octanoic acid

octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.

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Introduction

To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with octanoic acid?

octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with octanoic acid

MeSH term MeSH ID Detail
Asthenia D001247 5 associated lipids
Intracranial Hypertension D019586 4 associated lipids
Schistosomiasis D012552 4 associated lipids
Urinary Incontinence D014549 4 associated lipids
Chest Pain D002637 4 associated lipids
Malocclusion D008310 3 associated lipids
Drug-Related Side Effects and Adverse Reactions D064420 3 associated lipids
Blind Loop Syndrome D001765 3 associated lipids
Gallstones D042882 3 associated lipids
Coccidiosis D003048 3 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with octanoic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with octanoic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with octanoic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with octanoic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with octanoic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with octanoic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with octanoic acid

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Authors Title Published Journal PubMed Link
Wang HH et al. Biosynthesis of polyhydroxyalkanoate homopolymers by Pseudomonas putida. 2011 Appl. Microbiol. Biotechnol. pmid:21046374
Zheng X et al. A novel cold-adapted lipase from Acinetobacter sp. XMZ-26: gene cloning and characterisation. 2011 Appl. Microbiol. Biotechnol. pmid:21336927
Fu Y et al. Metabolic flux analysis of Escherichia coli MG1655 under octanoic acid (C8) stress. 2015 Appl. Microbiol. Biotechnol. pmid:25620365
Demirev AV et al. The role of acyl-coenzyme A carboxylase complex in lipstatin biosynthesis of Streptomyces toxytricini. 2010 Appl. Microbiol. Biotechnol. pmid:20437235
Ren Q et al. Enatiomerically pure hydroxycarboxylic acids: current approaches and future perspectives. 2010 Appl. Microbiol. Biotechnol. pmid:20393709
Delamarre SC and Batt CA Comparative study of promoters for the production of polyhydroxyalkanoates in recombinant strains of Wautersia eutropha. 2006 Appl. Microbiol. Biotechnol. pmid:16362422
Conte E et al. Regulation of polyhydroxyalkanoate synthases (phaC1 and phaC2) gene expression in Pseudomonas corrugata. 2006 Appl. Microbiol. Biotechnol. pmid:16607528
Liu P et al. Membrane stress caused by octanoic acid in Saccharomyces cerevisiae. 2013 Appl. Microbiol. Biotechnol. pmid:23435986
Lu XY et al. Production of poly(3-hydroxybutyrate- co-3-hydroxyhexanoate) with flexible 3-hydroxyhexanoate content in Aeromonas hydrophila CGMCC 0911. 2004 Appl. Microbiol. Biotechnol. pmid:12920488
Diaz De Rienzo MA et al. Effect of biosurfactants on Pseudomonas aeruginosa and Staphylococcus aureus biofilms in a BioFlux channel. 2016 Appl. Microbiol. Biotechnol. pmid:26825819
Hoffmann N et al. Homologous functional expression of cryptic phaG from Pseudomonas oleovorans establishes the transacylase-mediated polyhydroxyalkanoate biosynthetic pathway. 2000 Appl. Microbiol. Biotechnol. pmid:11131392
Sato S et al. Expression and characterization of (R)-specific enoyl coenzyme A hydratases making a channeling route to polyhydroxyalkanoate biosynthesis in Pseudomonas putida. 2011 Appl. Microbiol. Biotechnol. pmid:21327961
Zentek J et al. Intestinal concentrations of free and encapsulated dietary medium-chain fatty acids and effects on gastric microbial ecology and bacterial metabolic products in the digestive tract of piglets. 2012 Arch Anim Nutr pmid:22397093
Morimoto K et al. Effect of medium-chain fatty acid salts on penetration of a hydrophilic compound and a macromolecular compound across rabbit corneas. 1989 Nov-Dec Arch Int Pharmacodyn Ther pmid:2484010
Gumus S et al. The role of oxidative stress and effect of alpha-lipoic acid in reexpansion pulmonary edema - an experimental study. 2010 Arch Med Sci pmid:22427756
COHEN R Four new fungicides for Coccidioides immitis: 1. Sodium caprylate. 2. Ethyl vanillate 3. Fradicin. 4. Thiolutin. 1951 Arch Pediatr pmid:14847786
COHEN R and PERSKY M Sodium caprylate treatment for thrusii. 1951 Arch Pediatr pmid:14800560
Bach A et al. Octanoate metabolism in the isolated perfused rat liver. I. Methodology and preliminary results. 1973 Arch Sci Physiol (Paris) pmid:4780669
Zaleski J and Bryla J Effects of oleate, palmitate, and octanoate on gluconeogenesis in isolated rabbit liver cells. 1977 Arch. Biochem. Biophys. pmid:921276
Becker CM and Harris RA Influence of valproic acid on hepatic carbohydrate and lipid metabolism. 1983 Arch. Biochem. Biophys. pmid:6407400