octanoic acid

octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.

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Introduction

To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with octanoic acid?

octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with octanoic acid

MeSH term MeSH ID Detail
Biliary Fistula D001658 13 associated lipids
Campylobacter Infections D002169 13 associated lipids
Hypertension, Portal D006975 12 associated lipids
Amyotrophic Lateral Sclerosis D000690 11 associated lipids
Insulin Resistance D007333 99 associated lipids
Diabetic Neuropathies D003929 5 associated lipids
Critical Illness D016638 13 associated lipids
Endotoxemia D019446 27 associated lipids
Memory Disorders D008569 33 associated lipids
Cholestasis, Extrahepatic D001651 7 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with octanoic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with octanoic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with octanoic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with octanoic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with octanoic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with octanoic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with octanoic acid

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Authors Title Published Journal PubMed Link
Guidry AJ and O'Brien CN A method for measuring specific antibodies in bovine lacteal secretions during the nonlactating period. 1996 J. Dairy Sci. pmid:8792284
Godet MC et al. Inclusion/exclusion of fatty acids in amylose complexes as a function of the fatty acid chain length. 1995 Int. J. Biol. Macromol. pmid:8789347
Zhou YP et al. Inhibitory effects of fatty acids on glucose-regulated B-cell function: association with increased islet triglyceride stores and altered effect of fatty acid oxidation on glucose metabolism. 1996 Metab. Clin. Exp. pmid:8769356
Barron JT et al. Substrate-dependent alteration in O2 consumption and energy metabolism in vascular smooth muscle. 1996 Am. J. Physiol. pmid:8764234
Lin X et al. Acetate represents a major product of heptanoate and octanoate beta-oxidation in hepatocytes isolated from neonatal piglets. 1996 Biochem. J. pmid:8761477
Sherrington EJ et al. Lack of effect of different dietary saturated fatty acids on adipose tissue deposition in the rat. 1996 Biochem. Soc. Trans. pmid:8736816
Planelles D et al. A new, fast, and simple DNA extraction method for HLA and VNTR genotyping by PCR amplification. 1996 J. Clin. Lab. Anal. pmid:8731498
Sheikh MI et al. On the mechanism of p-piperidyl and p-benzyl sulfamyl benzoic acids transport by renal tissue. 1978 Arch. Int. Physiol. Biochim. pmid:87158
Tomita GM et al. Antigenic crossreactivity and lipopolysaccharide neutralization properties of bovine immunoglobulin G. 1995 J. Dairy Sci. pmid:8675757
Cheruvallath VK et al. The effect of octanoic acid on the binding of the enantiomers of ibuprofen and naproxen to human serum albumin: a chromatographic implication. 1996 Pharm. Res. pmid:8668670
Evtodienko VY et al. Effect of the alkyl chain length of monocarboxylic acid on the permeation through bilayer lipid membranes. 1996 Biochim. Biophys. Acta pmid:8664324
Perri F et al. Gastric emptying and Helicobacter pylori infection in duodenal ulcer disease. 1996 Dig. Dis. Sci. pmid:8617116
Murphy MG et al. Abnormalities in hepatic fatty-acid metabolism in a surfactant/influenza B virus mouse model for acute encephalopathy. 1996 Biochim. Biophys. Acta pmid:8611661
Carrella M and Dietschy JM Comparison of the effects of cholic acid and chenic acid feeding on rates of cholesterol synthesis in the liver of the rat. 1977 Am J Dig Dis pmid:857658
Lamas JA et al. Caprylic acid, a medium chain saturated fatty acid, inhibits the sodium inward current in neuroglioma (NG108-15) cells. 1995 Neurosci. Lett. pmid:8552316
Büllesbach EE and Schwabe C Structural contribution of the A-chain loop in relaxin. 1995 Sep-Oct Int. J. Pept. Protein Res. pmid:8537177
Kuge Y et al. Brain uptake and metabolism of [1-11C]octanoate in rats: pharmacokinetic basis for its application as a radiopharmaceutical for studying brain fatty acid metabolism. 1995 Ann Nucl Med pmid:8534586
Vandenvelde C et al. Suppression of the inhibitory effect of denatured albumin on the polymerase chain reaction by sodium octanoate: application to routine clinical detection of hepatitis B virus at its infectivity threshold in serum. 1993 J. Virol. Methods pmid:8514843
Ghoos YF et al. Measurement of gastric emptying rate of solids by means of a carbon-labeled octanoic acid breath test. 1993 Gastroenterology pmid:8500721
Liu MJ and Pollack GM Pharmacokinetics and pharmacodynamics of valproate analogs in rats. II. Pharmacokinetics of octanoic acid, cyclohexanecarboxylic acid, and 1-methyl-1-cyclohexanecarboxylic acid. 1993 Biopharm Drug Dispos pmid:8499583