octanoic acid

octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.

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Introduction

To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with octanoic acid?

octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with octanoic acid

MeSH term MeSH ID Detail
Biliary Fistula D001658 13 associated lipids
Campylobacter Infections D002169 13 associated lipids
Hypertension, Portal D006975 12 associated lipids
Amyotrophic Lateral Sclerosis D000690 11 associated lipids
Insulin Resistance D007333 99 associated lipids
Diabetic Neuropathies D003929 5 associated lipids
Critical Illness D016638 13 associated lipids
Endotoxemia D019446 27 associated lipids
Memory Disorders D008569 33 associated lipids
Cholestasis, Extrahepatic D001651 7 associated lipids
Per page 10 20 50 100 | Total 73

PubChem Associated disorders and diseases

What pathways are associated with octanoic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with octanoic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with octanoic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with octanoic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with octanoic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with octanoic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with octanoic acid

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Authors Title Published Journal PubMed Link
Macko T et al. Elution behavior of polyethylene in polar mobile phases on a non-polar sorbent. 2003 J Chromatogr A pmid:12647822
Trejo SR et al. Evaluation of virus and prion reduction in a new intravenous immunoglobulin manufacturing process. 2003 Vox Sang. pmid:12670366
Lebing W et al. Properties of a new intravenous immunoglobulin (IGIV-C, 10%) produced by virus inactivation with caprylate and column chromatography. 2003 Vox Sang. pmid:12670368
Ballow M et al. Pharmacokinetics and tolerability of a new intravenous immunoglobulin preparation, IGIV-C, 10% (Gamunex, 10%). 2003 Vox Sang. pmid:12670369
Theakston RD et al. Report of a WHO workshop on the standardization and control of antivenoms. 2003 Toxicon pmid:12676433
Mori S et al. Rat organic anion transporter 3 (rOAT3) is responsible for brain-to-blood efflux of homovanillic acid at the abluminal membrane of brain capillary endothelial cells. 2003 J. Cereb. Blood Flow Metab. pmid:12679720
van de Casteele M et al. Oxidative breakdown of octanoic acid is maintained in patients with cirrhosis despite advanced disease. 2003 Neurogastroenterol. Motil. pmid:12680910
Dobbins JW and Binder HJ Effect of bile salts and fatty acids on the colonic absorption of oxalate. 1976 Gastroenterology pmid:1269869
Takenaka T et al. Fatty acids as an energy source for the operation of axoplasmic transport. 2003 Brain Res. pmid:12711076
Iwasaki Y et al. Reduced adhesion of blood cells to biodegradable polymers by introducing phosphorylcholine moieties. 2003 J Biomed Mater Res A pmid:12734808
Crane J et al. Triacylglycerols determine the unusual storage physiology of Cuphea seed. 2003 Planta pmid:12743824
Hamel FG et al. In vitro inhibition of insulin-degrading enzyme by long-chain fatty acids and their coenzyme A thioesters. 2003 Endocrinology pmid:12746301
Li C et al. Covalent binding of 2-phenylpropionyl-S-acyl-CoA thioester to tissue proteins in vitro. 2003 Drug Metab. Dispos. pmid:12756204
Aiston S et al. Glucose 6-phosphate regulates hepatic glycogenolysis through inactivation of phosphorylase. 2003 Diabetes pmid:12765941
Oettl K et al. An apparent decrease in cholesterol biosynthesis in peroxisomal-defective Chinese hamster ovary cells is related to impaired mitochondrial oxidation. 2003 Biochem. Biophys. Res. Commun. pmid:12767923
Zahn A et al. Measurement of gastric emptying by 13C-octanoic acid breath test versus scintigraphy in diabetics. 2003 Z Gastroenterol pmid:12772050
Claessens YE et al. Bench-to-bedside review: severe lactic acidosis in HIV patients treated with nucleoside analogue reverse transcriptase inhibitors. 2003 Crit Care pmid:12793872
Winiarska K et al. Relationship between gluconeogenesis and glutathione redox state in rabbit kidney-cortex tubules. 2003 Metab. Clin. Exp. pmid:12800101
Iwahashi H et al. The formation of the 7-carboxyheptyl radical from 13-hydroperoxy-9,11-octadecadienoic acid catalyzed by hemoglobin and myoglobin under anaerobic conditions. 2003 J. Biochem. pmid:12801921
Han J et al. Medium-chain oil reduces fat mass and down-regulates expression of adipogenic genes in rats. 2003 Obes. Res. pmid:12805394
Cai Q et al. Synthesis and characterization of biodegradable polylactide-grafted dextran and its application as compatilizer. 2003 Biomaterials pmid:12809784
Zhou S et al. Biodegradable poly(epsilon-caprolactone)-poly(ethylene glycol) block copolymers: characterization and their use as drug carriers for a controlled delivery system. 2003 Biomaterials pmid:12809785
Kudo N and Kawashima Y Toxicity and toxicokinetics of perfluorooctanoic acid in humans and animals. 2003 J Toxicol Sci pmid:12820537
Piette V et al. Enantiomeric separation of N-protected amino acids by non-aqueous capillary electrophoresis with dimeric forms of quinine and quinidine derivatives serving as chiral selectors. 2002 J Chromatogr A pmid:12831205
Lee SH et al. Elastic biodegradable poly(glycolide-co-caprolactone) scaffold for tissue engineering. 2003 J Biomed Mater Res A pmid:12833428
Kuge Y et al. Characteristic brain distribution of 1-(14)C-octanoate in a rat model of focal cerebral ischemia in comparison with those of (123)I-IMP and (123)I-iomazenil. 2003 J. Nucl. Med. pmid:12843233
Ebert D et al. Energy contribution of octanoate to intact rat brain metabolism measured by 13C nuclear magnetic resonance spectroscopy. 2003 J. Neurosci. pmid:12843297
Randriamahefa S et al. Fourier transform infrared spectroscopy for screening and quantifying production of PHAs by Pseudomonas grown on sodium octanoate. 2003 Jul-Aug Biomacromolecules pmid:12857097
Ho TS et al. Liquid-phase microextraction of hydrophilic drugs by carrier-mediated transport. 2003 J Chromatogr A pmid:12862372
Walton ME et al. Octanoate oxidation measured by 13C-NMR spectroscopy in rat skeletal muscle, heart, and liver. 2003 J. Appl. Physiol. pmid:12882988
de Assis DR et al. Evidence that antioxidants prevent the inhibition of Na+,K(+)-ATPase activity induced by octanoic acid in rat cerebral cortex in vitro. 2003 Neurochem. Res. pmid:12892042
Boushaba R et al. Kinetics of whole serum and prepurified IgG digestion by pepsin for F(ab')2 manufacture. Biotechnol. Prog. pmid:12892479
Wang Z and Zhang Q [Study on pulmonary delivery system of salmon calcitonin in rats]. 2003 Beijing Da Xue Xue Bao pmid:12914259
Massillon D et al. Regulation of glucose-6-phosphatase gene expression in cultured hepatocytes and H4IIE cells by short-chain fatty acids: role of hepatic nuclear factor-4alpha. 2003 J. Biol. Chem. pmid:12915406
Lu XY et al. Production of poly(3-hydroxybutyrate- co-3-hydroxyhexanoate) with flexible 3-hydroxyhexanoate content in Aeromonas hydrophila CGMCC 0911. 2004 Appl. Microbiol. Biotechnol. pmid:12920488
Dieterle F et al. Urinary nucleosides as potential tumor markers evaluated by learning vector quantization. 2003 Artif Intell Med pmid:12927336
Guy JE et al. The structure of an alcohol dehydrogenase from the hyperthermophilic archaeon Aeropyrum pernix. 2003 J. Mol. Biol. pmid:12927540
Vincent G et al. Differential modulation of citrate synthesis and release by fatty acids in perfused working rat hearts. 2004 Am. J. Physiol. Heart Circ. Physiol. pmid:12933348
Johnston A et al. Low pH, caprylate incubation as a second viral inactivation step in the manufacture of albumin. Parametric and validation studies. 2003 Biologicals pmid:12935811
Hiraoka T et al. Effects of oral stimulation with fats on the cephalic phase of pancreatic enzyme secretion in esophagostomized rats. 2003 Physiol. Behav. pmid:12954413
Nakajima I et al. Growth arrest by octanoate is required for porcine preadipocyte differentiation. 2003 Biochem. Biophys. Res. Commun. pmid:12963048
Richards JG et al. Palmitate movement across red and white muscle membranes of rainbow trout. 2004 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:12969874
Kaiya H et al. Peptide purification, complementary deoxyribonucleic acid (DNA) and genomic DNA cloning, and functional characterization of ghrelin in rainbow trout. 2003 Endocrinology pmid:12970156
Giron D et al. Analysis of mono-, di- and triglycerides in pharmaceutical excipients by capillary supercritical fluid chromatography. 1992 Oct-Dec J Pharm Biomed Anal pmid:1298389
REICH WJ et al. The treatment of monilial vaginitis with caprylic acid. 1953 Am. J. Obstet. Gynecol. pmid:13016687
GEYER RP et al. Effect of pyruvate on octanoate metabolism as influenced by potassium and lithium. 1953 J. Biol. Chem. pmid:13084632
BROWN GW et al. On the unequal conversion of the carboxyl and seventh carbons of octanoate to CO2 by liver slices. 1954 Arch. Biochem. Biophys. pmid:13159319
CHAPMAN DD et al. A comparison of the oxidation of octanoate-1-C14, -7-C14, and butyrate-1-C14 by neoplastic and normal mouse tissues. 1954 Cancer Res. pmid:13160966
Stace PB et al. Cyclic AMP and free fatty acids in the longer-term regulation of pyruvate dehydrogenase kinase in rat soleus muscle. 1992 Biochim. Biophys. Acta pmid:1319745
LOSSOW WJ et al. The action of insulin in sparing fatty acid oxidation: a study with palmitic acid-1-C14 and octanoate-1-C14. 1956 J. Biol. Chem. pmid:13331942