octanoic acid

octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.

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Introduction

To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with octanoic acid?

octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with octanoic acid

MeSH term MeSH ID Detail
Biliary Fistula D001658 13 associated lipids
Campylobacter Infections D002169 13 associated lipids
Hypertension, Portal D006975 12 associated lipids
Amyotrophic Lateral Sclerosis D000690 11 associated lipids
Insulin Resistance D007333 99 associated lipids
Diabetic Neuropathies D003929 5 associated lipids
Critical Illness D016638 13 associated lipids
Endotoxemia D019446 27 associated lipids
Memory Disorders D008569 33 associated lipids
Cholestasis, Extrahepatic D001651 7 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with octanoic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with octanoic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with octanoic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with octanoic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with octanoic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with octanoic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with octanoic acid

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Authors Title Published Journal PubMed Link
Turcotte LP et al. High carbohydrate availability increases LCFA uptake and decreases LCFA oxidation in perfused muscle. 2002 Am. J. Physiol. Endocrinol. Metab. pmid:11739099
Iwahashi H et al. Cytochrome c catalyses the formation of pentyl radical and octanoic acid radical from linoleic acid hydroperoxide. 2002 Biochem. J. pmid:11742529
Brown AM et al. Metabolic substrates other than glucose support axon function in central white matter. 2001 J. Neurosci. Res. pmid:11746409
Gorenflo V et al. Development of a process for the biotechnological large-scale production of 4-hydroxyvalerate-containing polyesters and characterization of their physical and mechanical properties. 2001 Biomacromolecules pmid:11749154
Corbin PS et al. Biocompatible polyester macroligands: new subunits for the assembly of star-shaped polymers with luminescent and cleavable metal cores. 2001 Biomacromolecules pmid:11749177
Kimura M et al. A sensitive and simplified method to analyze free fatty acids in children with mitochondrial beta oxidation disorders using gas chromatography/mass spectrometry and dried blood spots. 2002 Clin. Chim. Acta pmid:11750281
Bluck LJ et al. Measurement of gastric emptying in man using deuterated octanoic acid. 2002 Rapid Commun. Mass Spectrom. pmid:11754258
Wyse CA et al. Use of the 13C-octanoic acid breath test for assessment of solid-phase gastric emptying in dogs. 2001 Am. J. Vet. Res. pmid:11763185
Gonlachanvit S et al. Effect of meal size and test duration on gastric emptying and gastric myoelectrical activity as determined with simultaneous [13C]octanoate breath test and electrogastrography in normal subjects using a muffin meal. 2001 Dig. Dis. Sci. pmid:11768254
Kojima M et al. Purification and distribution of ghrelin: the natural endogenous ligand for the growth hormone secretagogue receptor. 2001 Horm. Res. pmid:11786694
Leverve XM and Fontaine E Role of substrates in the regulation of mitochondrial function in situ. 2001 Sep-Nov IUBMB Life pmid:11798036
Apel CL et al. Self-assembled vesicles of monocarboxylic acids and alcohols: conditions for stability and for the encapsulation of biopolymers. 2002 Biochim. Biophys. Acta pmid:11825583
Kurvinen JP et al. Regioisomers of octanoic acid-containing structured triacylglycerols analyzed by tandem mass spectrometry using ammonia negative ion chemical ionization. 2001 Lipids pmid:11834091
Torres-Guzmán R et al. Substrate specificity of penicillin acylase from Streptomyces lavendulae. 2002 Biochem. Biophys. Res. Commun. pmid:11855830
Jones CD The genetic basis of larval resistance to a host plant toxin in Drosophila sechellia. 2001 Genet. Res. pmid:11865712
Green PR et al. Formation of short chain length/medium chain length polyhydroxyalkanoate copolymers by fatty acid beta-oxidation inhibited Ralstonia eutropha. 2002 Jan-Feb Biomacromolecules pmid:11866575
Pera P et al. Influence of mastication on gastric emptying. 2002 J. Dent. Res. pmid:11876271
McLay JC et al. Inhibition of bacterial foodborne pathogens by the lactoperoxidase system in combination with monolaurin. 2002 Int. J. Food Microbiol. pmid:11883670
Gwak HS and Chun IK Effect of vehicles and penetration enhancers on the in vitro percutaneous absorption of tenoxicam through hairless mouse skin. 2002 Int J Pharm pmid:11891070
Liggins RT and Burt HM Polyether-polyester diblock copolymers for the preparation of paclitaxel loaded polymeric micelle formulations. 2002 Adv. Drug Deliv. Rev. pmid:11897145