octanoic acid

octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.

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Introduction

To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with octanoic acid?

octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with octanoic acid

MeSH term MeSH ID Detail
Diabetes Mellitus, Experimental D003921 85 associated lipids
Seizures D012640 87 associated lipids
Brain Ischemia D002545 89 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Insulin Resistance D007333 99 associated lipids
Glioma D005910 112 associated lipids
Inflammation D007249 119 associated lipids
Hemolysis D006461 131 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with octanoic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with octanoic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with octanoic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with octanoic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with octanoic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with octanoic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with octanoic acid

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Authors Title Published Journal PubMed Link
Darling RA et al. Mercaptoacetate and fatty acids exert direct and antagonistic effects on nodose neurons via GPR40 fatty acid receptors. 2014 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:24760994
Ke L et al. Systemic and renal haemodynamic effects of fluid bolus therapy: sodium chloride versus sodium octanoate-balanced solution. 2014 Crit Care Resusc pmid:24588433
Morais V et al. Immunoglobulin purification by caprylic acid. 2014 Methods Mol. Biol. pmid:24648074
Zurich MG et al. Evaluation of aggregating brain cell cultures for the detection of acute organ-specific toxicity. 2013 Toxicol In Vitro pmid:22954530
Auriol S et al. Safety of medium-chain triglycerides used as an intraocular tamponading agent in an experimental vitrectomy model rabbit. 2013 Retina (Philadelphia, Pa.) pmid:22902566
Nguyen NQ et al. Gastric emptying measurement of liquid nutrients using the (13)C-octanoate breath test in critically ill patients: a comparison with scintigraphy. 2013 Intensive Care Med pmid:23471513
Bauchart-Thevret C et al. Supplementing monosodium glutamate to partial enteral nutrition slows gastric emptying in preterm pigs(1-3). 2013 J. Nutr. pmid:23446960
Baskaran SA et al. Inactivation of Escherichia coli O157:H7 on cattle hides by caprylic acid and β-resorcylic acid. 2013 J. Food Prot. pmid:23433381
Haubenberger D et al. Octanoic acid in alcohol-responsive essential tremor: a randomized controlled study. 2013 Neurology pmid:23408867
Tong HF et al. Caprylate as the albumin-selective modifier to improve IgG purification with hydrophobic charge-induction chromatography. 2013 J Chromatogr A pmid:23473512
Bruno G et al. 13C-octanoic acid breath test to study gastric emptying time. 2013 Eur Rev Med Pharmacol Sci pmid:24443070
Librán-Pérez M et al. Response of hepatic lipid and glucose metabolism to a mixture or single fatty acids: Possible presence of fatty acid-sensing mechanisms. 2013 Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. pmid:23010243
Librán-Pérez M et al. Oleic acid and octanoic acid sensing capacity in rainbow trout Oncorhynchus mykiss is direct in hypothalamus and Brockmann bodies. 2013 PLoS ONE pmid:23533628
Librán-Pérez M et al. In vitro response of putative fatty acid-sensing systems in rainbow trout liver to increased levels of oleate or octanoate. 2013 Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. pmid:23542747
Creedon CT et al. Assessment of gastric emptying in non-obese diabetic mice using a [13C]-octanoic acid breath test. 2013 J Vis Exp pmid:23542813
Alva-Murillo N et al. Effects of sodium octanoate on innate immune response of mammary epithelial cells during Staphylococcus aureus internalization. 2013 Biomed Res Int pmid:23509807
Yang Y and McClements DJ Vitamin E and vitamin E acetate solubilization in mixed micelles: physicochemical basis of bioaccessibility. 2013 J Colloid Interface Sci pmid:23768725
Corona-Castañeda B et al. Modulators of antibiotic activity from Ipomoea murucoides. 2013 Phytochemistry pmid:23920226
de Oliveira AL et al. Adrenergic metabolic and hemodynamic effects of octopamine in the liver. 2013 Int J Mol Sci pmid:24196353
Choi MJ et al. New decontamination method based on caprylic acid in combination with citric acid or vanillin for eliminating Cronobacter sakazakii and Salmonella enterica serovar Typhimurium in reconstituted infant formula. 2013 Int. J. Food Microbiol. pmid:24042002