MeSH term | MeSH ID | Detail |
---|---|---|
Drug-Related Side Effects and Adverse Reactions | D064420 | 3 associated lipids |
REM Sleep Behavior Disorder | D020187 | 1 associated lipids |
Dumping Syndrome | D004377 | 1 associated lipids |
octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.
To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with octanoic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Chen TM et al. | Effects of insulin on glucose uptake by rat hearts during and after coronary flow reduction. | 1997 | Am. J. Physiol. | pmid:9374750 |
Gann VK and Hardin CD | Acetate or octanoate increases glycogenolysis in smooth muscle as determined by 13C-NMR. | 1997 | Physiol Chem Phys Med NMR | pmid:9353955 |
Bito LZ et al. | Inhibition of in vitro concentrative prostaglandin accumulation by prostaglandins, prostaglandin analogues and by some inhibitors of organic anion transport. | 1976 | J. Physiol. (Lond.) | pmid:933072 |
Sheikh MI | Renal handling of phenol red. II. The mechanism of substituted phenolsulphophthalein (PSP) dye transport in rabbit kidney tubules in vitro. | 1976 | J. Physiol. (Lond.) | pmid:933027 |
Fowler JS et al. | Carbon-11 labeled aliphatic amines in lung uptake and metabolism studies: potential for dynamic measurements in vivo. | 1976 | J. Pharmacol. Exp. Ther. | pmid:933003 |
Coyle EF et al. | Fatty acid oxidation is directly regulated by carbohydrate metabolism during exercise. | 1997 | Am. J. Physiol. | pmid:9277379 |
Rabinowitz JL et al. | A method for serum octanoate in hepatic cirrhosis and hepatic encephalopathy. | 1977 | Clin. Chem. | pmid:923071 |
Leclercq P et al. | Inhibition of glycerol metabolism in hepatocytes isolated from endotoxic rats. | 1997 | Biochem. J. | pmid:9230136 |
Jones JG et al. | Determination of acetyl-CoA enrichment in rat heart and skeletal muscle by 1H nuclear magnetic resonance analysis of glutamate in tissue extracts. | 1997 | Anal. Biochem. | pmid:9212871 |
Zaleski J and Bryla J | Effects of oleate, palmitate, and octanoate on gluconeogenesis in isolated rabbit liver cells. | 1977 | Arch. Biochem. Biophys. | pmid:921276 |
Nakajima T et al. | The effect of carnitine on ketogenesis in perfused livers from juvenile visceral steatosis mice with systemic carnitine deficiency. | 1997 | Pediatr. Res. | pmid:9212045 |
Maes BD et al. | Gastric emptying rate of solids in patients with nonulcer dyspepsia. | 1997 | Dig. Dis. Sci. | pmid:9201077 |
Alcázar O et al. | Stimulation of islet protein kinase C translocation by palmitate requires metabolism of the fatty acid. | 1997 | Diabetes | pmid:9200650 |
Blatrix C et al. | [Properties of and information about a new preparation of immunoglobulins (IgGAM) enriched in IgA and IgM]. | 1977 | Rev. Fr. Transfus. Immunohematol. | pmid:918496 |
Pakula R et al. | Biosynthesis of medium-chain triacylglycerols and phospholipids by HepG-2 cells. | 1997 | Lipids | pmid:9168455 |
Abdel-aleem S et al. | Acute and chronic effects of adriamycin on fatty acid oxidation in isolated cardiac myocytes. | 1997 | J. Mol. Cell. Cardiol. | pmid:9140835 |
Amin D et al. | 1-Hydroxy-3-(methylpentylamino)-propylidene-1,1-bisphosphonic acid as a potent inhibitor of squalene synthase. | 1996 | Arzneimittelforschung | pmid:9125274 |
Sen CK et al. | Regulation of cellular thiols in human lymphocytes by alpha-lipoic acid: a flow cytometric analysis. | 1997 | Free Radic. Biol. Med. | pmid:9098099 |
Choi MG et al. | [13C]octanoic acid breath test for gastric emptying of solids: accuracy, reproducibility, and comparison with scintigraphy. | 1997 | Gastroenterology | pmid:9097998 |
Kunz D et al. | Flow cytometric detection of mitochondrial dysfunction in subpopulations of human mononuclear cells. | 1997 | Anal. Biochem. | pmid:9073359 |