octanoic acid

octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.

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Introduction

To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with octanoic acid?

octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with octanoic acid

MeSH term MeSH ID Detail
Snake Bites D012909 1 associated lipids
Dumping Syndrome D004377 1 associated lipids
Esophageal Motility Disorders D015154 1 associated lipids
Chickenpox D002644 1 associated lipids
Severe Acute Respiratory Syndrome D045169 1 associated lipids
Chylothorax D002916 1 associated lipids
Hepatorenal Syndrome D006530 1 associated lipids
Flatulence D005414 1 associated lipids
REM Sleep Behavior Disorder D020187 1 associated lipids
Prion Diseases D017096 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with octanoic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with octanoic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with octanoic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with octanoic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with octanoic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with octanoic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with octanoic acid

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Authors Title Published Journal PubMed Link
Tack J et al. Influence of delaying gastric emptying on meal-related symptoms in healthy subjects. 2006 Aliment. Pharmacol. Ther. pmid:16984498
Maes BD et al. Influence of octreotide on the gastric emptying of solids and liquids in normal healthy subjects. 1995 Aliment. Pharmacol. Ther. pmid:7766738
Gourcerol G et al. Impaired fasting pyloric compliance in gastroparesis and the therapeutic response to pyloric dilatation. 2015 Aliment. Pharmacol. Ther. pmid:25523288
Carrella M and Dietschy JM Comparison of the effects of cholic acid and chenic acid feeding on rates of cholesterol synthesis in the liver of the rat. 1977 Am J Dig Dis pmid:857658
Shah S Pharmacy considerations for the use of IGIV therapy. 2005 Am J Health Syst Pharm pmid:16100386
Garratty G Problems in pre-transfusion tests related to drugs and chemicals. 1976 Am J Med Technol pmid:779471
Jandacek RJ et al. The rapid hydrolysis and efficient absorption of triglycerides with octanoic acid in the 1 and 3 positions and long-chain fatty acid in the 2 position. 1987 Am. J. Clin. Nutr. pmid:3578095
Yamamoto Y et al. Rapid alternative absorption of dietary long-chain fatty acids with upregulation of intestinal glycosylated CD36 in liver cirrhosis. 2012 Am. J. Clin. Nutr. pmid:22648712
Robertson MD et al. Acute ingestion of a meal rich in n-3 polyunsaturated fatty acids results in rapid gastric emptying in humans. 2002 Am. J. Clin. Nutr. pmid:12081840
Robinson MK et al. A two-center study of the development of acute irritation responses to fatty acids. 1999 Am. J. Contact Dermatitis pmid:10444106
Talley NJ et al. Can symptoms discriminate among those with delayed or normal gastric emptying in dysmotility-like dyspepsia? 2001 Am. J. Gastroenterol. pmid:11374677
Vanheel H et al. Pathophysiological Abnormalities in Functional Dyspepsia Subgroups According to the Rome III Criteria. 2017 Am. J. Gastroenterol. pmid:27958284
Lee JS et al. Toward office-based measurement of gastric emptying in symptomatic diabetics using [13C]octanoic acid breath test. 2000 Am. J. Gastroenterol. pmid:11051344
Cappello G et al. Gastric emptying of a solid-liquid meal measured with 13C octanoic acid breath test and real-time ultrasonography: a comparative study. 2000 Am. J. Gastroenterol. pmid:11095323
Rabinowitz JL et al. The effects of intravenous sodium octanoate on the rhesus monkey. 1978 Am. J. Gastroenterol. pmid:96693
Choi MG et al. Reproducibility and simplification of 13C-octanoic acid breath test for gastric emptying of solids. 1998 Am. J. Gastroenterol. pmid:9448183
Miele L et al. Hepatic mitochondrial beta-oxidation in patients with nonalcoholic steatohepatitis assessed by 13C-octanoate breath test. 2003 Am. J. Gastroenterol. pmid:14572600
Perri F et al. Patterns of symptoms in functional dyspepsia: role of Helicobacter pylori infection and delayed gastric emptying. 1998 Am. J. Gastroenterol. pmid:9820377
REICH WJ et al. The treatment of monilial vaginitis with caprylic acid. 1953 Am. J. Obstet. Gynecol. pmid:13016687
REES ED and KLINE DL Metabolism of octanoate by fatty liver slices. 1957 Am. J. Physiol. pmid:13470069