MeSH term | MeSH ID | Detail |
---|---|---|
Drug-Related Side Effects and Adverse Reactions | D064420 | 3 associated lipids |
REM Sleep Behavior Disorder | D020187 | 1 associated lipids |
Dumping Syndrome | D004377 | 1 associated lipids |
octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.
To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with octanoic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Berne C | The effect of fatty acids and ketone bodies on the biosynthesis of insulin in isolated pancreatic islets of obese hyperglycemic mice. | 1975 | Horm. Metab. Res. | pmid:1102408 |
Pi-Sunyer FX | Effect of long- and medium-chain fatty acids on insulin secretion from pieces of rat pancreas. | 1975 | Proc. Soc. Exp. Biol. Med. | pmid:1144459 |
Taylor SI et al. | Regulation of pyruvate dehydrogenase in isolated rat liver mitochondria. Effects of octanoate, oxidation-reduction state, and adenosine triphosphate to adenosine diphosphate ratio. | 1975 | J. Biol. Chem. | pmid:1116996 |
Hansford RG and Johnson RN | The steady state concentrations of coenzyme A-SH and coenzyme A thioester, citrate, and isocitrate during tricarboxylate cycle oxidations in rabbit heart mitochondria. | 1975 | J. Biol. Chem. | pmid:1194259 |
Jomain-Baum M and Hanson RW | Regulation of hepatic gluconeogenesis in the guinea pig by fatty acids and ammonia. | 1975 | J. Biol. Chem. | pmid:1194271 |
Buse MG et al. | Regulation of branched-chain amino acid oxidation in isolated muscles, nerves and aortas of rats. | 1975 | Biochem. J. | pmid:1200982 |
Schmidt-Wilcke HA et al. | Effect of fatty acids on the stimulated gastric secretion in man. | 1975 | Digestion | pmid:1201821 |
Tangen O et al. | Platelet reactivity ex vivo and in vivo after acute and chronic treatment with sodium caprylate. | 1975 | Scand. J. Clin. Lab. Invest. | pmid:1129590 |
Fulks RM et al. | Effects of insulin, glucose, and amino acids on protein turnover in rat diaphragm. | 1975 | J. Biol. Chem. | pmid:1141208 |
Wilk PJ et al. | Failure of intestinal lymphatic block to prevent experimental hypercholesterolemia. | 1975 | Lymphology | pmid:1214506 |
Leovey EM and Andersen NH | Molecular basis of prostaglandin potency. II. Proton NMR studies of the conformation of prostaglandin F2alpha. | 1975 | Prostaglandins | pmid:1215541 |
Berne C | The metabolism of lipids in mouse pancreatic islets. The oxidation of fatty acids and ketone bodies. | 1975 | Biochem. J. | pmid:776173 |
Bach A et al. | Octanoate metabolism in the isolated perfused rat liver. II. Comparison with a long chain fatty acid. | 1975 | Arch. Int. Physiol. Biochim. | pmid:50825 |
Garner CW and Behal FJ | Effect of pH on substrate and inhibitor kinetic constants of human liver alanine aminopeptidase. Evidence for two ionizable active center groups. | 1975 | Biochemistry | pmid:38 |
Kurioka S et al. | Purification of fibrinogen using cationic detergent. | 1975 | J. Biochem. | pmid:805129 |
Hinson JA and Neal RA | An examination of octanol and octanal metabolism to octanoic acid by horse liver alcohol dehydrogenase. | 1975 | Biochim. Biophys. Acta | pmid:165828 |
Oshino N et al. | The properties of hydrogen peroxide production under hyperoxic and hypoxic conditions of perfused rat liver. | 1975 | Biochem. J. | pmid:167718 |
Maragoudakis ME et al. | Metabolism of octanoate and its effect on glucose and palmitate utilization by isolated fat cells. | 1975 | Proc. Soc. Exp. Biol. Med. | pmid:236573 |
Vincenzini MT et al. | In vivo effects of octanoate and oleate on glucose-6-phosphate dehydrogenase during germination of Pinus pinea seeds. | 1975 Nov-Dec | Ital. J. Biochem. | pmid:1218971 |
Reid ME et al. | Another potential source of error in Rh-hr typing. | 1975 Sep-Oct | Transfusion | pmid:812220 |
Guimbretiere J et al. | [A further case of albumin auto-agglutination in a blood donor]. | 1976 | Rev. Fr. Transfus. Immunohematol. | pmid:824703 |
Dijkstra FY and Wikén TO | Studies on mushroom flavours 2. Flavour compounds in coprinus comatus. | 1976 | Z Lebensm Unters Forsch | pmid:988687 |
Fowler JS et al. | Carbon-11 labeled aliphatic amines in lung uptake and metabolism studies: potential for dynamic measurements in vivo. | 1976 | J. Pharmacol. Exp. Ther. | pmid:933003 |
Sheikh MI | Renal handling of phenol red. II. The mechanism of substituted phenolsulphophthalein (PSP) dye transport in rabbit kidney tubules in vitro. | 1976 | J. Physiol. (Lond.) | pmid:933027 |
Bito LZ et al. | Inhibition of in vitro concentrative prostaglandin accumulation by prostaglandins, prostaglandin analogues and by some inhibitors of organic anion transport. | 1976 | J. Physiol. (Lond.) | pmid:933072 |
Harper RD and Saggerson ED | Factors affecting fatty acid oxidation in fat cells isolated from rat white adipose tissue. | 1976 | J. Lipid Res. | pmid:965842 |
Vinay P et al. | Effect of fatty acids on renal ammoniagenesis in in vivo and in vitro studies. | 1976 | Am. J. Physiol. | pmid:970471 |
Einarsson R | The binding of 1-anilino-8-naphthalenesulfonate, heparin, salicylate and caprylate by human antithrombin III. | 1976 | Biochim. Biophys. Acta | pmid:974107 |
Szekeres L et al. | Cardiac actions of arachidonic acid. | 1976 | Acta Biol. Med. Ger. | pmid:1007761 |
Parrilla R et al. | Use of endogenous triglycerides to support gluconeogenesis in the perfused isolated rat liver. | 1976 | Pflugers Arch. | pmid:1033522 |
Laurendeau G and Roy CC | Effect of cholestasis and biliary diversion on the absorption of Na octanoate in the rat. | 1976 | Experientia | pmid:1248600 |
Cheema-Dhadli S and Halperin ML | Effect of palmitoyl-CoA and beta-oxidation of fatty acids on the kinetics of mitochondrial citrate transporter. | 1976 | Can. J. Biochem. | pmid:1260499 |
Garratty G | Problems in pre-transfusion tests related to drugs and chemicals. | 1976 | Am J Med Technol | pmid:779471 |
Pettirossi O et al. | Prolongation of rat heart allograft survival by a synthetic progestogen (melengestrol acetate) and ara-cytidine acylates. | 1976 | Transplantation | pmid:775705 |
Derr RF and Zieve L | Effect of fatty acids on the disposition of ammonia. | 1976 | J. Pharmacol. Exp. Ther. | pmid:6789 |
Nieuwenhuizen W et al. | Purification and properties of two lipases from pig adipose tissue. | 1976 | Biochim. Biophys. Acta | pmid:7300 |
Lemieux G et al. | Glutamine synthetase and glutamyltransferase in the kidney of man, dog, and rat. | 1976 | Am. J. Physiol. | pmid:10736 |
Dobbins JW and Binder HJ | Effect of bile salts and fatty acids on the colonic absorption of oxalate. | 1976 | Gastroenterology | pmid:1269869 |
Lea MA et al. | Inhibition of glycolytic enzymes of rat liver and hepatomas by free fatty acids. | 1976 | Oncology | pmid:194194 |
Berger M et al. | Glucose metabolism in perfused skeletal muscle. Effects of starvation, diabetes, fatty acids, acetoacetate, insulin and exercise on glucose uptake and disposition. | 1976 | Biochem. J. | pmid:136249 |
Andreev LV and Temnov AV | [Determination of the specificity of microbial esterases in vivo]. | 1976 Jan-Feb | Mikrobiologiia | pmid:940489 |
Howard PL | Blood bank reagents: some problems related to preservatives and dyes. | 1976 Mar-Apr | Transfusion | pmid:1258119 |
Beck ML et al. | Serologic activity of fatty acid dependent antibodies in albumin-free systems. | 1976 Sep-Oct | Transfusion | pmid:982535 |
Ruderman NB et al. | Effect of starvation on muscle glucose metabolism: studies with the isolated perfused rat hindquarter. | 1977 | Fed. Proc. | pmid:838085 |
Rabinowitz JL et al. | A method for serum octanoate in hepatic cirrhosis and hepatic encephalopathy. | 1977 | Clin. Chem. | pmid:923071 |
Brodersen R and Hansen P | Bilirubin displacing effect of stabilizers added to injectable preparations of human serum albumin. | 1977 | Acta Paediatr Scand | pmid:557276 |
Carrella M and Dietschy JM | Comparison of the effects of cholic acid and chenic acid feeding on rates of cholesterol synthesis in the liver of the rat. | 1977 | Am J Dig Dis | pmid:857658 |
Bikhazi AB et al. | Calcium-prostaglandin aggregation and its effect on prostaglandin uptake by isolated rabbit intestine. | 1977 | J Pharm Sci | pmid:903871 |
Blatrix C et al. | [Properties of and information about a new preparation of immunoglobulins (IgGAM) enriched in IgA and IgM]. | 1977 | Rev. Fr. Transfus. Immunohematol. | pmid:918496 |
Zaleski J and Bryla J | Effects of oleate, palmitate, and octanoate on gluconeogenesis in isolated rabbit liver cells. | 1977 | Arch. Biochem. Biophys. | pmid:921276 |
Heaney-Kieras J and King TP | Limited pepsin digestion of human plasma albumin. | 1977 | J. Biol. Chem. | pmid:325004 |
Pérez-Diaz J et al. | Preparation and metabolic characterization of isolated rat lung cells. | 1977 | Biochimie | pmid:195638 |
Elliott KR and Pogson CI | Preparation and characterization of isolated parenchymal cells from guinea pig liver. | 1977 | Mol. Cell. Biochem. | pmid:196181 |
Fellenberg AJ and Pollard AC | A rapid and sensitive gas-liquid chromatographic procedure for the micro determination of sodium valproate (sodium di-N-propylacetate) in plasma or serum. | 1977 | Clin. Chim. Acta | pmid:338203 |
Dube VE et al. | Caprylate-dependent auto-anti-e. | 1977 | Vox Sang. | pmid:412322 |
Hossaini AA et al. | Experimental induction of caprylate-dependent albumin antibodies. | 1977 Jan-Feb | Transfusion | pmid:841674 |
Trimble ME et al. | Fatty acid transport and metabolism in the isolated perfused rat kidney. | 1977 Oct 23-26 | Curr Probl Clin Biochem | pmid:616371 |
Lemieux G et al. | Relationship between the renal metabolism of glutamine, fatty acids and ketone bodies. | 1977 Oct 23-26 | Curr Probl Clin Biochem | pmid:616372 |
Trauner DA and Huttenlocher PR | Short chain fatty acid-induced central hyperventilation in rabbits. | 1978 | Neurology | pmid:567765 |
Demol P and Sarles H | Action of fatty acids on the exocrine pancreatic secretion of the conscious rat: further evidence for a protein pancreatic inhibitory factor. | 1978 | J. Physiol. (Lond.) | pmid:633115 |
Hansford RG | Lipid oxidation by heart mitochondria from young adult and senescent rats. | 1978 | Biochem. J. | pmid:637843 |
Meisner H and Neet K | Competitive binding of long-chain free fatty acids, octanoate, and chlorophenoxyisobutyrate to albumin. | 1978 | Mol. Pharmacol. | pmid:642932 |
Mannaerts GP et al. | Hepatic fatty acid oxidation and ketogenesis after clofibrate treatment. | 1978 | Biochim. Biophys. Acta | pmid:656451 |
Scholz R et al. | The effect of fatty acids on the regulation of pyruvate dehydrogenase in perfused rat liver. | 1978 | Eur. J. Biochem. | pmid:658055 |
Rabinowitz JL et al. | Sources of serum [14C]-octanoate in cirrhosis of the liver and hepatic encephalopathy. | 1978 | J. Lab. Clin. Med. | pmid:621424 |
Kinnula VL and Hassinen I | Effect of chronic hypoxia on hepatic triacylglycerol concentration and mitochondrial fatty acid oxidizing capacity in liver and heart. | 1978 | Acta Physiol. Scand. | pmid:626089 |
Burns AH and Reddy WJ | Amino acid stimulation of oxygen and substrate utilization by cardiac myocytes. | 1978 | Am. J. Physiol. | pmid:727249 |
Fildes FJ and Oliver JE | Interaction of cortisol-21-palmitate with liposomes examined by differential scanning calorimetry. | 1978 | J. Pharm. Pharmacol. | pmid:26761 |
Sheikh MI et al. | On the mechanism of p-piperidyl and p-benzyl sulfamyl benzoic acids transport by renal tissue. | 1978 | Arch. Int. Physiol. Biochim. | pmid:87158 |
Rabinowitz JL et al. | The effects of intravenous sodium octanoate on the rhesus monkey. | 1978 | Am. J. Gastroenterol. | pmid:96693 |
Agostini C | Effect of sodium octanoate on leucine incorporation into protein of rat liver slices and of Yoshida ascites hepatoma cells. | 1978 | Experientia | pmid:203476 |
Miller TB | Cardiac performance of isolated perfused hearts from alloxan diabetic rats. | 1979 | Am. J. Physiol. | pmid:443443 |
Hulshoff A and Roseboom H | Determination of valproic acid (di-N-propyl acetic acid) in plasma by gas-liquid chromatography with pre-column butylation. | 1979 | Clin. Chim. Acta | pmid:373927 |
Andersen JM and Dietschy JM | Absolute rates of cholesterol synthesis in extrahepatic tissues measured with 3H-labeled water and 14C-labeled substrates. | 1979 | J. Lipid Res. | pmid:490050 |
Campillo JE et al. | Effect of oleic and octanoic acids on glucose-induced insulin release in vitro. | 1979 | Diabete Metab | pmid:499632 |
Valdivia MM et al. | [Effect of octanoic acid on the insulin secretion in response to glucose in vitro (author's transl)]. | 1979 | Rev. Esp. Fisiol. | pmid:504776 |
Skrede S and Slaattelid O | Fatty acid metabolism during hypothermic perfusion of the isolated dog kidney. | 1979 | Scand. J. Clin. Lab. Invest. | pmid:531496 |
Schröder K et al. | [Energy metabolism of the rat renal cortex, as measured by incubation in various substrates]. | 1979 | Acta Biol. Med. Ger. | pmid:543370 |
Staeffen J et al. | [Hyperoctanoatemia and the hepatic encephalopathy of cirrhosis. 150 dosages in 61 patients (author's transl)]. | 1979 | Nouv Presse Med | pmid:112576 |
Avenard G et al. | [The prevention of chickenpox in high risk children. Comparison of the effectiveness of specific immunoglobulins and of defibrinated convalescent plasma. 414 cases (author's transl)]. | 1979 | Nouv Presse Med | pmid:221885 |
Salesse R and Garnier J | Effects of drugs on pigeon erythrocyte membrane and asymmetric control or adenylate cyclase by the lipid bilayer. | 1979 | Biochim. Biophys. Acta | pmid:222319 |
Strong P et al. | Aerobic lactate synthesis by cardiac muscle. | 1979 | Eur. J. Biochem. | pmid:230966 |
Brady LJ et al. | Gluconeogenesis in isolated chicken (Gallus domesticus) liver cells. | 1979 | Comp. Biochem. Physiol., B | pmid:318406 |
Witters LA and Trasko CS | Regulation of hepatic free fatty acid metabolism by glucagon and insulin. | 1979 | Am. J. Physiol. | pmid:157075 |
Ring J et al. | Anaphylactoid reactions to infusions of plasma protein and human serum albumin. Role of aggregated proteins and of stabilizers added during production. | 1979 | Clin. Allergy | pmid:421339 |
Dhopeshwarkar GA and Subramanian C | Lipogenesis in the developing brain: utilization of radioactive leucine, isoleucine, octanoic acid and beta-hydroxybutyric acid. | 1979 | Lipids | pmid:423709 |
Trimble ME | Transport and metabolism of octanoate by the perfused rat kidney. | 1979 | Am. J. Physiol. | pmid:474762 |
Fischer JH et al. | Free fatty acid and glucose metabolism during hypothermic perfusion of canine kidneys. | 1979 | Eur Surg Res | pmid:488147 |
Lemieux G et al. | Effect of fluoroacetate on the inhibitory action of ketone bodies and fatty acids on renal ammoniagenesis. | 1979 | Am. J. Physiol. | pmid:464062 |
Spydevold O | The effect of octanoate and palmitate on the metabolism of valine in perfused hindquarter of rat. | 1979 | Eur. J. Biochem. | pmid:467425 |
Tanner GA et al. | Excretion of phenol red by the Necturus kidney. | 1979 | Am. J. Physiol. | pmid:443381 |
Morgenthaler JJ et al. | Fatty acid patterns during plasma fractionation. | 1980 | Vox Sang. | pmid:7415075 |
Schenk J et al. | Treatment of choledocholithiasis using the transpapillary perfusion technique. | 1980 | Endoscopy | pmid:7428727 |
Krisans SK et al. | Acyl-CoA synthetase in rat liver peroxisomes. Computer-assisted analysis of cell fractionation experiments. | 1980 | J. Biol. Chem. | pmid:7430088 |
Waymack PP et al. | Studies on the activation and inactivation of the branched chain alpha-keto acid dehydrogenase in the perfused rat heart. | 1980 | J. Biol. Chem. | pmid:7430101 |
Trauner DA | Regional cerebral Na+K+ ATPase activity following octanoate administration. | 1980 | Pediatr. Res. | pmid:6250122 |
Barth CA et al. | Morphology and metabolism of adult rat hepatocytes in primary culture. | 1980 | Hoppe-Seyler's Z. Physiol. Chem. | pmid:6997170 |
Caffier G et al. | The influence of free fatty acids on functional properties of isolated skeletal muscles. Octanoate action on membrane resistance. | 1980 | Pflugers Arch. | pmid:6966791 |
Kössler F et al. | Octanol and octanoate induced inhibition of the mechanical activity of isolated frog skeletal muscles. | 1980 | Chem. Biol. Interact. | pmid:6967777 |
Caffier G and Küchler G | [Effect of homologous n-alkanoic acids on the function of isolated skeletal muscles. IV. Effect of Na-octanoate on action potentials]. | 1980 | Acta Biol. Med. Ger. | pmid:6969509 |