octanoic acid

octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.

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Introduction

To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with octanoic acid?

octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with octanoic acid

MeSH term MeSH ID Detail
Essential Tremor D020329 2 associated lipids
Intracranial Hypertension D019586 4 associated lipids
Hepatorenal Syndrome D006530 1 associated lipids
Flatulence D005414 1 associated lipids
Skin Diseases, Bacterial D017192 8 associated lipids
Urinary Incontinence D014549 4 associated lipids
Chest Pain D002637 4 associated lipids
Giardiasis D005873 3 associated lipids
Severe Acute Respiratory Syndrome D045169 1 associated lipids
Chronic Disease D002908 7 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with octanoic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with octanoic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with octanoic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with octanoic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with octanoic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with octanoic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with octanoic acid

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Authors Title Published Journal PubMed Link
Jakobs BS et al. Beta-oxidation of fatty acids in cultured human skin fibroblasts devoid of the capacity for oxidative phosphorylation. 1994 Biochim. Biophys. Acta pmid:8123680
Morand C et al. Importance of the modulation of glycolysis in the control of lactate metabolism by fatty acids in isolated hepatocytes from fed rats. 1994 Arch. Biochem. Biophys. pmid:8135535
Mao LF et al. Hepatic beta-oxidation of 3-phenylpropionic acid and the stereospecific dehydration of (R)- and (S)-3-hydroxy-3-phenylpropionyl-CoA by different enoyl-CoA hydratases. 1994 Biochemistry pmid:8136368
Bennett MJ et al. Population screening for medium-chain acyl-CoA dehydrogenase deficiency: analysis of medium-chain fatty acids and acylglycines in blood spots. 1994 Ann. Clin. Biochem. pmid:8154855
Zhang Y et al. Nonhomogeneous labeling of liver extra-mitochondrial acetyl-CoA. Implications for the probing of lipogenic acetyl-CoA via drug acetylation and for the production of acetate by the liver. 1994 J. Biol. Chem. pmid:8157628
Tsai CS and al-Kassim LS Multifunctional activities of pickerel liver alcohol dehydrogenase. 1993 Sep-Oct Biochem. Cell Biol. pmid:8192894
Mitkov D The role of the octanoic fatty acid in the pathogenesis of the metabolic alkalosis in experimental liver failure. 1993 Folia Med (Plovdiv) pmid:8194797
Ben Cheikh R et al. Control of oxidative metabolism in volume-overloaded rat hearts: effects of different lipid substrates. 1994 Am. J. Physiol. pmid:8203607
Morris TW et al. Identification of the gene encoding lipoate-protein ligase A of Escherichia coli. Molecular cloning and characterization of the lplA gene and gene product. 1994 J. Biol. Chem. pmid:8206909
Massolini G et al. Determination of the magnitude and enantioselectivity of ligand binding to rat and rabbit serum albumins using immobilized-protein high performance liquid chromatography stationary phases. 1993 Biochem. Pharmacol. pmid:8216380
Alvarez CV et al. Regulation of prothymosin alpha mRNA levels in rat pituitary tumor cells. 1993 Neuroendocrinology pmid:8232763
Adams SH and Odle J Plasma beta-hydroxybutyrate after octanoate challenge: attenuated ketogenic capacity in neonatal swine. 1993 Am. J. Physiol. pmid:8238444
Martín-Requero A et al. Reciprocal changes in gluconeogenesis and ureagenesis induced by fatty acid oxidation. 1993 Metab. Clin. Exp. pmid:8246772
Guimbretiere J et al. [A further case of albumin auto-agglutination in a blood donor]. 1976 Rev. Fr. Transfus. Immunohematol. pmid:824703
Dieuaide M et al. Effects of glucose starvation on the oxidation of fatty acids by maize root tip mitochondria and peroxisomes: evidence for mitochondrial fatty acid beta-oxidation and acyl-CoA dehydrogenase activity in a higher plant. 1993 Biochem. J. pmid:8250843
Odle J et al. Emulsification and fatty acid chain length affect the kinetics of [14C]-medium-chain triacylglycerol utilization by neonatal piglets. 1994 J. Nutr. pmid:8283298
Viegas CA et al. Regulation of the expression of the H(+)-ATPase genes PMA1 and PMA2 during growth and effects of octanoic acid in Saccharomyces cerevisiae. 1994 Biochim. Biophys. Acta pmid:8286419
Fitzsimmons ME and Anders MW Fatty acid beta-oxidation-dependent bioactivation of halogenated thiaalkanoic acids in isolated rat hepatocytes. 1993 Sep-Oct Chem. Res. Toxicol. pmid:8292744
Hulsmann WC et al. Imminent ischemia in normal and hypertrophic Langendorff rat hearts; effects of fatty acids and superoxide dismutase monitored by NADH surface fluorescence. 1993 Biochim. Biophys. Acta pmid:8318552
Wieland TM et al. Utilization of medium-chain triglycerides by neonatal pigs: effects of emulsification and dose delivered. 1993 J. Anim. Sci. pmid:8349513