octanoic acid

octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.

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Introduction

To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with octanoic acid?

octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with octanoic acid

MeSH term MeSH ID Detail
Esophageal Motility Disorders D015154 1 associated lipids
Critical Illness D016638 13 associated lipids
Liver Failure D017093 5 associated lipids
Prion Diseases D017096 2 associated lipids
Skin Diseases, Bacterial D017192 8 associated lipids
Gastroparesis D018589 2 associated lipids
Endotoxemia D019446 27 associated lipids
Intracranial Hypertension D019586 4 associated lipids
REM Sleep Behavior Disorder D020187 1 associated lipids
Essential Tremor D020329 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with octanoic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with octanoic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with octanoic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with octanoic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with octanoic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with octanoic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with octanoic acid

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Authors Title Published Journal PubMed Link
Wang HH et al. Biosynthesis of polyhydroxyalkanoate homopolymers by Pseudomonas putida. 2011 Appl. Microbiol. Biotechnol. pmid:21046374
Fu Y et al. Metabolic flux analysis of Escherichia coli MG1655 under octanoic acid (C8) stress. 2015 Appl. Microbiol. Biotechnol. pmid:25620365
Demirev AV et al. The role of acyl-coenzyme A carboxylase complex in lipstatin biosynthesis of Streptomyces toxytricini. 2010 Appl. Microbiol. Biotechnol. pmid:20437235
Ren Q et al. Enatiomerically pure hydroxycarboxylic acids: current approaches and future perspectives. 2010 Appl. Microbiol. Biotechnol. pmid:20393709
Niewerth H et al. Synthesis and biotransformation of 2-alkyl-4(1H)-quinolones by recombinant Pseudomonas putida KT2440. 2011 Appl. Microbiol. Biotechnol. pmid:21670979
Conte E et al. Regulation of polyhydroxyalkanoate synthases (phaC1 and phaC2) gene expression in Pseudomonas corrugata. 2006 Appl. Microbiol. Biotechnol. pmid:16607528
Liu P et al. Membrane stress caused by octanoic acid in Saccharomyces cerevisiae. 2013 Appl. Microbiol. Biotechnol. pmid:23435986
Lu XY et al. Production of poly(3-hydroxybutyrate- co-3-hydroxyhexanoate) with flexible 3-hydroxyhexanoate content in Aeromonas hydrophila CGMCC 0911. 2004 Appl. Microbiol. Biotechnol. pmid:12920488
Diaz De Rienzo MA et al. Effect of biosurfactants on Pseudomonas aeruginosa and Staphylococcus aureus biofilms in a BioFlux channel. 2016 Appl. Microbiol. Biotechnol. pmid:26825819
Hoffmann N et al. Homologous functional expression of cryptic phaG from Pseudomonas oleovorans establishes the transacylase-mediated polyhydroxyalkanoate biosynthetic pathway. 2000 Appl. Microbiol. Biotechnol. pmid:11131392
Sato S et al. Expression and characterization of (R)-specific enoyl coenzyme A hydratases making a channeling route to polyhydroxyalkanoate biosynthesis in Pseudomonas putida. 2011 Appl. Microbiol. Biotechnol. pmid:21327961
Durner R et al. Accumulation of Poly[(R)-3-hydroxyalkanoates] in Pseudomonas oleovorans during growth with octanoate in continuous culture at different dilution rates. 2000 Appl. Environ. Microbiol. pmid:10919799
Hajjaj H et al. Medium-chain fatty acids affect citrinin production in the filamentous fungus Monascus ruber. 2000 Appl. Environ. Microbiol. pmid:10698780
Van Immerseel F et al. Medium-chain fatty acids decrease colonization and invasion through hilA suppression shortly after infection of chickens with Salmonella enterica serovar Enteritidis. 2004 Appl. Environ. Microbiol. pmid:15184160
Viegas CA et al. The H(+)-ATPase in the plasma membrane of Saccharomyces cerevisiae is activated during growth latency in octanoic acid-supplemented medium accompanying the decrease in intracellular pH and cell viability. 1998 Appl. Environ. Microbiol. pmid:9464423
Solis de los Santos F et al. Therapeutic supplementation of caprylic acid in feed reduces Campylobacter jejuni colonization in broiler chicks. 2008 Appl. Environ. Microbiol. pmid:18502935
Lindenkamp N et al. Genetically modified strains of Ralstonia eutropha H16 with β-ketothiolase gene deletions for production of copolyesters with defined 3-hydroxyvaleric acid contents. 2012 Appl. Environ. Microbiol. pmid:22636005
Elbahloul Y and Steinbüchel A Large-scale production of poly(3-hydroxyoctanoic acid) by Pseudomonas putida GPo1 and a simplified downstream process. 2009 Appl. Environ. Microbiol. pmid:19047387
Ramsay BA et al. Effect of nitrogen limitation on long-side-chain poly-beta-hydroxyalkanoate synthesis by Pseudomonas resinovorans. 1992 Appl. Environ. Microbiol. pmid:1610198
Zhang K et al. Regulation of the Docosapentaenoic Acid/Docosahexaenoic Acid Ratio (DPA/DHA Ratio) in Schizochytrium limacinum B4D1. 2017 Appl. Biochem. Biotechnol. pmid:27832512