MeSH term | MeSH ID | Detail |
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Flatulence | D005414 | 1 associated lipids |
Dumping Syndrome | D004377 | 1 associated lipids |
Snake Bites | D012909 | 1 associated lipids |
octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.
To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with octanoic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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McLaren RD et al. | The use of caprylic acid for the extraction of the immunoglobulin fraction from egg yolk of chickens immunised with ovine alpha-lactalbumin. | 1994 | J. Immunol. Methods | pmid:7822824 |
Carnielli VP et al. | Conversion of octanoic acid into long-chain saturated fatty acids in premature infants fed a formula containing medium-chain triglycerides. | 1994 | Metab. Clin. Exp. | pmid:7934982 |
Bhanushali JK et al. | Simple method to purify chicken immunoglobulin G. | 1994 | Poult. Sci. | pmid:7937478 |
Even PC et al. | Defective regulation of energy metabolism in mdx-mouse skeletal muscles. | 1994 | Biochem. J. | pmid:7999003 |
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Rojas G et al. | Caprylic acid fractionation of hyperimmune horse plasma: description of a simple procedure for antivenom production. | 1994 | Toxicon | pmid:8016856 |
Gavva SR et al. | A 13C isotopomer n.m.r. method for monitoring incomplete beta-oxidation of fatty acids in intact tissue. | 1994 | Biochem. J. | pmid:7980454 |
Zhou YP and Grill VE | Long-term exposure of rat pancreatic islets to fatty acids inhibits glucose-induced insulin secretion and biosynthesis through a glucose fatty acid cycle. | 1994 | J. Clin. Invest. | pmid:8113418 |
Jakobs BS et al. | Beta-oxidation of fatty acids in cultured human skin fibroblasts devoid of the capacity for oxidative phosphorylation. | 1994 | Biochim. Biophys. Acta | pmid:8123680 |
Mao LF et al. | Hepatic beta-oxidation of 3-phenylpropionic acid and the stereospecific dehydration of (R)- and (S)-3-hydroxy-3-phenylpropionyl-CoA by different enoyl-CoA hydratases. | 1994 | Biochemistry | pmid:8136368 |
Yanai S et al. | Antitumor effect of arterial administration of a medium-chain triglyceride solution of an angiogenesis inhibitor, TNP-470, in rabbits bearing VX-2 carcinoma. | 1995 | Pharm. Res. | pmid:7479548 |
Sarel I and Widmaier EP | Stimulation of steroidogenesis in cultured rat adrenocortical cells by unsaturated fatty acids. | 1995 | Am. J. Physiol. | pmid:7611525 |
Sibille B et al. | Octanoate affects 2,4-dinitrophenol uncoupling in intact isolated rat hepatocytes. | 1995 | Eur. J. Biochem. | pmid:7635161 |
Nagatsugi F et al. | 18F-labeled octanoates as potential agents for cerebral fatty acid studies. The influence of 4-substitution and the fluorine position on biodistribution. | 1995 | Chem. Pharm. Bull. | pmid:7600614 |
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Grekin RJ et al. | Pressor effects of portal venous oleate infusion. A proposed mechanism for obesity hypertension. | 1995 | Hypertension | pmid:7607723 |
Morris TW et al. | Lipoic acid metabolism in Escherichia coli: the lplA and lipB genes define redundant pathways for ligation of lipoyl groups to apoprotein. | 1995 | J. Bacteriol. | pmid:8002607 |
Redondo O et al. | Comparative kinetic study of lipases A and B from Candida rugosa in the hydrolysis of lipid p-nitrophenyl esters in mixed micelles with Triton X-100. | 1995 | Biochim. Biophys. Acta | pmid:7827103 |
Maes BD et al. | Influence of octreotide on the gastric emptying of solids and liquids in normal healthy subjects. | 1995 | Aliment. Pharmacol. Ther. | pmid:7766738 |
Martinelle M and Hult K | Kinetics of acyl transfer reactions in organic media catalysed by Candida antarctica lipase B. | 1995 | Biochim. Biophys. Acta | pmid:7669809 |
Svendsen L et al. | Development and comparison of purification strategies for chicken antibodies from egg yolk. | 1995 | Lab. Anim. Sci. | pmid:7752622 |
Pfaffenbach B et al. | [Non-invasive 13C octanoic acid breath test for measuring stomach emptying of a solid test meal--correlation with scintigraphy in diabetic patients and reproducibility in healthy probands]. | 1995 | Z Gastroenterol | pmid:7754644 |
Fryer LG et al. | The long-term regulation of skeletal muscle pyruvate dehydrogenase kinase by dietary lipid is dependent on fatty acid composition. | 1995 | Eur. J. Biochem. | pmid:7758471 |
Godet MC et al. | Inclusion/exclusion of fatty acids in amylose complexes as a function of the fatty acid chain length. | 1995 | Int. J. Biol. Macromol. | pmid:8789347 |
Tomita GM et al. | Antigenic crossreactivity and lipopolysaccharide neutralization properties of bovine immunoglobulin G. | 1995 | J. Dairy Sci. | pmid:8675757 |
Kuge Y et al. | Brain uptake and metabolism of [1-11C]octanoate in rats: pharmacokinetic basis for its application as a radiopharmaceutical for studying brain fatty acid metabolism. | 1995 | Ann Nucl Med | pmid:8534586 |
Lamas JA et al. | Caprylic acid, a medium chain saturated fatty acid, inhibits the sodium inward current in neuroglioma (NG108-15) cells. | 1995 | Neurosci. Lett. | pmid:8552316 |
Büllesbach EE and Schwabe C | Structural contribution of the A-chain loop in relaxin. | 1995 Sep-Oct | Int. J. Pept. Protein Res. | pmid:8537177 |
Yang H et al. | Enhancing the stereoselectivity and activity of Candida species lipase in organic solvent by noncovalent enzyme modification. | 1996 | Ann. N. Y. Acad. Sci. | pmid:8958099 |
Castel MA et al. | The antibodies causing thyroid stimulating hormone-binding inhibition (TSH-BI) are not responsible for the specific inhibition of gonadal steroidogenesis by Graves' sera. | 1996 | J. Reprod. Immunol. | pmid:8920164 |
Katoh K et al. | Octanoate increases cytosolic Ca2+ concentration and membrane conductance in ovine pancreatic acinar cells. | 1996 | J. Comp. Physiol. B, Biochem. Syst. Environ. Physiol. | pmid:8923746 |
Guthy E | Enteric-coated fish oil in Crohn's disease. | 1996 | N. Engl. J. Med. | pmid:8927072 |
Bojes HK and Thurman RG | Potent peroxisome proliferators inhibit beta-oxidation in the isolated perfused rat liver. | 1996 | Toxicol. Appl. Pharmacol. | pmid:8887448 |
Sidossis LS et al. | Glucose plus insulin regulate fat oxidation by controlling the rate of fatty acid entry into the mitochondria. | 1996 | J. Clin. Invest. | pmid:8941640 |
Veereman-Wauters G et al. | The 13C-octanoic acid breath test: a noninvasive technique to assess gastric emptying in preterm infants. | 1996 | J. Pediatr. Gastroenterol. Nutr. | pmid:8856575 |
Fulgencio JP et al. | Troglitazone inhibits fatty acid oxidation and esterification, and gluconeogenesis in isolated hepatocytes from starved rats. | 1996 | Diabetes | pmid:8866561 |
Amin D et al. | 1-Hydroxy-3-(methylpentylamino)-propylidene-1,1-bisphosphonic acid as a potent inhibitor of squalene synthase. | 1996 | Arzneimittelforschung | pmid:9125274 |
Constantinides PP et al. | Water-in-oil microemulsions containing medium-chain fatty acids/salts: formulation and intestinal absorption enhancement evaluation. | 1996 | Pharm. Res. | pmid:8932438 |
Kuge Y et al. | [1-11C]octanoate as a potential PET tracer for studying glial functions: PET evaluation in rats and cats. | 1996 | Nucl. Med. Biol. | pmid:9004290 |
Yamazaki S et al. | Uptake of radioactive octanoate in astrocytoma cells: basic studies for application of [11C]octanoate as a PET tracer. | 1996 | Ann Nucl Med | pmid:9006724 |
Murphy MG et al. | Abnormalities in hepatic fatty-acid metabolism in a surfactant/influenza B virus mouse model for acute encephalopathy. | 1996 | Biochim. Biophys. Acta | pmid:8611661 |
Perri F et al. | Gastric emptying and Helicobacter pylori infection in duodenal ulcer disease. | 1996 | Dig. Dis. Sci. | pmid:8617116 |
Lin X et al. | Acetate represents a major product of heptanoate and octanoate beta-oxidation in hepatocytes isolated from neonatal piglets. | 1996 | Biochem. J. | pmid:8761477 |
Barron JT et al. | Substrate-dependent alteration in O2 consumption and energy metabolism in vascular smooth muscle. | 1996 | Am. J. Physiol. | pmid:8764234 |
Petschow BW et al. | Susceptibility of Helicobacter pylori to bactericidal properties of medium-chain monoglycerides and free fatty acids. | 1996 | Antimicrob. Agents Chemother. | pmid:8834870 |
Priestman DA et al. | Pyruvate inhibition of pyruvate dehydrogenase kinase. Effects of progressive starvation and hyperthyroidism in vivo, and of dibutyryl cyclic AMP and fatty acids in cultured cardiac myocytes. | 1996 | FEBS Lett. | pmid:8814284 |
Evtodienko VY et al. | Effect of the alkyl chain length of monocarboxylic acid on the permeation through bilayer lipid membranes. | 1996 | Biochim. Biophys. Acta | pmid:8664324 |