octanoic acid

octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.

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Introduction

To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with octanoic acid?

octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with octanoic acid

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Diarrhea D003967 32 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Stomach Diseases D013272 7 associated lipids
Inflammation D007249 119 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Body Weight D001835 333 associated lipids
Edema D004487 152 associated lipids
Hepatic Encephalopathy D006501 9 associated lipids
Liver Cirrhosis, Experimental D008106 36 associated lipids
Hypothyroidism D007037 32 associated lipids
Kidney Diseases D007674 29 associated lipids
Glioma D005910 112 associated lipids
Metabolism, Inborn Errors D008661 46 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Obesity D009765 29 associated lipids
Hemorrhage D006470 15 associated lipids
Malocclusion D008310 3 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with octanoic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with octanoic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with octanoic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with octanoic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with octanoic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with octanoic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with octanoic acid

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Authors Title Published Journal PubMed Link
Rosario P and Medina JM Effect of gluconeogenic substrates on ketogenesis in isolated rat hepatocytes. I. Effect of glycerol. 1980 Rev. Esp. Fisiol. pmid:7221165
Carrington MJ et al. Octanoate and palmitate as substrates for ketogenesis by hepatocytes isolated from suckling rabbits. 1981 Biochem. Soc. Trans. pmid:7215663
Seydoux J et al. Functional disconnection of brown adipose tissue in hypothalamic obesity in rats. 1981 Pflugers Arch. pmid:7195549
Weight MJ et al. Cholesterol-ascorbic acid interactions in guinea pig liver homogenates, and in the in situ perfused liver: relationship between ascorbic acid status and cholesterol and bile acid synthesis from mevalonate. 1982 Int J Vitam Nutr Res pmid:7174228
Shipp DA et al. Development of fatty acid oxidation in neonatal guinea-pig liver. 1982 Biochem. J. pmid:7165728
Reuge C [Enzymatic determination of caprylates in protein preparations]. 1982 Rev. Fr. Transfus. Immunohematol. pmid:7163732
Roeder LM et al. The effects of ketone bodies, bicarbonate, and calcium on hepatic mitochondrial ketogenesis. 1982 Arch. Biochem. Biophys. pmid:7138017
Ebbesen F and Brodersen R Comparison between two preparations of human serum albumin in treatment of neonatal hyperbilirubinaemia. 1982 Acta Paediatr Scand pmid:7136621
Sugano T et al. Stimulation of gluconeogenesis by glucagon and norepinephrine in the perfused chicken liver. 1982 J. Biochem. pmid:7118865
Sugano T et al. Intracellular redox state and control of gluconeogenesis in perfused chicken liver. 1982 J. Biochem. pmid:7118853
Zeneroli ML et al. Visual evoked potentials in encephalopathy induced by galactosamine, ammonia, dimethyldisulfide, and octanoic acid. 1982 Sep-Oct Hepatology pmid:7118066
Garcia-Esteller SC et al. Role of the state of reduction of the NAD system on the regulation of hepatic protein synthesis in the rat in vivo. 1982 Int. J. Biochem. pmid:7106360
Odessey R and Chace KV Utilization of endogenous lipid, glycogen, and protein by rabbit aorta. 1982 Am. J. Physiol. pmid:7091374
Haidukewych D et al. Monitoring octanoic and decanoic acids in plasma from children with intractable epilepsy treated with medium-chain triglyceride diet. 1982 Clin. Chem. pmid:7074833
Zwiebel FM et al. Role of pyruvate transporter in the regulation of the pyruvate dehydrogenase multienzyme complex in perfused rat liver. 1982 Biochemistry pmid:7074018
Borg LA Effects of octanoate and ketone and bodies on the structure and function of isolated pancreatic islets in tissue culture. 1981 Acta Endocrinol. pmid:7010865
Barth CA et al. Morphology and metabolism of adult rat hepatocytes in primary culture. 1980 Hoppe-Seyler's Z. Physiol. Chem. pmid:6997170
Caffier G et al. Contractile properties of isolated frog skeletal muscles under the influence of Na-octanoate. 1982 Acta Biol. Med. Ger. pmid:6981273
Caffier G and Küchler G [Effect of homologous n-alkanoic acids on the function of isolated skeletal muscles. IV. Effect of Na-octanoate on action potentials]. 1980 Acta Biol. Med. Ger. pmid:6969509
Kössler F et al. Octanol and octanoate induced inhibition of the mechanical activity of isolated frog skeletal muscles. 1980 Chem. Biol. Interact. pmid:6967777