MeSH term | MeSH ID | Detail |
---|---|---|
Edema | D004487 | 152 associated lipids |
Colonic Neoplasms | D003110 | 161 associated lipids |
Body Weight | D001835 | 333 associated lipids |
octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.
To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with octanoic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Miller TB | Cardiac performance of isolated perfused hearts from alloxan diabetic rats. | 1979 | Am. J. Physiol. | pmid:443443 |
Hollander D | Retinol lymphatic and portal transport: influence of pH, bile, and fatty acids. | 1980 | Am. J. Physiol. | pmid:7435575 |
Barbee RW et al. | T3 treatment does not prevent myocardial dysfunction in chronically diabetic rats. | 1988 | Am. J. Physiol. | pmid:2830793 |
Patel TB | Effect of sulfonylureas on hepatic fatty acid oxidation. | 1986 | Am. J. Physiol. | pmid:3090894 |
Lemieux G et al. | Glutamine synthetase and glutamyltransferase in the kidney of man, dog, and rat. | 1976 | Am. J. Physiol. | pmid:10736 |
REES ED and KLINE DL | Metabolism of octanoate by fatty liver slices. | 1957 | Am. J. Physiol. | pmid:13470069 |
Matsumura T et al. | O2 uptake in periportal and pericentral regions of liver lobule in perfused liver. | 1986 | Am. J. Physiol. | pmid:3717341 |
Maes BD et al. | Gastric emptying flow curves separated from carbon-labeled octanoic acid breath test results. | 1998 | Am. J. Physiol. | pmid:9655697 |
Sidossis LS et al. | Regulation of fatty acid oxidation in untrained vs. trained men during exercise. | 1998 | Am. J. Physiol. | pmid:9530135 |
Chen TM et al. | Effects of insulin on glucose uptake by rat hearts during and after coronary flow reduction. | 1997 | Am. J. Physiol. | pmid:9374750 |
Adams SH and Odle J | Plasma beta-hydroxybutyrate after octanoate challenge: attenuated ketogenic capacity in neonatal swine. | 1993 | Am. J. Physiol. | pmid:8238444 |
Beaufrere B et al. | Apparent decreased oxidation and turnover of leucine during infusion of medium-chain triglycerides. | 1985 | Am. J. Physiol. | pmid:3895976 |
Barron JT et al. | Substrate-dependent alteration in O2 consumption and energy metabolism in vascular smooth muscle. | 1996 | Am. J. Physiol. | pmid:8764234 |
Bonen A et al. | Palmitate transport and fatty acid transporters in red and white muscles. | 1998 | Am. J. Physiol. | pmid:9725814 |
Morand C et al. | Fatty acids are potent modulators of lactate utilization in isolated hepatocytes from fed rats. | 1993 | Am. J. Physiol. | pmid:8498503 |
Werner JC et al. | Fatty acid and glucose utilization in isolated, working newborn pig hearts. | 1983 | Am. J. Physiol. | pmid:6849379 |
Trimble ME | Transport and metabolism of octanoate by the perfused rat kidney. | 1979 | Am. J. Physiol. | pmid:474762 |
Lemieux G et al. | Effect of fluoroacetate on the inhibitory action of ketone bodies and fatty acids on renal ammoniagenesis. | 1979 | Am. J. Physiol. | pmid:464062 |
Odessey R and Chace KV | Utilization of endogenous lipid, glycogen, and protein by rabbit aorta. | 1982 | Am. J. Physiol. | pmid:7091374 |
Tanner GA et al. | Excretion of phenol red by the Necturus kidney. | 1979 | Am. J. Physiol. | pmid:443381 |