octanoic acid

octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.

Cross Reference

Introduction

To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with octanoic acid?

octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with octanoic acid

MeSH term MeSH ID Detail
Biliary Fistula D001658 13 associated lipids
Campylobacter Infections D002169 13 associated lipids
Hypertension, Portal D006975 12 associated lipids
Amyotrophic Lateral Sclerosis D000690 11 associated lipids
Insulin Resistance D007333 99 associated lipids
Diabetic Neuropathies D003929 5 associated lipids
Critical Illness D016638 13 associated lipids
Endotoxemia D019446 27 associated lipids
Memory Disorders D008569 33 associated lipids
Cholestasis, Extrahepatic D001651 7 associated lipids
Per page 10 20 50 100 | Total 73

PubChem Associated disorders and diseases

What pathways are associated with octanoic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with octanoic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with octanoic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with octanoic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with octanoic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with octanoic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with octanoic acid

Download all related citations
Per page 10 20 50 100 | Total 2110
Authors Title Published Journal PubMed Link
Derr RF and Draves K Methanethiol metabolism in the rat. 1983 Res. Commun. Chem. Pathol. Pharmacol. pmid:6407074
Bijlsma R and Kerver JW The effect of DDT on the polymorphism at the G6pd and Pgd loci in Drosophila melanogaster. 1983 Genetics pmid:6404694
Reed WD et al. The effects of insulin and glucagon on ketone-body turnover. 1984 Biochem. J. pmid:6383348
Hansford RG Lipid oxidation by heart mitochondria from young adult and senescent rats. 1978 Biochem. J. pmid:637843
Kochel PJ et al. Effects of noncarbohydrate substrates on protein synthesis in hearts from fed and fasted rats. 1984 J. Mol. Cell. Cardiol. pmid:6374161
Bielefeld DR et al. Altered sensitivity of chronic diabetic rat heart to calcium. 1983 Am. J. Physiol. pmid:6362427
Zieve L et al. Toxicity of a fatty acid and ammonia: interactions with hypoglycemia and Krebs cycle inhibition. 1983 J. Lab. Clin. Med. pmid:6343534
Demol P and Sarles H Action of fatty acids on the exocrine pancreatic secretion of the conscious rat: further evidence for a protein pancreatic inhibitory factor. 1978 J. Physiol. (Lond.) pmid:633115
Salesse R and Garnier J Adenylate cyclase and membrane fluidity. The repressor hypothesis. 1984 Mol. Cell. Biochem. pmid:6323963
Nomura T et al. Effects of octanoate and acetate upon hepatic glycolysis and lipogenesis. 1983 Biochim. Biophys. Acta pmid:6317044
Skrede S et al. Coenzyme A in dog kidneys during hypothermic perfusion. 1983 Cryobiology pmid:6309478
Geppert EF and Elstein KH Short-term regulation of fatty acid synthesis in isolated alveolar type II cells from adult rat lung. Effects of free fatty acids and hormones. 1983 Exp. Lung Res. pmid:6305647
Nosek TM and Crosland MB Calcium-dependent proteolysis in neural tissue is activated at physiologic intracellular Ca2+ levels and inhibited by some anticonvulsants. 1983 J. Neurobiol. pmid:6298363
Salesse R et al. Modulation of adenylate cyclase activity by the physical state of pigeon erythrocyte membrane. 1. Parallel drug-induced changes in the bilayer fluidity and adenylate cyclase activity. 1982 Biochemistry pmid:6282308
Seydoux J et al. Impaired metabolic response to nerve stimulation in brown adipose tissue of hypothyroid rats. 1982 Mol. Cell. Endocrinol. pmid:6276252
Assimacopoulos-Jeannet F et al. Alterations of brown adipose tissue in genetically obese (ob/ob) mice. II. Studies of beta-adrenergic receptors and fatty acid degradation. 1982 Endocrinology pmid:6276135
Müller MJ et al. Effect of thyroid state on ketogenic capacity of the isolated perfused liver of starved rats. 1981 Biochim. Biophys. Acta pmid:6275888
Burns AH and Reddy WJ Effect of ouabain on exogenous substrate oxidation by isolated cardiac myocytes. 1981 Res. Commun. Chem. Pathol. Pharmacol. pmid:6267674
Kinnula VL and Hassinen I Effect of chronic hypoxia on hepatic triacylglycerol concentration and mitochondrial fatty acid oxidizing capacity in liver and heart. 1978 Acta Physiol. Scand. pmid:626089
Trauner DA Regional cerebral Na+K+ ATPase activity following octanoate administration. 1980 Pediatr. Res. pmid:6250122
Seydoux J et al. Brown adipose tissue metabolism in streptozotocin-diabetic rats. 1983 Endocrinology pmid:6223804
Rabinowitz JL et al. Sources of serum [14C]-octanoate in cirrhosis of the liver and hepatic encephalopathy. 1978 J. Lab. Clin. Med. pmid:621424
Claycomb WC et al. Culture of the terminally differentiated ventricular cardiac muscle cell. Characterization of exogenous substrate oxidation and the adenylate cyclase system. 1984 FEBS Lett. pmid:6201398
Guddat W and Hillger K A heat polyethylene glycol procedure as an alternative method for plasmafractionation. 1982 Folia Haematol. Int. Mag. Klin. Morphol. Blutforsch. pmid:6187637
Grill V Nutrient-induced priming of insulin and glucagon secretion. Effects of alpha-ketoisocaproic acid. 1982 Endocrinology pmid:6173206
Lemieux G et al. Relationship between the renal metabolism of glutamine, fatty acids and ketone bodies. 1977 Oct 23-26 Curr Probl Clin Biochem pmid:616372
Trimble ME et al. Fatty acid transport and metabolism in the isolated perfused rat kidney. 1977 Oct 23-26 Curr Probl Clin Biochem pmid:616371
Sánchez-Serrano D et al. Enhancement of ouabain arrhythmias by fatty acids. 1980 J. Cardiovasc. Pharmacol. pmid:6156330
Pfadenhauer EH et al. Identification of the metabolites of erythro-9-(2-hydroxy-3-nonyl)hypoxanthine from laboratory animals. 1984 May-Jun Drug Metab. Dispos. pmid:6145553
Rofe AM and Williamson DH Metabolic effects of vasopressin infusion in the starved rat. Reversal of ketonaemia. 1983 Biochem. J. pmid:6135420
Henze K et al. The effect of hydrocortisone on cholesterol metabolism of cultured human skin fibroblasts. 1981 Biochim. Biophys. Acta pmid:6118180
Baraldi M et al. Toxins in hepatic encephalopathy: the role of the synergistic effect of ammonia, mercaptans and short chain fatty acids. 1984 Arch. Toxicol. Suppl. pmid:6097201
Sundin U et al. Thyroid-catecholamine interactions in isolated rat brown adipocytes. 1984 Metab. Clin. Exp. pmid:6092828
Martin-Sanz P et al. Long-chain fatty acids and their acyl-CoA esters cause the translocation of phosphatidate phosphohydrolase from the cytosolic to the microsomal fraction of rat liver. 1984 FEBS Lett. pmid:6090213
Katoh K and Tsuda T Effects of acetylcholine and short-chain fatty acids on acinar cells of the exocrine pancreas in sheep. 1984 J. Physiol. (Lond.) pmid:6084059
Trauner DA and Huttenlocher PR Short chain fatty acid-induced central hyperventilation in rabbits. 1978 Neurology pmid:567765
Brodersen R and Hansen P Bilirubin displacing effect of stabilizers added to injectable preparations of human serum albumin. 1977 Acta Paediatr Scand pmid:557276
McGarry JD and Foster DW The regulation of ketogenesis from octanoic acid. The role of the tricarboxylic acid cycle and fatty acid synthesis. 1971 J. Biol. Chem. pmid:5543682
Clark SB The uptake of oleic acid by rat small intestine: a comparison of methodologies. 1971 J. Lipid Res. pmid:5542704
Schröder K et al. [Energy metabolism of the rat renal cortex, as measured by incubation in various substrates]. 1979 Acta Biol. Med. Ger. pmid:543370
Skrede S and Slaattelid O Fatty acid metabolism during hypothermic perfusion of the isolated dog kidney. 1979 Scand. J. Clin. Lab. Invest. pmid:531496
Abidov AA et al. [Strophantin K action on caprylate oxidation in the myocardium]. 1971 Sep-Oct Farmakol Toksikol pmid:5151251
Bach A et al. Octanoate metabolism in the isolated perfused rat liver. II. Comparison with a long chain fatty acid. 1975 Arch. Int. Physiol. Biochim. pmid:50825
Valdivia MM et al. [Effect of octanoic acid on the insulin secretion in response to glucose in vitro (author's transl)]. 1979 Rev. Esp. Fisiol. pmid:504776
Paquet RJ et al. Effects of thiamine deficiency and octanoate administration, in vivo, on gluconeogenesis in rat kidney slices and on amino acid profile in rat liver. 1972 Proc. Soc. Exp. Biol. Med. pmid:5039394
Sallee VL et al. Determination of unidirectional uptake rates for lipids across the intestinal brush border. 1972 J. Lipid Res. pmid:5016300
Campillo JE et al. Effect of oleic and octanoic acids on glucose-induced insulin release in vitro. 1979 Diabete Metab pmid:499632
Andersen JM and Dietschy JM Absolute rates of cholesterol synthesis in extrahepatic tissues measured with 3H-labeled water and 14C-labeled substrates. 1979 J. Lipid Res. pmid:490050
Fischer JH et al. Free fatty acid and glucose metabolism during hypothermic perfusion of canine kidneys. 1979 Eur Surg Res pmid:488147
Glick MR et al. Glucose and octanoate utilization by isolated adult rat heart cells. 1974 Life Sci. pmid:4829540