octanoic acid

octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.

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Introduction

To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with octanoic acid?

octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with octanoic acid

MeSH term MeSH ID Detail
Body Weight D001835 333 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Edema D004487 152 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Hemolysis D006461 131 associated lipids
Inflammation D007249 119 associated lipids
Glioma D005910 112 associated lipids
Insulin Resistance D007333 99 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Per page 10 20 50 100 | Total 73

PubChem Associated disorders and diseases

What pathways are associated with octanoic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with octanoic acid?

Related references are published most in these journals:

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What functions are associated with octanoic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with octanoic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with octanoic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with octanoic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with octanoic acid

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Authors Title Published Journal PubMed Link
Yang H et al. Enhancing the stereoselectivity and activity of Candida species lipase in organic solvent by noncovalent enzyme modification. 1996 Ann. N. Y. Acad. Sci. pmid:8958099
Katoh K et al. Octanoate increases cytosolic Ca2+ concentration and membrane conductance in ovine pancreatic acinar cells. 1996 J. Comp. Physiol. B, Biochem. Syst. Environ. Physiol. pmid:8923746
Guthy E Enteric-coated fish oil in Crohn's disease. 1996 N. Engl. J. Med. pmid:8927072
Bojes HK and Thurman RG Potent peroxisome proliferators inhibit beta-oxidation in the isolated perfused rat liver. 1996 Toxicol. Appl. Pharmacol. pmid:8887448
Sidossis LS et al. Glucose plus insulin regulate fat oxidation by controlling the rate of fatty acid entry into the mitochondria. 1996 J. Clin. Invest. pmid:8941640
Veereman-Wauters G et al. The 13C-octanoic acid breath test: a noninvasive technique to assess gastric emptying in preterm infants. 1996 J. Pediatr. Gastroenterol. Nutr. pmid:8856575
Fulgencio JP et al. Troglitazone inhibits fatty acid oxidation and esterification, and gluconeogenesis in isolated hepatocytes from starved rats. 1996 Diabetes pmid:8866561
Cave AC et al. A model of anoxic preconditioning in the isolated rat cardiac myocyte. Importance of adenosine and insulin. 1996 May-Jun Basic Res. Cardiol. pmid:8831940
Nakajima T et al. The effect of carnitine on ketogenesis in perfused livers from juvenile visceral steatosis mice with systemic carnitine deficiency. 1997 Pediatr. Res. pmid:9212045
Hillgartner FB and Charron T Arachidonate and medium-chain fatty acids inhibit transcription of the acetyl-CoA carboxylase gene in hepatocytes in culture. 1997 J. Lipid Res. pmid:9458278
Maes BD et al. Gastric emptying rate of solids in patients with nonulcer dyspepsia. 1997 Dig. Dis. Sci. pmid:9201077
Barron JT et al. Oxidation of acetate and octanoate and its relation to glucose metabolism in contracting porcine carotid artery. 1997 Biochim. Biophys. Acta pmid:9452767
Guillot E et al. Octanoate metabolism in primary culture of chicken hepatocytes: evidence for high-capacity octanoate esterification. 1997 Comp. Biochem. Physiol. B, Biochem. Mol. Biol. pmid:9440218
Coyle EF et al. Fatty acid oxidation is directly regulated by carbohydrate metabolism during exercise. 1997 Am. J. Physiol. pmid:9277379
Jones JG et al. Determination of acetyl-CoA enrichment in rat heart and skeletal muscle by 1H nuclear magnetic resonance analysis of glutamate in tissue extracts. 1997 Anal. Biochem. pmid:9212871
Leclercq P et al. Inhibition of glycerol metabolism in hepatocytes isolated from endotoxic rats. 1997 Biochem. J. pmid:9230136
Alcázar O et al. Stimulation of islet protein kinase C translocation by palmitate requires metabolism of the fatty acid. 1997 Diabetes pmid:9200650
Choi MG et al. [13C]octanoic acid breath test for gastric emptying of solids: accuracy, reproducibility, and comparison with scintigraphy. 1997 Gastroenterology pmid:9097998
Sen CK et al. Regulation of cellular thiols in human lymphocytes by alpha-lipoic acid: a flow cytometric analysis. 1997 Free Radic. Biol. Med. pmid:9098099
Schadewaldt P et al. Application of isotope-selective nondispersive infrared spectrometry (IRIS) for evaluation of [13C]octanoic acid gastric-emptying breath tests: comparison with isotope ratio-mass spectrometry (IRMS). 1997 Clin. Chem. pmid:9068597
Kunz D et al. Flow cytometric detection of mitochondrial dysfunction in subpopulations of human mononuclear cells. 1997 Anal. Biochem. pmid:9073359
Abdel-aleem S et al. Acute and chronic effects of adriamycin on fatty acid oxidation in isolated cardiac myocytes. 1997 J. Mol. Cell. Cardiol. pmid:9140835
Viegas CA and Sá-Correia I Effects of low temperatures (9-33 degrees C) and pH (3.3-5.7) in the loss of Saccharomyces cerevisiae viability by combining lethal concentrations of ethanol with octanoic and decanoic acids. 1997 Int. J. Food Microbiol. pmid:9039572
Priestman DA et al. Inhibition of pyruvate dehydrogenase kinase by pyruvate in cultured cardiac myocytes. 1997 Biochem. Soc. Trans. pmid:9056999
Chen TM et al. Effects of insulin on glucose uptake by rat hearts during and after coronary flow reduction. 1997 Am. J. Physiol. pmid:9374750
Gann VK and Hardin CD Acetate or octanoate increases glycogenolysis in smooth muscle as determined by 13C-NMR. 1997 Physiol Chem Phys Med NMR pmid:9353955
Pakula R et al. Biosynthesis of medium-chain triacylglycerols and phospholipids by HepG-2 cells. 1997 Lipids pmid:9168455
Amlou M et al. Larval tolerance in the Drosophila melanogaster species complex toward the two toxic acids of the D. sechellia host plant. 1998 Hereditas pmid:9868925
Bardi L et al. Esterase activity and release of ethyl esters of medium-chain fatty acids by Saccharomyces cerevisiae during anaerobic growth. 1998 Can. J. Microbiol. pmid:10347863
Wang H and Xie X [Effect of varied sample treatment procedures on detection of hepatitis B virus DNA]. 1998 Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi pmid:12515203
Amlou M et al. Genetic analysis of Drosophila sechellia specialization: oviposition behavior toward the major aliphatic acids of its host plant. 1998 Behav. Genet. pmid:9926614
Schmeisch AP et al. The role of hemodynamics in the action of diltiazem on hepatic fatty acid metabolism. 1998 Res. Commun. Mol. Pathol. Pharmacol. pmid:10342914
Perri F et al. 13C-octanoic acid breath test: a reliable tool for measuring gastric emptying. 1998 Ital J Gastroenterol Hepatol pmid:9675662
Ninomiya Y and Kayama Y Inhibition of choline acetyltransferase activity by serum albumin modified with octanoic acid and other fatty acids. 1998 Neurochem. Res. pmid:9804287
Maes BD et al. Gastric emptying flow curves separated from carbon-labeled octanoic acid breath test results. 1998 Am. J. Physiol. pmid:9655697
Choi MG et al. Reproducibility and simplification of 13C-octanoic acid breath test for gastric emptying of solids. 1998 Am. J. Gastroenterol. pmid:9448183
Visarius TM et al. Thiodiglycolic acid is excreted by humans receiving ifosfamide and inhibits mitochondrial function in rats. 1998 Drug Metab. Dispos. pmid:9492379
Viegas CA et al. The H(+)-ATPase in the plasma membrane of Saccharomyces cerevisiae is activated during growth latency in octanoic acid-supplemented medium accompanying the decrease in intracellular pH and cell viability. 1998 Appl. Environ. Microbiol. pmid:9464423
Abdel-aleem S et al. Regulation of carbohydrate and fatty acid utilization by L-carnitine during cardiac development and hypoxia. 1998 Mol. Cell. Biochem. pmid:9546635
Maes BD et al. 13C-Octanoic acid breath test for gastric emptying rate of solids. 1998 Gastroenterology pmid:9547107
Perri F et al. 13C-Octanoic acid breath test: valueless test for gastric emptying? 1998 Gastroenterology pmid:9547108
De Boeck K et al. Lipid digestion in cystic fibrosis: comparison of conventional and high-lipase enzyme therapy using the mixed-triglyceride breath test. 1998 J. Pediatr. Gastroenterol. Nutr. pmid:9552136
Sidossis LS et al. Regulation of fatty acid oxidation in untrained vs. trained men during exercise. 1998 Am. J. Physiol. pmid:9530135
Groves CE et al. Peritubular transport of ochratoxin A in rabbit renal proximal tubules. 1998 J. Pharmacol. Exp. Ther. pmid:9495853
Leverve X et al. Oxidative phosphorylation in intact hepatocytes: quantitative characterization of the mechanisms of change in efficiency and cellular consequences. 1998 Mol. Cell. Biochem. pmid:9746312
Decagny B et al. 1H-NMR on line monitoring of water activity during lipase catalysed esterification. 1998 Biochim. Biophys. Acta pmid:9748540
Kawashima H et al. Development of step-specific PET tracers for studying fatty acid beta-oxidation: biodistribution of [1-(11)C] octanoate analogs in rats and a cat. 1998 Nucl. Med. Biol. pmid:9751421
Nicolosi RJ et al. Effects of specific fatty acids (8:0, 14:0, cis-18:1, trans-18:1) on plasma lipoproteins, early atherogenic potential, and LDL oxidative properties in the hamster. 1998 J. Lipid Res. pmid:9788243
Yon JO et al. Incorporation of extracellular phospholipids and their effect on the growth and lipid metabolism of the Saccharomyces cerevisiae cho1/pss mutant. 1998 Biochim. Biophys. Acta pmid:9767089
Bonen A et al. Palmitate transport and fatty acid transporters in red and white muscles. 1998 Am. J. Physiol. pmid:9725814
Schommartz B et al. Significance of diagnostic parameters in [13C]octanoic acid gastric emptying breath tests. 1998 Isotopes Environ Health Stud pmid:9854848
Page M and Thorpe R IgG purification. 1998 Methods Mol. Biol. pmid:9664367
Page M and Thorpe R Purification of monoclonal antibodies. 1998 Methods Mol. Biol. pmid:9664368
Jones CD The genetic basis of Drosophila sechellia's resistance to a host plant toxin. 1998 Genetics pmid:9691045
Sibille B et al. 2,4 Dinitrophenol-uncoupling effect on delta psi in living hepatocytes depends on reducing-equivalent supply. 1998 Cytometry pmid:9627223
Yamamura N et al. Evaluation of [1-11C]octanoate as a new radiopharmaceutical for assessing liver function using positron emission tomography. 1998 Nucl. Med. Biol. pmid:9720664
Rothen SA et al. Biotransformation of octane by E. coli HB101[pGEc47] on defined medium: octanoate production and product inhibition. 1998 Biotechnol. Bioeng. pmid:10099269
Perri F et al. Patterns of symptoms in functional dyspepsia: role of Helicobacter pylori infection and delayed gastric emptying. 1998 Am. J. Gastroenterol. pmid:9820377
González A et al. [Applications of stable isotopes in biomedical sciences]. 1998 Apr-Jun Rev Med Univ Navarra pmid:10420942
González A et al. [Studying of gastric emptying for solids and liquids by means of using stable isotopes]. 1998 Apr-Jun Rev Med Univ Navarra pmid:10420944
Pailla K et al. TNF-alpha and IL-6 synergistically inhibit ketogenesis from fatty acids and alpha-ketoisocaproate in isolated rat hepatocytes. 1998 Sep-Oct JPEN J Parenter Enteral Nutr pmid:9739031
Bardi L et al. Saccharomyces cerevisiae cell fatty acid composition and release during fermentation without aeration and in absence of exogenous lipids. 1999 Int. J. Food Microbiol. pmid:10357281
Debreceni A et al. Capsaicin increases gastric emptying rate in healthy human subjects measured by 13C-labeled octanoic acid breath test. 1999 J. Physiol. Paris pmid:10674924
Cho W and Shen Z Efficient immobilization of phospholipase A2. 1999 Methods Mol. Biol. pmid:9918031
Tsuda M et al. Transport of ochratoxin A by renal multispecific organic anion transporter 1. 1999 J. Pharmacol. Exp. Ther. pmid:10336520
Otero R et al. A randomized blinded clinical trial of two antivenoms, prepared by caprylic acid or ammonium sulphate fractionation of IgG, in Bothrops and Porthidium snake bites in Colombia: correlation between safety and biochemical characteristics of antivenoms. 1999 Toxicon pmid:10340829
Barnett C et al. Reproducibility of the 13C-octanoic acid breath test for assessment of gastric emptying in healthy preterm infants. 1999 J. Pediatr. Gastroenterol. Nutr. pmid:10400099
Van Den Driessche M et al. Gastric emptying in formula-fed and breast-fed infants measured with the 13C-octanoic acid breath test. 1999 J. Pediatr. Gastroenterol. Nutr. pmid:10400103
Gao J and Serrero G Adipose differentiation related protein (ADRP) expressed in transfected COS-7 cells selectively stimulates long chain fatty acid uptake. 1999 J. Biol. Chem. pmid:10358026
Thumshirn M et al. Modulation of gastric sensory and motor functions by nitrergic and alpha2-adrenergic agents in humans. 1999 Gastroenterology pmid:10029616
Kemp-Harper R et al. Sodium ions in ordered environments in biological systems: analysis of 23Na NMR spectra. 1999 J. Magn. Reson. pmid:10497043
Robinson MK et al. A two-center study of the development of acute irritation responses to fatty acids. 1999 Am. J. Contact Dermatitis pmid:10444106
Zhang GG and Grant DJ Incorporation mechanism of guest molecules in crystals: solid solution or inclusion? 1999 Int J Pharm pmid:10370203
Matsuki H et al. Specific and non-specific binding of long-chain fatty acids to firefly luciferase: cutoff at octanoate. 1999 Biochim. Biophys. Acta pmid:9878713
Liu X et al. [One simple and efficient method for purification of IgG McAb from mice ascites: caprylic acid/ammonium sulfate precipitation]. 1999 Hua Xi Yi Ke Da Xue Xue Bao pmid:11387969
Toepfer M et al. Noninvasive (13)C-octanoic acid breath test shows delayed gastric emptying in patients with amyotrophic lateral sclerosis. 1999 Nov-Dec Digestion pmid:10545728
Ishii-Iwamoto EL et al. Effects of norepinephrine on the metabolism of fatty acids with different chain lengths in the perfused rat liver. 2000 Mol. Cell. Biochem. pmid:10821418
Cabrera-Crespo J et al. Albumin purification from human placenta. 2000 Biotechnol. Appl. Biochem. pmid:10744954
Vincent G et al. Citrate release by perfused rat hearts: a window on mitochondrial cataplerosis. 2000 Am. J. Physiol. Endocrinol. Metab. pmid:10780941
Watanabe K et al. Constitutive regulation of cardiac fatty acid metabolism through peroxisome proliferator-activated receptor alpha associated with age-dependent cardiac toxicity. 2000 J. Biol. Chem. pmid:10801788
Kuge Y et al. Preliminary evaluation of [1-11C]octanoate as a PET tracer for studying cerebral ischemia: a PET study in rat and canine models of focal cerebral ischemia. 2000 Ann Nucl Med pmid:10770584
Panchal AR et al. Partitioning of pyruvate between oxidation and anaplerosis in swine hearts. 2000 Am. J. Physiol. Heart Circ. Physiol. pmid:11045976
Lee JS et al. Toward office-based measurement of gastric emptying in symptomatic diabetics using [13C]octanoic acid breath test. 2000 Am. J. Gastroenterol. pmid:11051344
Kim JY et al. Lipid oxidation is reduced in obese human skeletal muscle. 2000 Am. J. Physiol. Endocrinol. Metab. pmid:11052958
Awan MM et al. Mechanisms whereby glucose deprivation triggers metabolic preconditioning in the isolated rat heart. 2000 Mol. Cell. Biochem. pmid:11055554
Schwarzmann G et al. Using biotinylated gangliosides to study their distribution and traffic in cells by immunoelectron microscopy. 2000 Meth. Enzymol. pmid:11070901
Barron JT et al. Effect of serum albumin on vascular smooth muscle metabolism. 2000 Biochim. Biophys. Acta pmid:10924897
Durner R et al. Accumulation of Poly[(R)-3-hydroxyalkanoates] in Pseudomonas oleovorans during growth with octanoate in continuous culture at different dilution rates. 2000 Appl. Environ. Microbiol. pmid:10919799
Mu H and Høy CE Effects of different medium-chain fatty acids on intestinal absorption of structured triacylglycerols. 2000 Lipids pmid:10695928
Tian W et al. Production of polyesters consisting of medium chain length 3-hydroxyalkanoic acids by Pseudomonas mendocina 0806 from various carbon sources. 2000 Antonie Van Leeuwenhoek pmid:10696875
Hajjaj H et al. Medium-chain fatty acids affect citrinin production in the filamentous fungus Monascus ruber. 2000 Appl. Environ. Microbiol. pmid:10698780
Hacking MA et al. Lipase and esterase-catalyzed acylation of hetero-substituted nitrogen nucleophiles in water and organic solvents. 2000 Biotechnol. Bioeng. pmid:10699875
Boullanger P et al. Syntheses of amphiphilic glycosylamides from glycosyl azides without transient reduction to glycosylamines. 2000 Carbohydr. Res. pmid:10702876
Iwahashi H Some polyphenols inhibit the formation of pentyl radical and octanoic acid radical in the reaction mixture of linoleic acid hydroperoxide with ferrous ions. 2000 Biochem. J. pmid:10677343
Shen JJ et al. Acylcarnitines in fibroblasts of patients with long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency and other fatty acid oxidation disorders. 2000 J. Inherit. Metab. Dis. pmid:10682306
Saad A and Sayed N Discriminant analysis of free fatty acids of some Egyptian snails as a step for schistosomiasis control: new trends. 2000 J Egypt Public Health Assoc pmid:17219851
Gandhi NN and Mukherjee KD Papaya (Carica papaya) lipase with some distinct acyl and alkyl specificities as compared with microbial lipases. 2000 Biochem. Soc. Trans. pmid:11171278
Hoffmann N et al. Homologous functional expression of cryptic phaG from Pseudomonas oleovorans establishes the transacylase-mediated polyhydroxyalkanoate biosynthetic pathway. 2000 Appl. Microbiol. Biotechnol. pmid:11131392
Wiberg E et al. The distribution of caprylate, caprate and laurate in lipids from developing and mature seeds of transgenic Brassica napus L. 2000 Planta pmid:11219581
Hosoda H et al. Ghrelin and des-acyl ghrelin: two major forms of rat ghrelin peptide in gastrointestinal tissue. 2000 Biochem. Biophys. Res. Commun. pmid:11162448