| MeSH term | MeSH ID | Detail |
|---|---|---|
| Amyotrophic Lateral Sclerosis | D000690 | 11 associated lipids |
| Asthenia | D001247 | 5 associated lipids |
| Cholestasis, Extrahepatic | D001651 | 7 associated lipids |
| Biliary Fistula | D001658 | 13 associated lipids |
| Blind Loop Syndrome | D001765 | 3 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Campylobacter Infections | D002169 | 13 associated lipids |
| Brain Ischemia | D002545 | 89 associated lipids |
| Ischemic Attack, Transient | D002546 | 42 associated lipids |
| Chest Pain | D002637 | 4 associated lipids |
octanoic acid
octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.
Cross Reference
Introduction
To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with octanoic acid?
octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with octanoic acid
PubChem Associated disorders and diseases
What pathways are associated with octanoic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with octanoic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with octanoic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with octanoic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with octanoic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with octanoic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with octanoic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Rosario P and Medina JM | Effect of gluconeogenic substrates on ketogenesis in isolated rat hepatocytes. I. Effect of glycerol. | 1980 | Rev. Esp. Fisiol. | pmid:7221165 |
| Carrington MJ et al. | Octanoate and palmitate as substrates for ketogenesis by hepatocytes isolated from suckling rabbits. | 1981 | Biochem. Soc. Trans. | pmid:7215663 |
| Seydoux J et al. | Functional disconnection of brown adipose tissue in hypothalamic obesity in rats. | 1981 | Pflugers Arch. | pmid:7195549 |
| Weight MJ et al. | Cholesterol-ascorbic acid interactions in guinea pig liver homogenates, and in the in situ perfused liver: relationship between ascorbic acid status and cholesterol and bile acid synthesis from mevalonate. | 1982 | Int J Vitam Nutr Res | pmid:7174228 |
| Shipp DA et al. | Development of fatty acid oxidation in neonatal guinea-pig liver. | 1982 | Biochem. J. | pmid:7165728 |
| Reuge C | [Enzymatic determination of caprylates in protein preparations]. | 1982 | Rev. Fr. Transfus. Immunohematol. | pmid:7163732 |
| Roeder LM et al. | The effects of ketone bodies, bicarbonate, and calcium on hepatic mitochondrial ketogenesis. | 1982 | Arch. Biochem. Biophys. | pmid:7138017 |
| Ebbesen F and Brodersen R | Comparison between two preparations of human serum albumin in treatment of neonatal hyperbilirubinaemia. | 1982 | Acta Paediatr Scand | pmid:7136621 |
| Sugano T et al. | Stimulation of gluconeogenesis by glucagon and norepinephrine in the perfused chicken liver. | 1982 | J. Biochem. | pmid:7118865 |
| Sugano T et al. | Intracellular redox state and control of gluconeogenesis in perfused chicken liver. | 1982 | J. Biochem. | pmid:7118853 |
| Zeneroli ML et al. | Visual evoked potentials in encephalopathy induced by galactosamine, ammonia, dimethyldisulfide, and octanoic acid. | 1982 Sep-Oct | Hepatology | pmid:7118066 |
| Garcia-Esteller SC et al. | Role of the state of reduction of the NAD system on the regulation of hepatic protein synthesis in the rat in vivo. | 1982 | Int. J. Biochem. | pmid:7106360 |
| Odessey R and Chace KV | Utilization of endogenous lipid, glycogen, and protein by rabbit aorta. | 1982 | Am. J. Physiol. | pmid:7091374 |
| Haidukewych D et al. | Monitoring octanoic and decanoic acids in plasma from children with intractable epilepsy treated with medium-chain triglyceride diet. | 1982 | Clin. Chem. | pmid:7074833 |
| Zwiebel FM et al. | Role of pyruvate transporter in the regulation of the pyruvate dehydrogenase multienzyme complex in perfused rat liver. | 1982 | Biochemistry | pmid:7074018 |
| Borg LA | Effects of octanoate and ketone and bodies on the structure and function of isolated pancreatic islets in tissue culture. | 1981 | Acta Endocrinol. | pmid:7010865 |
| Barth CA et al. | Morphology and metabolism of adult rat hepatocytes in primary culture. | 1980 | Hoppe-Seyler's Z. Physiol. Chem. | pmid:6997170 |
| Caffier G et al. | Contractile properties of isolated frog skeletal muscles under the influence of Na-octanoate. | 1982 | Acta Biol. Med. Ger. | pmid:6981273 |
| Caffier G and Küchler G | [Effect of homologous n-alkanoic acids on the function of isolated skeletal muscles. IV. Effect of Na-octanoate on action potentials]. | 1980 | Acta Biol. Med. Ger. | pmid:6969509 |
| Kössler F et al. | Octanol and octanoate induced inhibition of the mechanical activity of isolated frog skeletal muscles. | 1980 | Chem. Biol. Interact. | pmid:6967777 |
| Caffier G et al. | The influence of free fatty acids on functional properties of isolated skeletal muscles. Octanoate action on membrane resistance. | 1980 | Pflugers Arch. | pmid:6966791 |
| Bagnasco SM et al. | The regulation of renal ammoniagenesis in the rat by extracellular factors. III. Effects of various fuels on in vitro ammoniagenesis. | 1983 | Metab. Clin. Exp. | pmid:6888270 |
| Bünger R et al. | Energy utilization and pyruvate as determinants of pyruvate dehydrogenase in norepinephrine-stimulated heart. | 1983 | Pflugers Arch. | pmid:6878010 |
| Rabinowitz JL et al. | Lipid composition and de novo lipid biosynthesis of human palmar fat in Dupuytren's disease. | 1983 | Lipids | pmid:6877040 |
| Shimizu H | [Comparative studies on perfused adult and fetal guinea pig liver metabolism before and after anoxia loadings, with special reference to intracellular redox state]. | 1983 | Nippon Sanka Fujinka Gakkai Zasshi | pmid:6875338 |
| Shapiro IM et al. | Studies of nucleotides of growth-plate cartilage: evidence linking changes in cellular metabolism with cartilage calcification. | 1983 | Biosci. Rep. | pmid:6871381 |
| Pégorier JP et al. | Metabolic fate of non-esterified fatty acids in isolated hepatocytes from newborn and young pigs. Evidence for a limited capacity for oxidation and increased capacity for esterification. | 1983 | Biochem. J. | pmid:6870859 |
| Hjelmeland LM et al. | A new class of nonionic detergents with a gluconamide polar group. | 1983 | Anal. Biochem. | pmid:6869837 |
| Werner JC et al. | Fatty acid and glucose utilization in isolated, working fetal pig hearts. | 1983 | Am. J. Physiol. | pmid:6869527 |
| Rhead WJ et al. | Dicarboxylic aciduria: deficient [1-14C]octanoate oxidation and medium-chain acyl-CoA dehydrogenase in fibroblasts. | 1983 | Science | pmid:6857268 |
| Bell FP | Effect of the plasticizer di(2-ethylhexyl) adipate (dioctyladipate, DOA) on lipid metabolism in the rat: I. Inhibition of cholesterolgenesis and modification of phospholipid synthesis. | 1983 | Lipids | pmid:6855481 |
| Mayorek N and Bar-Tana J | Medium chain fatty acids as specific substrates for diglyceride acyltransferase in cultured hepatocytes. | 1983 | J. Biol. Chem. | pmid:6853505 |
| Latipää PM et al. | Regulation of fatty acid oxidation in heart muscle. Effects of pyruvate and dichloroacetate. | 1983 | Biochim. Biophys. Acta | pmid:6849964 |
| Werner JC et al. | Fatty acid and glucose utilization in isolated, working newborn pig hearts. | 1983 | Am. J. Physiol. | pmid:6849379 |
| Almås I et al. | The action of vasopressin and calcium on palmitate metabolism in hepatocytes and isolated mitochondria from rat liver. | 1983 | Arch. Biochem. Biophys. | pmid:6847192 |
| Zabłocki K et al. | The inhibitory effect of octanoate, palmitate and oleate on glucose formation in rabbit kidney tubules. | 1983 | Biochim. Biophys. Acta | pmid:6838901 |
| Stange EF and Dietschy JM | Absolute rates of cholesterol synthesis in rat intestine in vitro and in vivo: a comparison of different substrates in slices and isolated cells. | 1983 | J. Lipid Res. | pmid:6833883 |
| Windus-Podehl G et al. | Encephalopathic effect of phenol in rats. | 1983 | J. Lab. Clin. Med. | pmid:6833829 |
| Ledden DJ et al. | Characterization of fragments of human albumin purified by Cibacron blue F3GA affinity chromatography. | 1982 | Biochem. J. | pmid:6814424 |
| Buchowicz I et al. | Anti-pseudomonas immunoglobulin. II. Preparation of purified sheep immunoglobulins. | 1981 | Arch. Immunol. Ther. Exp. (Warsz.) | pmid:6812541 |
| Palabost-Charles L | Selection at the alpha-Gpdh locus in experimental populations of Drosophila melanogaster. | 1982 | Biochem. Genet. | pmid:6810873 |
| Abbott FS et al. | Valproic acid analysis in saliva and serum using selected ion monitoring (electron ionization) of the tert.-butyldimethylsilyl derivatives. | 1982 | J. Chromatogr. | pmid:6801067 |
| Derr RF and Zieve L | Effect of fatty acids on the disposition of ammonia. | 1976 | J. Pharmacol. Exp. Ther. | pmid:6789 |
| Bijlsma R | Polymorphism at the G6pd and 6Pgd loci in Drosophila melanogaster. IV. Genetic factors modifying enzyme activity. | 1980 | Biochem. Genet. | pmid:6781470 |
| Chan SC | Monitoring serum valproic acid by gas chromatography with electron-capture detection. | 1980 | Clin. Chem. | pmid:6774836 |
| ChacÃn J et al. | Role of fatty acid oxidation in mechanism of action of gastric secretagogues. | 1980 | Am. J. Physiol. | pmid:6768310 |
| White RH | Stable isotope studies on the biosynthesis of lipoic acid in Escherichia coli. | 1980 | Biochemistry | pmid:6766313 |
| Elliott JR et al. | The asymmetrical effects of some ionized n-octyl derivatives on the sodium current of the giant axon of Loligo forbesi. | 1984 | J. Physiol. (Lond.) | pmid:6747855 |
| Abumrad NA et al. | Permeation of long-chain fatty acid into adipocytes. Kinetics, specificity, and evidence for involvement of a membrane protein. | 1984 | J. Biol. Chem. | pmid:6746632 |
| Soboll S et al. | Effect of long-chain fatty acyl-CoA on mitochondrial and cytosolic ATP/ADP ratios in the intact liver cell. | 1984 | Biochem. J. | pmid:6743276 |
| Shrake A et al. | Thermal stability of human albumin measured by differential scanning calorimetry. I. Effects of caprylate and N-acetyltryptophanate. | 1984 | Vox Sang. | pmid:6741034 |
| Yu MW and Finlayson JS | Stabilization of human albumin by caprylate and acetyltryptophanate. | 1984 | Vox Sang. | pmid:6741030 |
| Ross PD et al. | Thermal stability of human albumin measured by differential scanning calorimetry. II. Effects of isomers of N-acetyltryptophanate and tryptophanate, pH, reheating, and dimerization. | 1984 | Vox Sang. | pmid:6741029 |
| Chen V et al. | Regulation of substrate oxidation in isolated myocardial cells by beta-hydroxybutyrate. | 1984 | Horm. Metab. Res. | pmid:6735347 |
| Aurousseau B et al. | [Effect of the replacement of a part of the tallow in a milk supply with tricaprylin or coconut oil on the use of energy and nitrogen by the preruminant calf]. | 1984 | Reprod Nutr Dev | pmid:6729239 |
| Soboll S et al. | Influence of fatty acids on energy metabolism. 2. Kinetics of changes in metabolic rates and changes in subcellular adenine nucleotide contents and pH gradients following addition of octanoate and oleate in perfused rat liver. | 1984 | Eur. J. Biochem. | pmid:6723661 |
| Reed WD et al. | A double-isotope method for the measurement of ketone-body turnover in the rat. Effect of L-alanine. | 1984 | Biochem. J. | pmid:6721850 |
| Habeeb AF and Francis RD | Preparation of human immunoglobulin by caprylic acid precipitation. | 1984 | Prep. Biochem. | pmid:6718324 |
| Otto DA | Relationship of the ATP/ADP ratio to the site of octanoate activation. | 1984 | J. Biol. Chem. | pmid:6715356 |
| Thayer WS | Inhibition of mitochondrial fatty acid oxidation in pentenoic acid-induced fatty liver. A possible model for Reye's syndrome. | 1984 | Biochem. Pharmacol. | pmid:6712730 |
| Nauclér J et al. | Evaluation of kidney viability during hypothermic perfusion or cold storage. | 1984 | Eur Surg Res | pmid:6698069 |
| Bell FP | Di(2-ethylhexyl)adipate (DEHA): effect on plasma lipids and hepatic cholesterolgenesis in the rat. | 1984 | Bull Environ Contam Toxicol | pmid:6697017 |
| Kohlwein SD and Paltauf F | Uptake of fatty acids by the yeasts, Saccharomyces uvarum and Saccharomycopsis lipolytica. | 1984 | Biochim. Biophys. Acta | pmid:6696936 |
| Yu MW and Finlayson JS | Quantitative determination of the stabilizers octanoic acid and N-acetyl-DL-tryptophan in human albumin products. | 1984 | J Pharm Sci | pmid:6694090 |
| Pappas SC et al. | Visual evoked potentials in a rabbit model of hepatic encephalopathy. II. Comparison of hyperammonemic encephalopathy, postictal coma, and coma induced by synergistic neurotoxins. | 1984 | Gastroenterology | pmid:6693016 |
| Parker WD et al. | Effects of octanoate on rat brain and liver mitochondria. | 1983 | Neurology | pmid:6684238 |
| Bauché F et al. | Inhibition in vitro of acyl-CoA dehydrogenases by 2-mercaptoacetate in rat liver mitochondria. | 1983 | Biochem. J. | pmid:6661181 |
| Russo C et al. | Re.: Purification of IgG monoclonal antibody by caprylic acid precipitation. | 1983 | J. Immunol. Methods | pmid:6655243 |
| Deaciuc IV et al. | Studies on the mechanism of action of the hypoglycemic agent, 2-(3-methylcinnamylhydrazono)-propionate (BM 42.304). | 1983 | Biochem. Pharmacol. | pmid:6651864 |
| Tangerman A et al. | Quantitative determination of C2-C8 volatile fatty acids in human serum by vacuum distillation and gas chromatography. | 1983 | Clin. Chim. Acta | pmid:6627690 |
| Ferré P et al. | Development and regulation of ketogenesis in hepatocytes isolated from newborn rats. | 1983 | Biochem. J. | pmid:6626164 |
| Bryła J and Niedzwiecka A | The stimulatory effect of oleate on citrulline formation from carbamoyl phosphate and ornithine in rat-liver mitochondria: the relation to ornithine uptake. | 1983 | Int. J. Biochem. | pmid:6617963 |
| Spydevold O and Hokland B | Release of leucine and isoleucine metabolites by perfused skeletal muscle and liver of rat. | 1983 | Int. J. Biochem. | pmid:6617955 |
| Abidova SS and Ovchinnikov IV | [Effect of novodrin on fatty acid oxidation by the myocardial mitochondria of white rats]. | 1983 Jul-Aug | Farmakol Toksikol | pmid:6617836 |
| MartÃnez Izquierdo JA et al. | Fatty acid-glucose interaction in the control of protein synthesis by isolated rat lung cells. | 1983 | Biochim. Biophys. Acta | pmid:6615881 |
| Lagercrantz C and Larsson T | Comparative studies of the binding of some ligands to human serum albumin non-covalently attached to immobilized Cibacron Blue, or covalently immobilized on Sepharose, by column affinity chromatography. | 1983 | Biochem. J. | pmid:6615442 |
| Silavin SL et al. | Reevaluation of the effects of cytochalasins on steroidogenesis: studies on hamster granulosa cells. | 1984 | Endocrinology | pmid:6592092 |
| Pösö AR and Mortimore GE | Requirement for alanine in the amino acid control of deprivation-induced protein degradation in liver. | 1984 | Proc. Natl. Acad. Sci. U.S.A. | pmid:6589593 |
| Scholz R et al. | The effect of fatty acids on the regulation of pyruvate dehydrogenase in perfused rat liver. | 1978 | Eur. J. Biochem. | pmid:658055 |
| Herold G et al. | Cholesterol synthesis and esterification in cultured intestinal mucosa. Evidence for compartmentation. | 1984 | Biochim. Biophys. Acta | pmid:6567470 |
| Mannaerts GP et al. | Hepatic fatty acid oxidation and ketogenesis after clofibrate treatment. | 1978 | Biochim. Biophys. Acta | pmid:656451 |
| Allen PC and Danforth HD | The effects of Eimeria acervulina infection on the metabolism of chick duodenal tissue. | 1984 | Vet. Parasitol. | pmid:6538718 |
| Schönfeld P et al. | Influence of octanoate on the rate of oxidative phosphorylation and the associated extramitochondrial ATP/ADP ratios studied with isolated rat liver mitochondria oxidizing pyruvate. | 1984 | Biomed. Biochim. Acta | pmid:6525184 |
| Wagenmakers AJ et al. | Increase of the activity state and loss of total activity of the branched-chain 2-oxo acid dehydrogenase in rat diaphragm during incubation. | 1984 | Biochem. J. | pmid:6517861 |
| Riecken EO | [Structural and functional findings in experimental blind loop syndrome]. | 1984 | Nahrung | pmid:6493325 |
| Zieve L et al. | Brain methanethiol and ammonia concentrations in experimental hepatic coma and coma induced by injections of various combinations of these substances. | 1984 | J. Lab. Clin. Med. | pmid:6491466 |
| Sundqvist KE et al. | Effect of acetate and octanoate on tricarboxylic acid cycle metabolite disposal during propionate oxidation in the perfused rat heart. | 1984 | Biochim. Biophys. Acta | pmid:6487652 |
| Kim CS et al. | L-carnitine: therapeutic strategy for metabolic encephalopathy. | 1984 | Brain Res. | pmid:6478235 |
| Buxton DB et al. | Regulatory effects of fatty acids on decarboxylation of leucine and 4-methyl-2-oxopentanoate in the perfused rat heart. | 1984 | Biochem. J. | pmid:6477487 |
| Felix R and Fleisch H | Increase in fatty acid oxidation in calvaria cells cultured with diphosphonates. | 1981 | Biochem. J. | pmid:6458286 |
| Allen PC | Physiological responses of chicken gut tissue to infection with Eimeria acervulina. | 1984 Oct-Dec | Avian Dis. | pmid:6441557 |
| Schudt C and Simon A | Effects of sodium 2-[5-(4-chlorophenyl)pentyl]-oxirane-2-carboxylate (POCA) on carbohydrate and fatty acid metabolism in liver and muscle. | 1984 | Biochem. Pharmacol. | pmid:6437406 |
| Duran M et al. | The differential diagnosis of dicarboxylic aciduria. | 1984 | J. Inherit. Metab. Dis. | pmid:6434845 |
| Blumenthal SA | Inhibition of gluconeogenesis in rat liver by lipoic acid. Evidence for more than one site of action. | 1984 | Biochem. J. | pmid:6430273 |
| Meisner H and Neet K | Competitive binding of long-chain free fatty acids, octanoate, and chlorophenoxyisobutyrate to albumin. | 1978 | Mol. Pharmacol. | pmid:642932 |
| Scholz R et al. | Influence of fatty acids on energy metabolism. 1. Stimulation of oxygen consumption, ketogenesis and CO2 production following addition of octanoate and oleate in perfused rat liver. | 1984 | Eur. J. Biochem. | pmid:6426957 |
| Hampson RK et al. | Regulation of the glycine cleavage system in the isolated perfused rat liver. | 1984 | J. Biol. Chem. | pmid:6420402 |
| Nagi MN et al. | Biochemical properties of short- and long-chain rat liver microsomal trans-2-enoyl coenzyme A reductase. | 1983 | Arch. Biochem. Biophys. | pmid:6416174 |
| McDonough KH and Spitzer JJ | Effects of hypoxia and reoxygenation on adult rat heart cell metabolism. | 1983 | Proc. Soc. Exp. Biol. Med. | pmid:6412237 |
| Becker CM and Harris RA | Influence of valproic acid on hepatic carbohydrate and lipid metabolism. | 1983 | Arch. Biochem. Biophys. | pmid:6407400 |