111 |
| Matsumura T et al. | O2 uptake in periportal and pericentral regions of liver lobule in perfused liver. | 1986 | Am. J. Physiol. | pmid:3717341 |
| Amendt BA and Rhead WJ | The multiple acyl-coenzyme A dehydrogenation disorders, glutaric aciduria type II and ethylmalonic-adipic aciduria. Mitochondrial fatty acid oxidation, acyl-coenzyme A dehydrogenase, and electron transfer flavoprotein activities in fibroblasts. | 1986 | J. Clin. Invest. | pmid:3722376 |
| Beuers U et al. | Control of ketogenesis in the perfused rat liver by the sympathetic innervation. | 1986 | Eur. J. Biochem. | pmid:3732268 |
| Spector R | Development and characterization of pantothenic acid transport in brain. | 1986 | J. Neurochem. | pmid:3734794 |
| Hulshoff A and Roseboom H | Determination of valproic acid (di-N-propyl acetic acid) in plasma by gas-liquid chromatography with pre-column butylation. | 1979 | Clin. Chim. Acta | pmid:373927 |
| Lysiak W et al. | Quantitation of the efflux of acylcarnitines from rat heart, brain, and liver mitochondria. | 1986 | J. Biol. Chem. | pmid:3759988 |
| Higaki K et al. | Effect of medium-chain glycerides (MGK) on the intestinal absorption and the hepatobiliary transport of bromthymol blue. | 1986 | J. Pharmacobio-dyn. | pmid:3761141 |
| Nomura T et al. | Effects of vasopressin, angiotensin II and phenylephrine on hepatic ketogenesis and fatty acid synthesis. | 1986 | Jpn. J. Pharmacol. | pmid:3773344 |
| Garner CW and Behal FJ | Effect of pH on substrate and inhibitor kinetic constants of human liver alanine aminopeptidase. Evidence for two ionizable active center groups. | 1975 | Biochemistry | pmid:38 |
| Clouet P et al. | Study of some factors controlling fatty acid oxidation in liver mitochondria of obese Zucker rats. | 1986 | Biochem. J. | pmid:3800970 |
| McKinney MM and Parkinson A | A simple, non-chromatographic procedure to purify immunoglobulins from serum and ascites fluid. | 1987 | J. Immunol. Methods | pmid:3805742 |
| Komura S and Kurahashi K | Biosynthesis of polymyxin E by a cell-free enzyme system. IV. Acylation of enzyme-bound L-2,4-diaminobutyric acid. | 1985 | J. Biochem. | pmid:3861608 |
| Trauner DA and Garrett RS | Effect of octanoate injection on rat blood-brain barrier. | 1985 Jan-Feb | Pediatr. Neurol. | pmid:3880386 |
| Trauner DA and de la Torre JC | Effect of octanoate on blood-brain barrier permeability using L-dopa as a marker. | 1985 Jul-Aug | Pediatr. Neurol. | pmid:3880408 |
| Trice JE and Trauner DA | Alterations in serum glucose and hepatic glycogen concentrations during octanoate administration in rabbits. | 1985 Sep-Oct | Pediatr. Neurol. | pmid:3880415 |
| Beaufrere B et al. | Apparent decreased oxidation and turnover of leucine during infusion of medium-chain triglycerides. | 1985 | Am. J. Physiol. | pmid:3895976 |
| Schmidt FH et al. | A new inhibitor of the long-chain fatty acid transfer across the mitochondrial membrane: 2-(3-methylcinnamylhydrazono)-propionate (BM 42.304). | 1985 | Life Sci. | pmid:3917523 |
| Eanes WF et al. | Targeted selection experiments and enzyme polymorphism: negative evidence for octanoate selection at the G6PD locus in Drosophila melanogaster. | 1985 | Genetics | pmid:3918918 |