MeSH term | MeSH ID | Detail |
---|---|---|
Gallstones | D042882 | 3 associated lipids |
Severe Acute Respiratory Syndrome | D045169 | 1 associated lipids |
Drug-Related Side Effects and Adverse Reactions | D064420 | 3 associated lipids |
octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.
To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with octanoic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Roeder LM et al. | The effects of ketone bodies, bicarbonate, and calcium on hepatic mitochondrial ketogenesis. | 1982 | Arch. Biochem. Biophys. | pmid:7138017 |
González-Manchón C et al. | Control of hepatic gluconeogenesis: role of fatty acid oxidation. | 1989 | Arch. Biochem. Biophys. | pmid:2712567 |
Morand C et al. | Importance of the modulation of glycolysis in the control of lactate metabolism by fatty acids in isolated hepatocytes from fed rats. | 1994 | Arch. Biochem. Biophys. | pmid:8135535 |
BROWN GW et al. | On the unequal conversion of the carboxyl and seventh carbons of octanoate to CO2 by liver slices. | 1954 | Arch. Biochem. Biophys. | pmid:13159319 |
Almås I et al. | The action of vasopressin and calcium on palmitate metabolism in hepatocytes and isolated mitochondria from rat liver. | 1983 | Arch. Biochem. Biophys. | pmid:6847192 |
Hu H et al. | Ethanol and oleate inhibition of alpha-ketoisovalerate and 3-hydroxyisobutyrate metabolism by isolated hepatocytes. | 1992 | Arch. Biochem. Biophys. | pmid:1444452 |
Nagi MN et al. | Biochemical properties of short- and long-chain rat liver microsomal trans-2-enoyl coenzyme A reductase. | 1983 | Arch. Biochem. Biophys. | pmid:6416174 |
Jagielski AK et al. | Purinergic regulation of glucose and glutamine synthesis in isolated rabbit kidney-cortex tubules. | 2002 | Arch. Biochem. Biophys. | pmid:12147256 |
Cessna AJ and Grover R | Exposure of ground-rig applicators to the herbicide bromoxynil applied as a 1:1 mixture of butyrate and octanoate. | 2002 | Arch. Environ. Contam. Toxicol. | pmid:11910467 |
Buchowicz I et al. | Anti-pseudomonas immunoglobulin. II. Preparation of purified sheep immunoglobulins. | 1981 | Arch. Immunol. Ther. Exp. (Warsz.) | pmid:6812541 |
Sheikh MI et al. | On the mechanism of p-piperidyl and p-benzyl sulfamyl benzoic acids transport by renal tissue. | 1978 | Arch. Int. Physiol. Biochim. | pmid:87158 |
Bach A et al. | Octanoate metabolism in the isolated perfused rat liver. II. Comparison with a long chain fatty acid. | 1975 | Arch. Int. Physiol. Biochim. | pmid:50825 |
Wei P et al. | Characterization of two soil metagenome-derived lipases with high specificity for p-nitrophenyl palmitate. | 2009 | Arch. Microbiol. | pmid:19043691 |
Morgan-Kiss RM and Cronan JE | The Lactococcus lactis FabF fatty acid synthetic enzyme can functionally replace both the FabB and FabF proteins of Escherichia coli and the FabH protein of Lactococcus lactis. | 2008 | Arch. Microbiol. | pmid:18523755 |
Sujatha K et al. | Molecular characterization of Pseudomonas sp. LDC-5 involved in accumulation of poly 3-hydroxybutyrate and medium-chain-length poly 3-hydroxyalkanoates. | 2007 | Arch. Microbiol. | pmid:17653530 |
Cabral MG et al. | Mechanisms underlying the acquisition of resistance to octanoic-acid-induced-death following exposure of Saccharomyces cerevisiae to mild stress imposed by octanoic acid or ethanol. | 2001 | Arch. Microbiol. | pmid:11382226 |
Huang CB et al. | Short- and medium-chain fatty acids exhibit antimicrobial activity for oral microorganisms. | 2011 | Arch. Oral Biol. | pmid:21333271 |
Gwak HS et al. | Effect of vehicles and enhancers on the in vitro permeation of melatonin through hairless mouse skin. | 2002 | Arch. Pharm. Res. | pmid:12135116 |
Kim HW et al. | The effect of vehicles and pressure sensitive adhesives on the percutaneous absorption of quercetin through the hairless mouse skin. | 2004 | Arch. Pharm. Res. | pmid:15357005 |
Cho CW et al. | Enhanced transdermal absorption and pharmacokinetic evaluation of pranoprofen-ethylene-vinyl acetate matrix containing penetration enhancer in rats. | 2009 | Arch. Pharm. Res. | pmid:19471890 |