octanoic acid

octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.

Cross Reference

Introduction

To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with octanoic acid?

octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with octanoic acid

MeSH term MeSH ID Detail
Chickenpox D002644 1 associated lipids
Esophageal Motility Disorders D015154 1 associated lipids
Severe Acute Respiratory Syndrome D045169 1 associated lipids
Chylothorax D002916 1 associated lipids
Hepatorenal Syndrome D006530 1 associated lipids
REM Sleep Behavior Disorder D020187 1 associated lipids
Flatulence D005414 1 associated lipids
Dumping Syndrome D004377 1 associated lipids
Snake Bites D012909 1 associated lipids
Prion Diseases D017096 2 associated lipids
Per page 10 20 50 100 | Total 73

PubChem Associated disorders and diseases

What pathways are associated with octanoic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with octanoic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with octanoic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with octanoic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with octanoic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with octanoic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with octanoic acid

Download all related citations
Per page 10 20 50 100 | Total 2110
Authors Title Published Journal PubMed Link
Wright TC et al. Inhibition of fatty acid synthesis in bovine mammary homogenate by palmitic acid is not a detergent effect. 2002 J. Dairy Sci. pmid:11949869
Giesy JG et al. Effect of dose of calcium salts of conjugated linoleic acid (CLA) on percentage and fatty acid content of milk fat in midlactation holstein cows. 2002 J. Dairy Sci. pmid:12214995
Dimenna GP and Emery RS Palmitate and octanoate metabolism in bovine mammary tissue. 1981 J. Dairy Sci. pmid:7264015
Nair MK et al. Antibacterial effect of caprylic acid and monocaprylin on major bacterial mastitis pathogens. 2005 J. Dairy Sci. pmid:16162522
van Zijderveld SM et al. Dietary inclusion of diallyl disulfide, yucca powder, calcium fumarate, an extruded linseed product, or medium-chain fatty acids does not affect methane production in lactating dairy cows. 2011 J. Dairy Sci. pmid:21605778
Morrill KM et al. Estimate of colostral immunoglobulin G concentration using refractometry without or with caprylic acid fractionation. 2012 J. Dairy Sci. pmid:22720953
Guidry AJ and O'Brien CN A method for measuring specific antibodies in bovine lacteal secretions during the nonlactating period. 1996 J. Dairy Sci. pmid:8792284
Tomita GM et al. Antigenic crossreactivity and lipopolysaccharide neutralization properties of bovine immunoglobulin G. 1995 J. Dairy Sci. pmid:8675757
Jaeggi JJ et al. Hard ewe's milk cheese manufactured from milk of three different groups of somatic cell counts. 2003 J. Dairy Sci. pmid:14594225
Morrill KM et al. Estimate of serum immunoglobulin G concentration using refractometry with or without caprylic acid fractionation. 2013 J. Dairy Sci. pmid:23664346
Fonseca CR et al. Storage of refrigerated raw goat milk affecting the quality of whole milk powder. 2013 J. Dairy Sci. pmid:23664351
Pera P et al. Influence of mastication on gastric emptying. 2002 J. Dent. Res. pmid:11876271
Nohara S et al. Gastric emptying in patients with Type 2 diabetes mellitus and diabetes associated with mitochondrial DNA 3243 mutation using 13C-octanoic acid breath test. 2006 Sep-Oct J. Diabetes Complicat. pmid:16949516
Gravena C et al. Acute effects of fatty acids on insulin secretion from rat and human islets of Langerhans. 2002 J. Endocrinol. pmid:11927386
Yoshida Y et al. Reye syndrome: rate of oxidation of fatty acids in leukocytes and serum levels of lipid peroxides. 1989 J. Exp. Pathol. pmid:2769452
Singh AK et al. Effect of fatty acids and their derivatives on mitochondrial structures. 1989 J. Exp. Pathol. pmid:2778551
Moschonas G et al. Antimicrobials for reduction of Salmonella contamination in uncooked, surface-browned breaded chicken products. 2012 J. Food Prot. pmid:22691468
Burnett SL et al. Use of octanoic acid as a postlethality treatment to reduce Listeria monocytogenes on ready-to-eat meat and poultry products. 2007 J. Food Prot. pmid:17340874
Nair MK et al. Inactivation of Enterobacter sakazakii in reconstituted infant formula by monocaprylin. 2004 J. Food Prot. pmid:15633694
Amalaradjou MA et al. Inactivation of escherichia coli O157:H7 in cattle drinking water by sodium caprylate. 2006 J. Food Prot. pmid:16995532
Nair MK et al. Antibacterial effect of monocaprylin on Escherichia coli O157:H7 in apple juice. 2005 J. Food Prot. pmid:16161689
Annamalai T et al. In vitro inactivation of Escherichia coli O157:H7 in bovine rumen fluid by caprylic acid. 2004 J. Food Prot. pmid:15151222
Brandt AL et al. Synergistic inhibition of Listeria monocytogenes in vitro through the combination of octanoic acid and acidic calcium sulfate. 2011 J. Food Prot. pmid:21219773
Baskaran SA et al. Inactivation of Escherichia coli O157:H7 on cattle hides by caprylic acid and β-resorcylic acid. 2013 J. Food Prot. pmid:23433381
Johny AK et al. Prophylactic supplementation of caprylic acid in feed reduces Salmonella enteritidis colonization in commercial broiler chicks. 2009 J. Food Prot. pmid:19435218
Solís de los Santos F et al. Caprylic Acid reduces enteric campylobacter colonization in market-aged broiler chickens but does not appear to alter cecal microbial populations. 2010 J. Food Prot. pmid:20132669
Mohan A et al. Inactivation of Bacillus atrophaeus spores with surface-active peracids and characterization of formed free radicals using electron spin resonance spectroscopy. 2009 J. Food Sci. pmid:19895489
Vazquez-Cruz MA et al. Effect of maturity stage and storage on flavor compounds and sensory description of berrycactus (Myrtillocactus geometrizans). 2012 J. Food Sci. pmid:22429085
Antón MJ et al. Aromatic profile of ciders by chemical quantitative, gas chromatography-olfactometry, and sensory analysis. 2014 J. Food Sci. pmid:24313985
Hines JD et al. Inappropriate use of D-values for determining biocidal activity of various antimicrobials. 2011 Jan-Feb J. Food Sci. pmid:21535698
Zhang S et al. Influence of pulsed electric field treatments on the volatile compounds of milk in comparison with pasteurized processing. J. Food Sci. pmid:21535640
Zhang M et al. Comparative study of aromatic compounds in young red wines from cabernet sauvignon, cabernet franc, and cabernet gernischet varieties in China. 2007 J. Food Sci. pmid:17995710
Mohan A et al. Role of peroxyacetic acid, octanoic acid, malic acid, and potassium lactate on the microbiological and instrumental color characteristics of ground beef. 2012 J. Food Sci. pmid:22352902
Moschonas G et al. Activity of caprylic acid, carvacrol, ε-polylysine and their combinations against Salmonella in not-ready-to-eat surface-browned, frozen, breaded chicken products. 2012 J. Food Sci. pmid:22670620
Matsumoto M et al. Gastric emptying in diabetic patients by the (13)C-octanoic acid breath test: role of insulin in gastric motility. 2007 J. Gastroenterol. pmid:17671762
Sanaka M et al. Effect of cigarette smoking on gastric emptying of solids in Japanese smokers: a crossover study using the 13C-octanoic acid breath test. 2005 J. Gastroenterol. pmid:16007391
Sanaka M et al. Assessment of the gastric emptying velocity by the 13C-octanoate breath test: deconvolution versus a Wagner-Nelson analysis. 2006 J. Gastroenterol. pmid:16933000
Chen CP et al. Infrared spectrometry based 13C-octanoic acid breath test in measuring human solid gastric emptying. 2003 J. Gastroenterol. Hepatol. pmid:12519222
Kachi M et al. Effects of Helicobacter pylori eradication therapy on gastric emptying measured using the 13C-octanoic acid breath test and the acetaminophen method. 2006 J. Gastroenterol. Hepatol. pmid:16704530
Hellmig S et al. Gastric emptying time of fluids and solids in healthy subjects determined by 13C breath tests: influence of age, sex and body mass index. 2006 J. Gastroenterol. Hepatol. pmid:17074022
Viegas CA and Sá-Correia I Activation of plasma membrane ATPase of Saccharomyces cerevisiae by octanoic acid. 1991 J. Gen. Microbiol. pmid:1827836
Jones DB et al. Hepatic encephalopathy. Application of visual evoked responses to test hypotheses of its pathogenesis in rats. 1987 J. Hepatol. pmid:3033057
Russo C et al. Re.: Purification of IgG monoclonal antibody by caprylic acid precipitation. 1983 J. Immunol. Methods pmid:6655243
McKinney MM and Parkinson A A simple, non-chromatographic procedure to purify immunoglobulins from serum and ascites fluid. 1987 J. Immunol. Methods pmid:3805742
Ogden JR and Leung K Purification of murine monoclonal antibodies by caprylic acid. 1988 J. Immunol. Methods pmid:3397551
McLaren RD et al. The use of caprylic acid for the extraction of the immunoglobulin fraction from egg yolk of chickens immunised with ovine alpha-lactalbumin. 1994 J. Immunol. Methods pmid:7822824
Reik LM et al. A simple, non-chromatographic purification procedure for monoclonal antibodies. Isolation of monoclonal antibodies against cytochrome P450 isozymes. 1987 J. Immunol. Methods pmid:3598193
Raweerith R and Ratanabanangkoon K Fractionation of equine antivenom using caprylic acid precipitation in combination with cationic ion-exchange chromatography. 2003 J. Immunol. Methods pmid:14604541
Temponi M et al. Immunoreactivity and affinity of murine IgG monoclonal antibodies purified by caprylic acid precipitation. 1988 J. Immunol. Methods pmid:3192945
Perosa F et al. Purification of human immunoglobulins by sequential precipitation with caprylic acid and ammonium sulphate. 1990 J. Immunol. Methods pmid:2324507
Al-Abdulla I et al. Single-reagent one-step procedures for the purification of ovine IgG, F(ab')2 and Fab antivenoms by caprylic acid. 2014 J. Immunol. Methods pmid:24246428
Ciesielski S et al. The influence of nitrogen limitation on mcl-PHA synthesis by two newly isolated strains of Pseudomonas sp. 2010 J. Ind. Microbiol. Biotechnol. pmid:20204456
Hu F and You S Inactivation of type I polyhydroxyalkanoate synthase in Aeromonas hydrophila resulted in discovery of another potential PHA synthase. 2007 J. Ind. Microbiol. Biotechnol. pmid:17043804
Schmidt SP et al. Toxic response caused by a misfolding variant of the mitochondrial protein short-chain acyl-CoA dehydrogenase. 2011 J. Inherit. Metab. Dis. pmid:21170680
Duran M et al. The differential diagnosis of dicarboxylic aciduria. 1984 J. Inherit. Metab. Dis. pmid:6434845
Shen JJ et al. Acylcarnitines in fibroblasts of patients with long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency and other fatty acid oxidation disorders. 2000 J. Inherit. Metab. Dis. pmid:10682306
Hoffmann GF et al. Physiology and pathophysiology of organic acids in cerebrospinal fluid. 1993 J. Inherit. Metab. Dis. pmid:8412012
Wanders RJ et al. Octanoate and palmitate beta-oxidation in human leukocytes: implications for the rapid diagnosis of fatty acid beta-oxidation disorders. 1991 J. Inherit. Metab. Dis. pmid:1770782
Heales SJ et al. Rapid diagnosis of medium-chain acyl CoA dehydrogenase deficiency by measurement of cis-4-decenoic acid in plasma. 1991 J. Inherit. Metab. Dis. pmid:1779611
Albers S et al. Compound heterozygosity in four asymptomatic siblings with medium-chain acyl-CoA dehydrogenase deficiency. 2001 J. Inherit. Metab. Dis. pmid:11486912
Scholte HR et al. Assessment of deficiencies of fatty acyl-CoA dehydrogenases in fibroblasts, muscle and liver. 1992 J. Inherit. Metab. Dis. pmid:1405467
Rabinowitz JL et al. Sources of serum [14C]-octanoate in cirrhosis of the liver and hepatic encephalopathy. 1978 J. Lab. Clin. Med. pmid:621424
Zieve L et al. Brain methanethiol and ammonia concentrations in experimental hepatic coma and coma induced by injections of various combinations of these substances. 1984 J. Lab. Clin. Med. pmid:6491466
Zieve L et al. Hepatic failure toxins depress liver regenerative enzymes after periportal injury with allyl alcohol in the rat. 1988 J. Lab. Clin. Med. pmid:3373115
Zieve L and Dozeman R Effect of hepatic failure toxins on regenerative enzymes in the liver after injury with galactosamine in the rat. 1989 J. Lab. Clin. Med. pmid:2703758
Zieve L et al. Effect of hepatic failure toxins on liver thymidine kinase activity and ornithine decarboxylase activity after massive necrosis with acetaminophen in the rat. 1985 J. Lab. Clin. Med. pmid:4056569
Windus-Podehl G et al. Encephalopathic effect of phenol in rats. 1983 J. Lab. Clin. Med. pmid:6833829
Zieve L et al. Toxicity of a fatty acid and ammonia: interactions with hypoglycemia and Krebs cycle inhibition. 1983 J. Lab. Clin. Med. pmid:6343534
Andersen JM and Dietschy JM Absolute rates of cholesterol synthesis in extrahepatic tissues measured with 3H-labeled water and 14C-labeled substrates. 1979 J. Lipid Res. pmid:490050
Harper RD and Saggerson ED Factors affecting fatty acid oxidation in fat cells isolated from rat white adipose tissue. 1976 J. Lipid Res. pmid:965842
Demizieux L et al. Conjugated linoleic acid isomers in mitochondria: evidence for an alteration of fatty acid oxidation. 2002 J. Lipid Res. pmid:12454273
Sallee VL et al. Determination of unidirectional uptake rates for lipids across the intestinal brush border. 1972 J. Lipid Res. pmid:5016300
Clark SB The uptake of oleic acid by rat small intestine: a comparison of methodologies. 1971 J. Lipid Res. pmid:5542704
Hillgartner FB and Charron T Arachidonate and medium-chain fatty acids inhibit transcription of the acetyl-CoA carboxylase gene in hepatocytes in culture. 1997 J. Lipid Res. pmid:9458278
Lockridge JB et al. Bioinformatic profiling of the transcriptional response of adult rat cardiomyocytes to distinct fatty acids. 2008 J. Lipid Res. pmid:18387886
Trotter PJ et al. Fatty acid uptake by Caco-2 human intestinal cells. 1996 J. Lipid Res. pmid:9026531
Rodriguez M et al. Plasma fatty acids and [13C]linoleic acid metabolism in preterm infants fed a formula with medium-chain triglycerides. 2003 J. Lipid Res. pmid:12518021
Kenyon MA and Hamilton JA 13C NMR studies of the binding of medium-chain fatty acids to human serum albumin. 1994 J. Lipid Res. pmid:8014580
Castellani LW et al. Mechanisms mediating insulin resistance in transgenic mice overexpressing mouse apolipoprotein A-II. 2004 J. Lipid Res. pmid:15466364
Nicolosi RJ et al. Effects of specific fatty acids (8:0, 14:0, cis-18:1, trans-18:1) on plasma lipoproteins, early atherogenic potential, and LDL oxidative properties in the hamster. 1998 J. Lipid Res. pmid:9788243
Stange EF and Dietschy JM Absolute rates of cholesterol synthesis in rat intestine in vitro and in vivo: a comparison of different substrates in slices and isolated cells. 1983 J. Lipid Res. pmid:6833883
Kemp-Harper R et al. Sodium ions in ordered environments in biological systems: analysis of 23Na NMR spectra. 1999 J. Magn. Reson. pmid:10497043
Samant MP et al. Novel analogues of degarelix incorporating hydroxy-, methoxy-, and pegylated-urea moieties at positions 3, 5, 6 and the N-terminus. Part III. 2006 J. Med. Chem. pmid:16759096
Wu C and Sun B Identification of novel esterase from metagenomic library of Yangtze river. 2009 J. Microbiol. Biotechnol. pmid:19307769
Wu HA et al. Rapid differentiation between short-chain-length and medium-chain-length polyhydroxyalkanoate-accumulating bacteria with spectrofluorometry. 2003 J. Microbiol. Methods pmid:12609733
Kragh-Hansen U et al. Chain length-dependent binding of fatty acid anions to human serum albumin studied by site-directed mutagenesis. 2006 J. Mol. Biol. pmid:16979183
Guy JE et al. The structure of an alcohol dehydrogenase from the hyperthermophilic archaeon Aeropyrum pernix. 2003 J. Mol. Biol. pmid:12927540
Abdel-aleem S et al. Acute and chronic effects of adriamycin on fatty acid oxidation in isolated cardiac myocytes. 1997 J. Mol. Cell. Cardiol. pmid:9140835
Kochel PJ et al. Effects of noncarbohydrate substrates on protein synthesis in hearts from fed and fasted rats. 1984 J. Mol. Cell. Cardiol. pmid:6374161
Señarís RM et al. Effects of free fatty acids on somatostatin secretion, content and mRNA levels in cortical and hypothalamic fetal rat neurones in monolayer culture. 1993 J. Mol. Endocrinol. pmid:8097916
Bayer S et al. Indication for a new lipolytic enzyme family: isolation and characterization of two esterases from a metagenomic library. 2010 J. Mol. Microbiol. Biotechnol. pmid:20530969
Ida T et al. Purification and characterization of caprine ghrelin and its effect on growth hormone release. 2010 J. Mol. Neurosci. pmid:20437258
Liu Y and Nair MG An efficient and economical MTT assay for determining the antioxidant activity of plant natural product extracts and pure compounds. 2010 J. Nat. Prod. pmid:20565070
Nosek TM and Crosland MB Calcium-dependent proteolysis in neural tissue is activated at physiologic intracellular Ca2+ levels and inhibited by some anticonvulsants. 1983 J. Neurobiol. pmid:6298363
Murtuza MI and Isokawa M Endogenous ghrelin-O-acyltransferase (GOAT) acylates local ghrelin in the hippocampus. 2018 J. Neurochem. pmid:29063591
Auestad N et al. Fatty acid oxidation and ketogenesis by astrocytes in primary culture. 1991 J. Neurochem. pmid:2002348
Reichmann H et al. Enzymes of fatty acid beta-oxidation in developing brain. 1988 J. Neurochem. pmid:2899130
Kim CS et al. Octanoic acid produces accumulation of monoamine acidic metabolites in the brain: interaction with organic anion transport at the choroid plexus. 1992 J. Neurochem. pmid:1372345
Gibbs ME et al. Rescue of Abeta(1-42)-induced memory impairment in day-old chick by facilitation of astrocytic oxidative metabolism: implications for Alzheimer's disease. 2009 J. Neurochem. pmid:19393032
Olson JE et al. Octanoic acid inhibits astrocyte volume control: implications for cerebral edema in Reye's syndrome. 1989 J. Neurochem. pmid:2538563