octanoic acid

octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.

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Introduction

To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with octanoic acid?

octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with octanoic acid

MeSH term MeSH ID Detail
Hepatorenal Syndrome D006530 1 associated lipids
REM Sleep Behavior Disorder D020187 1 associated lipids
Flatulence D005414 1 associated lipids
Dumping Syndrome D004377 1 associated lipids
Snake Bites D012909 1 associated lipids
Chickenpox D002644 1 associated lipids
Esophageal Motility Disorders D015154 1 associated lipids
Severe Acute Respiratory Syndrome D045169 1 associated lipids
Chylothorax D002916 1 associated lipids
Gastroparesis D018589 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with octanoic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with octanoic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with octanoic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with octanoic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with octanoic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with octanoic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with octanoic acid

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Authors Title Published Journal PubMed Link
Zhu L et al. Simultaneous sampling of volatile and non-volatile analytes in beer for fast fingerprinting by extractive electrospray ionization mass spectrometry. 2010 Anal Bioanal Chem pmid:20644917
Takahashi H et al. Metabolomics approach for determining growth-specific metabolites based on Fourier transform ion cyclotron resonance mass spectrometry. 2008 Anal Bioanal Chem pmid:18560811
Eggink M et al. Targeted LC-MS derivatization for aldehydes and carboxylic acids with a new derivatization agent 4-APEBA. 2010 Anal Bioanal Chem pmid:20238107
Yamamoto K et al. An LC method for monitoring medium-chain fatty acid permeation through CaCo-2 cell monolayers. 2009 Anal Bioanal Chem pmid:19641905
Urquiza M et al. α-Helix peptides designed from EBV-gH protein display higher antigenicity and induction of monocyte apoptosis than the native peptide. 2010 Amino Acids pmid:20473772
McLellan J et al. Comparison of the carbon 13-labeled octanoic acid breath test and ultrasonography for assessment of gastric emptying of a semisolid meal in dogs. 2004 Am. J. Vet. Res. pmid:15566095
Wyse CA et al. Use of the 13C-octanoic acid breath test for assessment of solid-phase gastric emptying in dogs. 2001 Am. J. Vet. Res. pmid:11763185
Valipe SR et al. In vitro antimicrobial properties of caprylic acid, monocaprylin, and sodium caprylate against Dermatophilus congolensis. 2011 Am. J. Vet. Res. pmid:21355735
Battiprolu PK et al. Sex differences in energy metabolism and performance of teleost cardiac tissue. 2007 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:17038442
Richards JG et al. Palmitate movement across red and white muscle membranes of rainbow trout. 2004 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:12969874
El Hafidi M et al. Glycine intake decreases plasma free fatty acids, adipose cell size, and blood pressure in sucrose-fed rats. 2004 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:15331379
Librán-Pérez M et al. Evidence of a metabolic fatty acid-sensing system in the hypothalamus and Brockmann bodies of rainbow trout: implications in food intake regulation. 2012 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:22496361
Sallam HS et al. Mechanisms of burn-induced impairment in gastric slow waves and emptying in rats. 2010 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:20427716
Darling RA et al. Mercaptoacetate and fatty acids exert direct and antagonistic effects on nodose neurons via GPR40 fatty acid receptors. 2014 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:24760994
Degen L et al. Effect of CCK-1 receptor blockade on ghrelin and PYY secretion in men. 2007 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:17138722
Barron JT and Gu L Energetic effects of adenosine on vascular smooth muscle. 2000 Am. J. Physiol. Heart Circ. Physiol. pmid:10644580
Panchal AR et al. Partitioning of pyruvate between oxidation and anaplerosis in swine hearts. 2000 Am. J. Physiol. Heart Circ. Physiol. pmid:11045976
Longnus SL et al. Regulation of myocardial fatty acid oxidation by substrate supply. 2001 Am. J. Physiol. Heart Circ. Physiol. pmid:11557544
Labarthe F et al. Fatty acid oxidation and its impact on response of spontaneously hypertensive rat hearts to an adrenergic stress: benefits of a medium-chain fatty acid. 2005 Am. J. Physiol. Heart Circ. Physiol. pmid:15550523
Kajimoto M et al. Differential effects of octanoate and heptanoate on myocardial metabolism during extracorporeal membrane oxygenation in an infant swine model. 2015 Am. J. Physiol. Heart Circ. Physiol. pmid:26232235