| MeSH term | MeSH ID | Detail |
|---|---|---|
| Biliary Fistula | D001658 | 13 associated lipids |
| Campylobacter Infections | D002169 | 13 associated lipids |
| Hypertension, Portal | D006975 | 12 associated lipids |
| Amyotrophic Lateral Sclerosis | D000690 | 11 associated lipids |
| Insulin Resistance | D007333 | 99 associated lipids |
| Diabetic Neuropathies | D003929 | 5 associated lipids |
| Critical Illness | D016638 | 13 associated lipids |
| Endotoxemia | D019446 | 27 associated lipids |
| Memory Disorders | D008569 | 33 associated lipids |
| Cholestasis, Extrahepatic | D001651 | 7 associated lipids |
octanoic acid
octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.
Cross Reference
Introduction
To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with octanoic acid?
octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with octanoic acid
PubChem Associated disorders and diseases
What pathways are associated with octanoic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with octanoic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with octanoic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with octanoic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with octanoic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with octanoic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with octanoic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Parameswaran M and Arinze IJ | Phosphoenolpyruvate synthesis by fetal guinea-pig liver mitochondria. | 1981 | Biochim. Biophys. Acta | pmid:7225415 |
| Christensen E et al. | Beta-oxidation of medium chain (C8-C14) fatty acids studied in isolated liver cells. | 1989 | Biochim. Biophys. Acta | pmid:2752017 |
| Mannaerts GP et al. | Hepatic fatty acid oxidation and ketogenesis after clofibrate treatment. | 1978 | Biochim. Biophys. Acta | pmid:656451 |
| Nieuwenhuizen W et al. | Purification and properties of two lipases from pig adipose tissue. | 1976 | Biochim. Biophys. Acta | pmid:7300 |
| MartÃnez Izquierdo JA et al. | Fatty acid-glucose interaction in the control of protein synthesis by isolated rat lung cells. | 1983 | Biochim. Biophys. Acta | pmid:6615881 |
| GLENN JL et al. | Rare-earth fatty liver. I. Octanoate oxidation and energy production. | 1962 | Biochim. Biophys. Acta | pmid:13899206 |
| DIANZANI MU and MARINARI U | The octanoate oxidation by mitochondria from faty livers. | 1961 | Biochim. Biophys. Acta | pmid:13722612 |
| Kohlwein SD and Paltauf F | Uptake of fatty acids by the yeasts, Saccharomyces uvarum and Saccharomycopsis lipolytica. | 1984 | Biochim. Biophys. Acta | pmid:6696936 |
| McDonough KH et al. | Effects of oxygen radicals on substrate oxidation by cardiac myocytes. | 1987 | Biochim. Biophys. Acta | pmid:2822138 |
| Groot PH and Hülsmann WC | The activation and oxidation of octanoate and palmitate by rat skeletal muscle mitochondria. | 1973 | Biochim. Biophys. Acta | pmid:4741907 |
| Barron JT et al. | Oxidation of acetate and octanoate and its relation to glucose metabolism in contracting porcine carotid artery. | 1997 | Biochim. Biophys. Acta | pmid:9452767 |
| Cheng Y and Hauton D | Cold acclimation induces physiological cardiac hypertrophy and increases assimilation of triacylglycerol metabolism through lipoprotein lipase. | 2008 | Biochim. Biophys. Acta | pmid:18722549 |
| Jakobs BS et al. | Beta-oxidation of fatty acids in cultured human skin fibroblasts devoid of the capacity for oxidative phosphorylation. | 1994 | Biochim. Biophys. Acta | pmid:8123680 |
| Decagny B et al. | 1H-NMR on line monitoring of water activity during lipase catalysed esterification. | 1998 | Biochim. Biophys. Acta | pmid:9748540 |
| Yon JO et al. | Incorporation of extracellular phospholipids and their effect on the growth and lipid metabolism of the Saccharomyces cerevisiae cho1/pss mutant. | 1998 | Biochim. Biophys. Acta | pmid:9767089 |
| Kato T et al. | Short- and medium-chain fatty acids enhance the cell surface expression and transport capacity of the bile salt export pump (BSEP/ABCB11). | 2010 | Biochim. Biophys. Acta | pmid:20398791 |
| Noy N and Zakim D | Substrate specificity of fatty-acyl-CoA ligase in liver microsomes. | 1985 | Biochim. Biophys. Acta | pmid:3970953 |
| Wanders RJ and Ijlst L | Fatty acid beta-oxidation in leukocytes from control subjects and medium-chain acyl-CoA dehydrogenase deficient patients. | 1992 | Biochim. Biophys. Acta | pmid:1737072 |
| Matsuki H et al. | Specific and non-specific binding of long-chain fatty acids to firefly luciferase: cutoff at octanoate. | 1999 | Biochim. Biophys. Acta | pmid:9878713 |
| Stace PB et al. | Cyclic AMP and free fatty acids in the longer-term regulation of pyruvate dehydrogenase kinase in rat soleus muscle. | 1992 | Biochim. Biophys. Acta | pmid:1319745 |
| Hinson JA and Neal RA | An examination of octanol and octanal metabolism to octanoic acid by horse liver alcohol dehydrogenase. | 1975 | Biochim. Biophys. Acta | pmid:165828 |
| Apel CL et al. | Self-assembled vesicles of monocarboxylic acids and alcohols: conditions for stability and for the encapsulation of biopolymers. | 2002 | Biochim. Biophys. Acta | pmid:11825583 |
| Zabłocki K et al. | The inhibitory effect of octanoate, palmitate and oleate on glucose formation in rabbit kidney tubules. | 1983 | Biochim. Biophys. Acta | pmid:6838901 |
| Evtodienko VY et al. | Effect of the alkyl chain length of monocarboxylic acid on the permeation through bilayer lipid membranes. | 1996 | Biochim. Biophys. Acta | pmid:8664324 |
| Latipää PM et al. | Regulation of fatty acid oxidation in heart muscle. Effects of pyruvate and dichloroacetate. | 1983 | Biochim. Biophys. Acta | pmid:6849964 |
| el Alaoui-Talibi Z and Moravec J | Carnitine transport and exogenous palmitate oxidation in chronically volume-overloaded rat hearts. | 1989 | Biochim. Biophys. Acta | pmid:2499353 |
| Bohnensack R and Fritz S | Stimulation of alanine metabolism by ammonia in the perfused rat liver. Quantitative analysis by means of a mathematical model. | 1991 | Biochim. Biophys. Acta | pmid:2009283 |
| Babu E et al. | Role of human organic anion transporter 4 in the transport of ochratoxin A. | 2002 | Biochim. Biophys. Acta | pmid:12063169 |
| Salesse R et al. | [Intensity and anisotropy decays measurement of perylene in pigeon erythrocyte membrane. Comparison with an isotropic viscous medium (author's transl)]. | 1981 Nov-Dec | Biochimie | pmid:7332761 |
| Pérez-Diaz J et al. | Preparation and metabolic characterization of isolated rat lung cells. | 1977 | Biochimie | pmid:195638 |
| Pochapsky SS et al. | Synthesis and tissue distribution of fluorine-18 labeled trifluorohexadecanoic acids. Considerations in the development of metabolically blocked myocardial imaging agents. | 1990 Jul-Aug | Bioconjug. Chem. | pmid:2096916 |
| van Ginkel CG et al. | Substrate specificity of a long-chain alkylamine-degrading Pseudomonas sp isolated from activated sludge. | 2008 | Biodegradation | pmid:17492358 |
| Goussen C et al. | Biological Safety of a Highly Purified 10% Liquid Intravenous Immunoglobulin Preparation from Human Plasma. | 2017 | BioDrugs | pmid:28508264 |
| Nagata J et al. | Effects of structured lipids containing eicosapentaenoic or docosahexaenoic acid and caprylic acid on serum and liver lipid profiles in rats. | 2004 | Biofactors | pmid:15630273 |
| Kundu S and Roy D | Structural study of biologically significant ligands with major birch pollen allergen Betv1 by docking and molecular dynamics simulation. | 2010 | Bioinformation | pmid:20978606 |
| Kumar S | Comparative modeling and molecular docking of orphan human CYP4V2 protein with fatty acid substrates: Insights into substrate specificity. | 2011 | Bioinformation | pmid:22355237 |
| Pahl-Wostl C and Seelig J | Ketogenesis in the living rat followed by 13C-NMR spectroscopy. Infusion of [1,3-13C]octanoate. | 1987 | Biol. Chem. Hoppe-Seyler | pmid:3593540 |
| Lemmen C et al. | Utilization of medium-chain triglycerides and octanoic acid by cultured human fibroblasts and lymphoblasts. | 1988 | Biol. Chem. Hoppe-Seyler | pmid:3242549 |
| Küster J et al. | Modulation of the sympathetic nerve action on carbohydrate and ketone body metabolism by fatty acids, glucagon und insulin in perfused rat liver. | 1989 | Biol. Chem. Hoppe-Seyler | pmid:2692615 |
| Kuge Y et al. | [1-11C]Octanoate as a PET tracer for studying ischemic stroke: evaluation in a canine model of thromboembolic stroke with positron emission tomography. | 2000 | Biol. Pharm. Bull. | pmid:10963308 |
| Tokudome Y and Otsuka M | Possibility of alveolar bone promoting enhancement by using lipophilic and/or hydrophilic zinc related compounds in zinc-deficient osteoporosis rats. | 2012 | Biol. Pharm. Bull. | pmid:22975500 |
| Uchida M and Shimizu K | 13C-acetic acid is more sensitive than 13C-octanoic acid for evaluating gastric emptying of liquid enteral nutrient formula by breath test in conscious rats. | 2007 | Biol. Pharm. Bull. | pmid:17329843 |
| Barnette D et al. | Pathogen safety profile of a 10% IgG preparation manufactured using a depth filtration-modified process. | 2012 | Biologicals | pmid:22579294 |
| Estrada R et al. | Intravenous administration of equine-derived whole IgG antivenom does not induce early adverse reactions in non-envenomed horses and cows. | 2010 | Biologicals | pmid:20833066 |
| Stucki M et al. | Investigations of prion and virus safety of a new liquid IVIG product. | 2008 | Biologicals | pmid:18337119 |
| Simsiriwong P et al. | A study on the use of caprylic acid and ammonium sulfate in combination for the fractionation of equine antivenom F(ab')(2). | 2012 | Biologicals | pmid:22704919 |
| Burnouf T et al. | Assessment of the viral safety of antivenoms fractionated from equine plasma. | 2004 | Biologicals | pmid:15536042 |
| Herrera M et al. | Development and validation of a reverse phase HPLC method for the determination of caprylic acid in formulations of therapeutic immunoglobulins and its application to antivenom production. | 2009 | Biologicals | pmid:19375941 |
| Athavale M et al. | Validation of a simple, rapid and cost effective method for the estimation of caprylic acid and sodium caprylate from biological products using NEFA-C kit. | 2010 | Biologicals | pmid:19919899 |
| Dichtelmüller H et al. | Inactivation of lipid enveloped viruses by octanoic Acid treatment of immunoglobulin solution. | 2002 | Biologicals | pmid:12127315 |