MeSH term | MeSH ID | Detail |
---|---|---|
Cholestasis, Extrahepatic | D001651 | 7 associated lipids |
Asthenia | D001247 | 5 associated lipids |
Amyotrophic Lateral Sclerosis | D000690 | 11 associated lipids |
octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.
To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with octanoic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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McNamara BC and Jefcoate CR | Heterogeneous pools of cholesterol side-chain cleavage activity in adrenal mitochondria from ACTH-treated rats: differential responses to different reducing precursors. | 1990 | Mol. Cell. Endocrinol. | pmid:2176627 |
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Kim CS et al. | L-Carnitine prevents mitochondrial damage induced by octanoic acid in the rat choroid plexus. | 1990 | Brain Res. | pmid:1964833 |
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Favre-Bulle O et al. | Bioconversion of n-octane to octanoic acid by a recombinant Escherichia coli cultured in a two-liquid phase bioreactor. | 1991 | Biotechnology (N.Y.) | pmid:1367010 |
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Viegas CA and Sá-Correia I | Activation of plasma membrane ATPase of Saccharomyces cerevisiae by octanoic acid. | 1991 | J. Gen. Microbiol. | pmid:1827836 |
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Kragh-Hansen U | Octanoate binding to the indole- and benzodiazepine-binding region of human serum albumin. | 1991 | Biochem. J. | pmid:1996962 |
Dombrowski GJ and Swiatek KR | Lactate genesis by rat liver and muscle during development. | 1991 | Pediatr. Res. | pmid:1956716 |
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Bjorge SM and Baillie TA | Studies on the beta-oxidation of valproic acid in rat liver mitochondrial preparations. | 1991 Jul-Aug | Drug Metab. Dispos. | pmid:1680661 |
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Wanders RJ and Ijlst L | Fatty acid beta-oxidation in leukocytes from control subjects and medium-chain acyl-CoA dehydrogenase deficient patients. | 1992 | Biochim. Biophys. Acta | pmid:1737072 |
Kristev A et al. | Effects of the medium chain octanoic fatty acid on the contractile activity of vascular smooth muscle tissues. | 1992 | Folia Med (Plovdiv) | pmid:1364081 |
Kim CS et al. | Octanoic acid produces accumulation of monoamine acidic metabolites in the brain: interaction with organic anion transport at the choroid plexus. | 1992 | J. Neurochem. | pmid:1372345 |
Prip-Buus C et al. | Evidence for an impaired long-chain fatty acid oxidation and ketogenesis in Fao hepatoma cells. | 1992 | Eur. J. Biochem. | pmid:1356769 |
Stace PB et al. | Cyclic AMP and free fatty acids in the longer-term regulation of pyruvate dehydrogenase kinase in rat soleus muscle. | 1992 | Biochim. Biophys. Acta | pmid:1319745 |