| MeSH term | MeSH ID | Detail |
|---|---|---|
| Amyotrophic Lateral Sclerosis | D000690 | 11 associated lipids |
| Asthenia | D001247 | 5 associated lipids |
| Cholestasis, Extrahepatic | D001651 | 7 associated lipids |
| Biliary Fistula | D001658 | 13 associated lipids |
| Blind Loop Syndrome | D001765 | 3 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Campylobacter Infections | D002169 | 13 associated lipids |
| Brain Ischemia | D002545 | 89 associated lipids |
| Ischemic Attack, Transient | D002546 | 42 associated lipids |
| Chest Pain | D002637 | 4 associated lipids |
| Chickenpox | D002644 | 1 associated lipids |
| Chronic Disease | D002908 | 7 associated lipids |
| Chylothorax | D002916 | 1 associated lipids |
| Coccidiosis | D003048 | 3 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Crohn Disease | D003424 | 12 associated lipids |
| Cystic Fibrosis | D003550 | 65 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Diabetes Mellitus, Experimental | D003921 | 85 associated lipids |
| Diabetes Mellitus, Type 1 | D003922 | 56 associated lipids |
octanoic acid
octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.
Cross Reference
Introduction
To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with octanoic acid?
octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with octanoic acid
PubChem Associated disorders and diseases
What pathways are associated with octanoic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with octanoic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with octanoic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with octanoic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with octanoic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with octanoic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with octanoic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Vinay P et al. | Effect of fatty acids on renal ammoniagenesis in in vivo and in vitro studies. | 1976 | Am. J. Physiol. | pmid:970471 |
| Barbee RW et al. | T3 treatment does not prevent myocardial dysfunction in chronically diabetic rats. | 1988 | Am. J. Physiol. | pmid:2830793 |
| McDaniel HG | Acute suppression of hepatic gluconeogenesis by glucose in the intact animal. | 1975 | Am. J. Physiol. | pmid:1211489 |
| Burns AH and Reddy WJ | Amino acid stimulation of oxygen and substrate utilization by cardiac myocytes. | 1978 | Am. J. Physiol. | pmid:727249 |
| REES ED and KLINE DL | Metabolism of octanoate by fatty liver slices. | 1957 | Am. J. Physiol. | pmid:13470069 |
| Coyle EF et al. | Fatty acid oxidation is directly regulated by carbohydrate metabolism during exercise. | 1997 | Am. J. Physiol. | pmid:9277379 |
| Beaufrere B et al. | Apparent decreased oxidation and turnover of leucine during infusion of medium-chain triglycerides. | 1985 | Am. J. Physiol. | pmid:3895976 |
| Barron JT et al. | Substrate-dependent alteration in O2 consumption and energy metabolism in vascular smooth muscle. | 1996 | Am. J. Physiol. | pmid:8764234 |
| Bonen A et al. | Palmitate transport and fatty acid transporters in red and white muscles. | 1998 | Am. J. Physiol. | pmid:9725814 |
| Hütter JF et al. | Effect of fatty acid oxidation on efficiency of energy production in rat heart. | 1985 | Am. J. Physiol. | pmid:4051011 |
| Azain MJ and Ontko JA | An explanation for decreased ketogenesis in the liver of the obese Zucker rat. | 1989 | Am. J. Physiol. | pmid:2552844 |
| Witters LA and Trasko CS | Regulation of hepatic free fatty acid metabolism by glucagon and insulin. | 1979 | Am. J. Physiol. | pmid:157075 |
| Bielefeld DR et al. | Altered sensitivity of chronic diabetic rat heart to calcium. | 1983 | Am. J. Physiol. | pmid:6362427 |
| Trimble ME | Transport and metabolism of octanoate by the perfused rat kidney. | 1979 | Am. J. Physiol. | pmid:474762 |
| Odessey R and Chace KV | Utilization of endogenous lipid, glycogen, and protein by rabbit aorta. | 1982 | Am. J. Physiol. | pmid:7091374 |
| Cha BS et al. | Impaired fatty acid metabolism in type 2 diabetic skeletal muscle cells is reversed by PPARgamma agonists. | 2005 | Am. J. Physiol. Endocrinol. Metab. | pmid:15727952 |
| Tham E et al. | Acylated ghrelin concentrations are markedly decreased during pregnancy in mothers with and without gestational diabetes: relationship with cholinesterase. | 2009 | Am. J. Physiol. Endocrinol. Metab. | pmid:19240252 |
| Hommelberg PP et al. | Fatty acid-induced NF-kappaB activation and insulin resistance in skeletal muscle are chain length dependent. | 2009 | Am. J. Physiol. Endocrinol. Metab. | pmid:18957619 |
| Bando M et al. | Transgenic overexpression of intraislet ghrelin does not affect insulin secretion or glucose metabolism in vivo. | 2012 | Am. J. Physiol. Endocrinol. Metab. | pmid:22114024 |
| Turcotte LP et al. | High carbohydrate availability increases LCFA uptake and decreases LCFA oxidation in perfused muscle. | 2002 | Am. J. Physiol. Endocrinol. Metab. | pmid:11739099 |