octanoic acid

octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.

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Introduction

To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with octanoic acid?

octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with octanoic acid

MeSH term MeSH ID Detail
REM Sleep Behavior Disorder D020187 1 associated lipids
Flatulence D005414 1 associated lipids
Dumping Syndrome D004377 1 associated lipids
Snake Bites D012909 1 associated lipids
Chickenpox D002644 1 associated lipids
Esophageal Motility Disorders D015154 1 associated lipids
Severe Acute Respiratory Syndrome D045169 1 associated lipids
Chylothorax D002916 1 associated lipids
Hepatorenal Syndrome D006530 1 associated lipids
Prion Diseases D017096 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with octanoic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with octanoic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with octanoic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with octanoic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with octanoic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with octanoic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with octanoic acid

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Authors Title Published Journal PubMed Link
Miller TB Cardiac performance of isolated perfused hearts from alloxan diabetic rats. 1979 Am. J. Physiol. pmid:443443
Hollander D Retinol lymphatic and portal transport: influence of pH, bile, and fatty acids. 1980 Am. J. Physiol. pmid:7435575
Nesher R et al. Epitrochlearis muscle. II. Metabolic effects of contraction and catecholamines. 1980 Am. J. Physiol. pmid:7446724
Sarel I and Widmaier EP Stimulation of steroidogenesis in cultured rat adrenocortical cells by unsaturated fatty acids. 1995 Am. J. Physiol. pmid:7611525
Barbee RW et al. T3 treatment does not prevent myocardial dysfunction in chronically diabetic rats. 1988 Am. J. Physiol. pmid:2830793
Nutting CW et al. Vasorelaxant effects of short chain fatty acid salts in rat caudal artery. 1991 Am. J. Physiol. pmid:1877681
Patel TB Effect of sulfonylureas on hepatic fatty acid oxidation. 1986 Am. J. Physiol. pmid:3090894
Lemieux G et al. Glutamine synthetase and glutamyltransferase in the kidney of man, dog, and rat. 1976 Am. J. Physiol. pmid:10736
Matsumura T et al. O2 uptake in periportal and pericentral regions of liver lobule in perfused liver. 1986 Am. J. Physiol. pmid:3717341
Chacín J et al. Role of calcium in secretory and metabolic effects of substrates in the gastric mucosa. 1986 Am. J. Physiol. pmid:3090895
Coyle EF et al. Fatty acid oxidation is directly regulated by carbohydrate metabolism during exercise. 1997 Am. J. Physiol. pmid:9277379
Ben Cheikh R et al. Control of oxidative metabolism in volume-overloaded rat hearts: effects of different lipid substrates. 1994 Am. J. Physiol. pmid:8203607
Beaufrere B et al. Apparent decreased oxidation and turnover of leucine during infusion of medium-chain triglycerides. 1985 Am. J. Physiol. pmid:3895976
Barron JT et al. Substrate-dependent alteration in O2 consumption and energy metabolism in vascular smooth muscle. 1996 Am. J. Physiol. pmid:8764234
Werner JC et al. Fatty acid and glucose utilization in isolated, working fetal pig hearts. 1983 Am. J. Physiol. pmid:6869527
Chacín J et al. Role of fatty acid oxidation in mechanism of action of gastric secretagogues. 1980 Am. J. Physiol. pmid:6768310
Bielefeld DR et al. Altered sensitivity of chronic diabetic rat heart to calcium. 1983 Am. J. Physiol. pmid:6362427
Trimble ME Transport and metabolism of octanoate by the perfused rat kidney. 1979 Am. J. Physiol. pmid:474762
Lemieux G et al. Effect of fluoroacetate on the inhibitory action of ketone bodies and fatty acids on renal ammoniagenesis. 1979 Am. J. Physiol. pmid:464062
Tanner GA et al. Excretion of phenol red by the Necturus kidney. 1979 Am. J. Physiol. pmid:443381