MeSH term | MeSH ID | Detail |
---|---|---|
Drug-Related Side Effects and Adverse Reactions | D064420 | 3 associated lipids |
REM Sleep Behavior Disorder | D020187 | 1 associated lipids |
Dumping Syndrome | D004377 | 1 associated lipids |
octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.
To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with octanoic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Marquez A et al. | Optimization and validation of an automated DHS-TD-GC-MS method for the determination of aromatic esters in sweet wines. | 2014 | Talanta | pmid:24725861 |
Librán-Pérez M et al. | Central administration of oleate or octanoate activates hypothalamic fatty acid sensing and inhibits food intake in rainbow trout. | 2014 | Physiol. Behav. | pmid:24631300 |
Razmakhnin EV et al. | [The atomic emission analysis under examination of composition of gallstones]. | 2014 | Klin. Lab. Diagn. | pmid:25080794 |
Balaraman E et al. | Catalytic transformation of alcohols to carboxylic acid salts and H2 using water as the oxygen atom source. | 2013 | Nat Chem | pmid:23344447 |
Liu P et al. | Membrane stress caused by octanoic acid in Saccharomyces cerevisiae. | 2013 | Appl. Microbiol. Biotechnol. | pmid:23435986 |
Zurich MG et al. | Evaluation of aggregating brain cell cultures for the detection of acute organ-specific toxicity. | 2013 | Toxicol In Vitro | pmid:22954530 |
Oiso S et al. | Establishment of a gastric cell-based assay system for exploring inhibitors of octanoylated ghrelin production. | 2013 | J Biomol Screen | pmid:23704134 |
Auriol S et al. | Safety of medium-chain triglycerides used as an intraocular tamponading agent in an experimental vitrectomy model rabbit. | 2013 | Retina (Philadelphia, Pa.) | pmid:22902566 |
Nguyen NQ et al. | Gastric emptying measurement of liquid nutrients using the (13)C-octanoate breath test in critically ill patients: a comparison with scintigraphy. | 2013 | Intensive Care Med | pmid:23471513 |
Bauchart-Thevret C et al. | Supplementing monosodium glutamate to partial enteral nutrition slows gastric emptying in preterm pigs(1-3). | 2013 | J. Nutr. | pmid:23446960 |
Baskaran SA et al. | Inactivation of Escherichia coli O157:H7 on cattle hides by caprylic acid and β-resorcylic acid. | 2013 | J. Food Prot. | pmid:23433381 |
Haubenberger D et al. | Octanoic acid in alcohol-responsive essential tremor: a randomized controlled study. | 2013 | Neurology | pmid:23408867 |
Tong HF et al. | Caprylate as the albumin-selective modifier to improve IgG purification with hydrophobic charge-induction chromatography. | 2013 | J Chromatogr A | pmid:23473512 |
Lim CH et al. | Effect of DA-9701 on gastric emptying in a mouse model: assessment by ¹³C-octanoic acid breath test. | 2013 | World J. Gastroenterol. | pmid:23885150 |
Eder M et al. | Pharmacokinetic properties of peptidic radiopharmaceuticals: reduced uptake of (EH)3-conjugates in important organs. | 2013 | J. Nucl. Med. | pmid:23804326 |
Frauches TS et al. | Bothropic antivenom based on monoclonal antibodies, is it possible? | 2013 | Toxicon | pmid:23732123 |
Leonard PH et al. | Variability in protein quality used for embryo culture: embryotoxicity of the stabilizer octanoic acid. | 2013 | Fertil. Steril. | pmid:23602317 |
Coenen MJ et al. | Polymorphism in porphyrin monolayers: the relation between adsorption configuration and molecular conformation. | 2013 | Phys Chem Chem Phys | pmid:23620134 |
Bernardino K and de Moura AF | Aggregation thermodynamics of sodium octanoate micelles studied by means of molecular dynamics simulations. | 2013 | J Phys Chem B | pmid:23697593 |
Roda A et al. | Non-invasive panel tests for gastrointestinal motility monitoring within the MARS-500 Project. | 2013 | World J. Gastroenterol. | pmid:23599647 |
Morrill KM et al. | Estimate of serum immunoglobulin G concentration using refractometry with or without caprylic acid fractionation. | 2013 | J. Dairy Sci. | pmid:23664346 |
Fonseca CR et al. | Storage of refrigerated raw goat milk affecting the quality of whole milk powder. | 2013 | J. Dairy Sci. | pmid:23664351 |
Costello PJ et al. | Synthesis of fruity ethyl esters by acyl coenzyme A: alcohol acyltransferase and reverse esterase activities in Oenococcus oeni and Lactobacillus plantarum. | 2013 | J. Appl. Microbiol. | pmid:23216623 |
Brun AC et al. | Nissen fundoplication in children with cerebral palsy: influence on rate of gastric emptying and postprandial symptoms in relation to protein source in caloric liquid meals. | 2013 | Clin Nutr | pmid:23196118 |
Midelfort KS et al. | Redesigning and characterizing the substrate specificity and activity of Vibrio fluvialis aminotransferase for the synthesis of imagabalin. | 2013 | Protein Eng. Des. Sel. | pmid:23012440 |
Bruno G et al. | 13C-octanoic acid breath test to study gastric emptying time. | 2013 | Eur Rev Med Pharmacol Sci | pmid:24443070 |
Librán-Pérez M et al. | Response of hepatic lipid and glucose metabolism to a mixture or single fatty acids: Possible presence of fatty acid-sensing mechanisms. | 2013 | Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. | pmid:23010243 |
Librán-Pérez M et al. | Oleic acid and octanoic acid sensing capacity in rainbow trout Oncorhynchus mykiss is direct in hypothalamus and Brockmann bodies. | 2013 | PLoS ONE | pmid:23533628 |
Librán-Pérez M et al. | In vitro response of putative fatty acid-sensing systems in rainbow trout liver to increased levels of oleate or octanoate. | 2013 | Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. | pmid:23542747 |
Creedon CT et al. | Assessment of gastric emptying in non-obese diabetic mice using a [13C]-octanoic acid breath test. | 2013 | J Vis Exp | pmid:23542813 |
Alva-Murillo N et al. | Effects of sodium octanoate on innate immune response of mammary epithelial cells during Staphylococcus aureus internalization. | 2013 | Biomed Res Int | pmid:23509807 |
Yang Y and McClements DJ | Vitamin E and vitamin E acetate solubilization in mixed micelles: physicochemical basis of bioaccessibility. | 2013 | J Colloid Interface Sci | pmid:23768725 |
Corona-Castañeda B et al. | Modulators of antibiotic activity from Ipomoea murucoides. | 2013 | Phytochemistry | pmid:23920226 |
de Oliveira AL et al. | Adrenergic metabolic and hemodynamic effects of octopamine in the liver. | 2013 | Int J Mol Sci | pmid:24196353 |
Choi MJ et al. | New decontamination method based on caprylic acid in combination with citric acid or vanillin for eliminating Cronobacter sakazakii and Salmonella enterica serovar Typhimurium in reconstituted infant formula. | 2013 | Int. J. Food Microbiol. | pmid:24042002 |
Scott G et al. | Pickering stabilized peptide gel particles as tunable microenvironments for biocatalysis. | 2013 | Langmuir | pmid:24144273 |
Suzuki S et al. | Characterization of actions of octanoate on porcine preadipocytes and adipocytes differentiated in vitro. | 2013 | Biochem. Biophys. Res. Commun. | pmid:23376076 |
Hulankova R et al. | Combined antimicrobial effect of oregano essential oil and caprylic acid in minced beef. | 2013 | Meat Sci. | pmid:23743028 |
Guo H et al. | Influences of hydrocarbon linkers on the receptor binding affinities of gonadotropin-releasing hormone peptides. | 2013 | Bioorg. Med. Chem. Lett. | pmid:24018188 |
Harmancey R et al. | Decreased long-chain fatty acid oxidation impairs postischemic recovery of the insulin-resistant rat heart. | 2013 | FASEB J. | pmid:23825227 |
Shilling M et al. | Antimicrobial effects of virgin coconut oil and its medium-chain fatty acids on Clostridium difficile. | 2013 | J Med Food | pmid:24328700 |
Hungate EA et al. | A locus in Drosophila sechellia affecting tolerance of a host plant toxin. | 2013 | Genetics | pmid:24037270 |
Kursu VA et al. | Defects in mitochondrial fatty acid synthesis result in failure of multiple aspects of mitochondrial biogenesis in Saccharomyces cerevisiae. | 2013 | Mol. Microbiol. | pmid:24102902 |
Zimmermann S et al. | Screening and HPLC-Based Activity Profiling for New Antiprotozoal Leads from European Plants. | 2012 Jan-Mar | Sci Pharm | pmid:22396915 |
Morais V and Massaldi H | A model mechanism for protein precipitation by caprylic acid: application to plasma purification. | 2012 Jan-Feb | Biotechnol. Appl. Biochem. | pmid:22332745 |
Brun AC et al. | The effect of protein composition in liquid meals on gastric emptying rate in children with cerebral palsy. | 2012 | Clin Nutr | pmid:21835514 |
Hämmerle SP et al. | The single dose pharmacokinetic profile of a novel oral human parathyroid hormone formulation in healthy postmenopausal women. | 2012 | Bone | pmid:22289659 |
Fernández J et al. | Synthesis, structure and properties of poly(L-lactide-co-ε-caprolactone) statistical copolymers. | 2012 | J Mech Behav Biomed Mater | pmid:22498288 |
Lockman KA et al. | Oxidative stress rather than triglyceride accumulation is a determinant of mitochondrial dysfunction in in vitro models of hepatic cellular steatosis. | 2012 | Liver Int. | pmid:22429485 |
Cordes AA et al. | Selective domain stabilization as a strategy to reduce human serum albumin-human granulocyte colony stimulating factor aggregation rate. | 2012 | J Pharm Sci | pmid:22422106 |
Calandra P et al. | Emerging dynamics in surfactant-based liquid mixtures: octanoic acid/bis(2-ethylhexyl) amine systems. | 2012 | J Chem Phys | pmid:22360203 |
Yahashi S et al. | GHRP-6 mimics ghrelin-induced stimulation of food intake and suppression of locomotor activity in goldfish. | 2012 | Peptides | pmid:22349352 |
Tan CH et al. | Immunological properties of Hypnale hypnale (hump-nosed pit viper) venom: antibody production with diagnostic and therapeutic potentials. | 2012 | Acta Trop. | pmid:22322247 |
Ryu JK and Yoo SD | Preparation and evaluation of bicyclol microemulsions for enhanced oral bioavailability. | 2012 | Drug Dev Ind Pharm | pmid:22283588 |
Maricic MJ | Oral calcitonin. | 2012 | Curr Osteoporos Rep | pmid:22281725 |
Solano S et al. | Low pH formulation of whole IgG antivenom: impact on quality, safety, neutralizing potency and viral inactivation. | 2012 | Biologicals | pmid:22266304 |
Cordes AA et al. | Selective domain stabilization as a strategy to reduce fusion protein aggregation. | 2012 | J Pharm Sci | pmid:22234888 |
Escapa IF et al. | The polyhydroxyalkanoate metabolism controls carbon and energy spillage in Pseudomonas putida. | 2012 | Environ. Microbiol. | pmid:22225632 |
Molinas A et al. | Functional evidence of multidrug resistance transporters (MDR) in rodent olfactory epithelium. | 2012 | PLoS ONE | pmid:22563480 |
Pereira RF et al. | What drives the precipitation of long-chain calcium carboxylates (soaps) in aqueous solution? | 2012 | Phys Chem Chem Phys | pmid:22513819 |
Rucinski M et al. | Evidence suggesting that ghrelin O-acyl transferase inhibitor acts at the hypothalamus to inhibit hypothalamo-pituitary-adrenocortical axis function in the rat. | 2012 | Peptides | pmid:22543218 |
Can Güven S and Laska M | Olfactory sensitivity and odor structure-activity relationships for aliphatic carboxylic acids in CD-1 mice. | 2012 | PLoS ONE | pmid:22479594 |
Vazquez-Cruz MA et al. | Effect of maturity stage and storage on flavor compounds and sensory description of berrycactus (Myrtillocactus geometrizans). | 2012 | J. Food Sci. | pmid:22429085 |
Gschwind HP et al. | Metabolism and disposition of the oral absorption enhancer 14C-radiolabeled 8-(N-2-hydroxy-5-chlorobenzoyl)-amino-caprylic acid (5-CNAC) in healthy postmenopausal women and supplementary investigations in vitro. | 2012 | Eur J Pharm Sci | pmid:22579664 |
Simon-Colin C et al. | Biosynthesis and characterization of polyhydroxyalkanoates by Pseudomonas guezennei from alkanoates and glucose. | 2012 | Int. J. Biol. Macromol. | pmid:22947450 |
Ogungbenro K and Aarons L | A semi-mechanistic gastric emptying pharmacokinetic model for (13)C-octanoic acid: an evaluation using simulation. | 2012 | Eur J Pharm Sci | pmid:22155547 |
Otero-Patiño R et al. | Comparative study of the efficacy and safety of two polyvalent, caprylic acid fractionated [IgG and F(ab')2] antivenoms, in Bothrops asper bites in Colombia. | 2012 | Toxicon | pmid:22146491 |
Wlaź P et al. | Anticonvulsant profile of caprylic acid, a main constituent of the medium-chain triglyceride (MCT) ketogenic diet, in mice. | 2012 | Neuropharmacology | pmid:22210332 |
Morrill KM et al. | Estimate of colostral immunoglobulin G concentration using refractometry without or with caprylic acid fractionation. | 2012 | J. Dairy Sci. | pmid:22720953 |
Janssen S et al. | Sensing of fatty acids for octanoylation of ghrelin involves a gustatory G-protein. | 2012 | PLoS ONE | pmid:22768248 |
Kovalchuk NM et al. | Ionic strength and pH as control parameters for spontaneous surface oscillations. | 2012 | Langmuir | pmid:22480181 |
Hu JY et al. | Residue determination and dissipation of ioxynil octanoate in maize and soil. | 2012 | J Environ Sci Health B | pmid:22424062 |
Librán-Pérez M et al. | Evidence of a metabolic fatty acid-sensing system in the hypothalamus and Brockmann bodies of rainbow trout: implications in food intake regulation. | 2012 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:22496361 |
Zhang JH et al. | High-throughput screening of B factor saturation mutated Rhizomucor miehei lipase thermostability based on synthetic reaction. | 2012 | Enzyme Microb. Technol. | pmid:22500900 |
Nahab FB et al. | Octanoic acid suppresses harmaline-induced tremor in mouse model of essential tremor. | 2012 | Neurotherapeutics | pmid:22454323 |
Ogawa N et al. | Intestinal fatty acid infusion modulates food preference as well as calorie intake via the vagal nerve and midbrain-hypothalamic neural pathways in rats. | 2012 | Metab. Clin. Exp. | pmid:22445513 |
Tetrick MA et al. | Octanoate and nonaoate oxidation increases 50-80% over the first two days of life in piglet triceps brachii and gracilis muscle strips. | 2012 | J. Nutr. | pmid:22513984 |
Abdolmohammadi S et al. | Enhancement of mechanical and thermal properties of polycaprolactone/chitosan blend by calcium carbonate nanoparticles. | 2012 | Int J Mol Sci | pmid:22605993 |
Kube M et al. | Current view on phytoplasma genomes and encoded metabolism. | 2012 | ScientificWorldJournal | pmid:22550465 |
Wood P | Human normal immunoglobulin in the treatment of primary immunodeficiency diseases. | 2012 | Ther Clin Risk Manag | pmid:22547934 |
Li J et al. | Biodegradable thermosensitive hydrogel for SAHA and DDP delivery: therapeutic effects on oral squamous cell carcinoma xenografts. | 2012 | PLoS ONE | pmid:22529899 |
Kim JW | Could carbon breath test measurement accurately reflect gastric emptying of liquid nutrient meal in the critically ill patients? (Gut 2011;60:1336-1343). | 2012 | J Neurogastroenterol Motil | pmid:22523735 |
Delporte C | Recent advances in potential clinical application of ghrelin in obesity. | 2012 | J Obes | pmid:22523666 |
Park S et al. | Development of sandwich enzyme-linked immunosorbent assay for the detection of Cronobacter muytjensii (formerly called Enterobacter sakazakii). | 2012 | Microbiol. Immunol. | pmid:22519814 |
Liang QH et al. | Ghrelin attenuates the osteoblastic differentiation of vascular smooth muscle cells through the ERK pathway. | 2012 | PLoS ONE | pmid:22514603 |
Lin HV et al. | Butyrate and propionate protect against diet-induced obesity and regulate gut hormones via free fatty acid receptor 3-independent mechanisms. | 2012 | PLoS ONE | pmid:22506074 |
Li RL et al. | Profound hypoglycemia in starved, ghrelin-deficient mice is caused by decreased gluconeogenesis and reversed by lactate or fatty acids. | 2012 | J. Biol. Chem. | pmid:22474325 |
Nejati K and Zabihi R | Preparation and magnetic properties of nano size nickel ferrite particles using hydrothermal method. | 2012 | Chem Cent J | pmid:22462726 |
Andersen JT et al. | Structure-based mutagenesis reveals the albumin-binding site of the neonatal Fc receptor. | 2012 | Nat Commun | pmid:22215085 |
Yamada M et al. | A medium-chain fatty acid as an alternative energy source in mouse preimplantation development. | 2012 | Sci Rep | pmid:23226596 |
MaletÃnská L et al. | Characterization of new stable ghrelin analogs with prolonged orexigenic potency. | 2012 | J. Pharmacol. Exp. Ther. | pmid:22182933 |
Nóbrega AC et al. | Dyspeptic symptoms and delayed gastric emptying of solids in patients with inactive Crohn's disease. | 2012 | BMC Gastroenterol | pmid:23216812 |
Riniker S et al. | Temperature dependence of the dielectric permittivity of acetic acid, propionic acid and their methyl esters: a molecular dynamics simulation study. | 2012 | Chemphyschem | pmid:22383366 |
Takatani-Nakase T et al. | Transcutaneous immunization system using a hydrotropic formulation induces a potent antigen-specific antibody response. | 2012 | PLoS ONE | pmid:23110149 |
Faria M et al. | Surface Characterization of Asymmetric Bi-Soft Segment Poly(ester urethane urea) Membranes for Blood-Oxygenation Medical Devices. | 2012 | Int J Biomater | pmid:22164163 |
Layek B and Singh J | N-hexanoyl, N-octanoyl and N-decanoyl chitosans: Binding affinity, cell uptake, and transfection. | 2012 | Carbohydr Polym | pmid:24750737 |
Goh YS and Tan IK | Polyhydroxyalkanoate production by antarctic soil bacteria isolated from Casey Station and Signy Island. | 2012 | Microbiol. Res. | pmid:21945102 |
Chang P et al. | The antiepileptic drug valproic acid and other medium-chain fatty acids acutely reduce phosphoinositide levels independently of inositol in Dictyostelium. | 2012 | Dis Model Mech | pmid:21876211 |
Prajapati HN et al. | A comparative evaluation of mono-, di- and triglyceride of medium chain fatty acids by lipid/surfactant/water phase diagram, solubility determination and dispersion testing for application in pharmaceutical dosage form development. | 2012 | Pharm. Res. | pmid:21861203 |
Mohan A et al. | Role of peroxyacetic acid, octanoic acid, malic acid, and potassium lactate on the microbiological and instrumental color characteristics of ground beef. | 2012 | J. Food Sci. | pmid:22352902 |