octanoic acid

octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.

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Introduction

To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with octanoic acid?

octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with octanoic acid

MeSH term MeSH ID Detail
Biliary Fistula D001658 13 associated lipids
Campylobacter Infections D002169 13 associated lipids
Hypertension, Portal D006975 12 associated lipids
Amyotrophic Lateral Sclerosis D000690 11 associated lipids
Insulin Resistance D007333 99 associated lipids
Diabetic Neuropathies D003929 5 associated lipids
Critical Illness D016638 13 associated lipids
Endotoxemia D019446 27 associated lipids
Memory Disorders D008569 33 associated lipids
Cholestasis, Extrahepatic D001651 7 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with octanoic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with octanoic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with octanoic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with octanoic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with octanoic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with octanoic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with octanoic acid

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Authors Title Published Journal PubMed Link
Ballistreri A et al. Biosynthesis and structural characterization of medium-chain-length poly(3-hydroxyalkanoates) produced by Pseudomonas aeruginosa from fatty acids. 2001 Int. J. Biol. Macromol. pmid:11518582
Jahnke LL and Diggs K Evidence for the synthesis of the multi-positional isomers of monounsaturated fatty acid in Methylococcus capsusatus by the anaerobic pathway. 1989 FEMS Microbiol. Lett. pmid:11542184
Kaiya H et al. Bullfrog ghrelin is modified by n-octanoic acid at its third threonine residue. 2001 J. Biol. Chem. pmid:11546772
Ritz MA et al. Delayed gastric emptying in ventilated critically ill patients: measurement by 13 C-octanoic acid breath test. 2001 Crit. Care Med. pmid:11546976
Matsumoto M et al. Structure-activity relationship of ghrelin: pharmacological study of ghrelin peptides. 2001 Biochem. Biophys. Res. Commun. pmid:11549267
Robinson MK Intra-individual variations in acute and cumulative skin irritation responses. 2001 Contact Derm. pmid:11553116
MacGowan GA et al. High calcium and dobutamine positive inotropy in the perfused mouse heart: myofilament calcium responsiveness, energetic economy, and effects of protein kinase C inhibition. 2001 BMC Physiol. pmid:11553322
Longnus SL et al. Regulation of myocardial fatty acid oxidation by substrate supply. 2001 Am. J. Physiol. Heart Circ. Physiol. pmid:11557544
Randich A et al. Jejunal or portal vein infusions of lipids increase hepatic vagal afferent activity. 2001 Neuroreport pmid:11568645
Rimmer DA et al. Determination of organo-zinc based fungicides in timber treatments employing gas chromatographic analysis with mass selective detection and/or inductively coupled plasma atomic emission spectroscopy. 2001 J Chromatogr A pmid:11587339
Kanamoto N et al. Substantial production of ghrelin by a human medullary thyroid carcinoma cell line. 2001 J. Clin. Endocrinol. Metab. pmid:11600575
Wyse CA et al. The(13)C-octanoic acid breath test for detection of effects of meal composition on the rate of solid-phase gastric emptying in ponies. 2001 Res. Vet. Sci. pmid:11666152
Jung KY et al. Characterization of ochratoxin A transport by human organic anion transporters. 2001 Life Sci. pmid:11669456
Hlongwane C et al. Comparative quantitative fatty acid analysis of triacylglycerols using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry and gas chromatography. 2001 Rapid Commun. Mass Spectrom. pmid:11675670
Abdel-Hamid ME et al. Stability study of the anticonvulsant enaminone (E118) using HPLC and LC-MS. 2002 J Pharm Biomed Anal pmid:11682230
Frederich M and Balschi JA The relationship between AMP-activated protein kinase activity and AMP concentration in the isolated perfused rat heart. 2002 J. Biol. Chem. pmid:11707445
Chung DM et al. Intracellular degradation of two structurally different polyhydroxyalkanoic acids accumulated in Pseudomonas putida and Pseudomonas citronellolis from mixtures of octanoic acid and 5-phenylvaleric acid. 2001 Int. J. Biol. Macromol. pmid:11718820
Kawaguchi T et al. Mechanism for fatty acid "sparing" effect on glucose-induced transcription: regulation of carbohydrate-responsive element-binding protein by AMP-activated protein kinase. 2002 J. Biol. Chem. pmid:11724780
Grellet S et al. An associated process for the purification of immuno globulin G, catalase, superoxide dismutase and albumin from haemolysed human placenta blood. 2001 Biotechnol. Appl. Biochem. pmid:11730480
Sleboda J et al. Palmitate oxidation in rat hepatocytes is inhibited by foetal calf serum. 2001 Acta Physiol. Scand. pmid:11736689