octanoic acid

octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.

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Introduction

To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with octanoic acid?

octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with octanoic acid

MeSH term MeSH ID Detail
Biliary Fistula D001658 13 associated lipids
Campylobacter Infections D002169 13 associated lipids
Hypertension, Portal D006975 12 associated lipids
Amyotrophic Lateral Sclerosis D000690 11 associated lipids
Insulin Resistance D007333 99 associated lipids
Diabetic Neuropathies D003929 5 associated lipids
Critical Illness D016638 13 associated lipids
Endotoxemia D019446 27 associated lipids
Memory Disorders D008569 33 associated lipids
Cholestasis, Extrahepatic D001651 7 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with octanoic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with octanoic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with octanoic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with octanoic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with octanoic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with octanoic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with octanoic acid

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Authors Title Published Journal PubMed Link
Habeeb AF and Francis RD Preparation of human immunoglobulin by caprylic acid precipitation. 1984 Prep. Biochem. pmid:6718324
Allison F et al. The oxidation of octanoic acid by cultured amniotic fluid cells: the effect of cell type and passage number. 1988 Prenat. Diagn. pmid:3405975
Bennett MJ et al. Prenatal diagnosis of medium-chain acyl-coenzyme A dehydrogenase deficiency. 1987 Prenat. Diagn. pmid:3575262
Tien ES et al. Examination of Ligand-Dependent Coactivator Recruitment by Peroxisome Proliferator-Activated Receptor-alpha (PPARalpha). 2006 PPAR Res pmid:17259669
Solis de Los Santos F et al. Caprylic acid supplemented in feed reduces enteric Campylobacter jejuni colonization in ten-day-old broiler chickens. 2008 Poult. Sci. pmid:18340004
Bhanushali JK et al. Simple method to purify chicken immunoglobulin G. 1994 Poult. Sci. pmid:7937478
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Vavricka CJ et al. Structural and functional analysis of laninamivir and its octanoate prodrug reveals group specific mechanisms for influenza NA inhibition. 2011 PLoS Pathog. pmid:22028647
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Eagle RA et al. Cellular expression, trafficking, and function of two isoforms of human ULBP5/RAET1G. 2009 PLoS ONE pmid:19223974
Takahashi K et al. Nematode homologue of PQBP1, a mental retardation causative gene, is involved in lipid metabolism. 2009 PLoS ONE pmid:19119319
Arora T et al. Roux-en-Y Gastric Bypass Surgery Induces Early Plasma Metabolomic and Lipidomic Alterations in Humans Associated with Diabetes Remission. 2015 PLoS ONE pmid:25946120
Takatani-Nakase T et al. Transcutaneous immunization system using a hydrotropic formulation induces a potent antigen-specific antibody response. 2012 PLoS ONE pmid:23110149