octanoic acid

octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.

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Introduction

To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with octanoic acid?

octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with octanoic acid

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Diarrhea D003967 32 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Stomach Diseases D013272 7 associated lipids
Inflammation D007249 119 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Body Weight D001835 333 associated lipids
Edema D004487 152 associated lipids
Hepatic Encephalopathy D006501 9 associated lipids
Liver Cirrhosis, Experimental D008106 36 associated lipids
Hypothyroidism D007037 32 associated lipids
Kidney Diseases D007674 29 associated lipids
Glioma D005910 112 associated lipids
Metabolism, Inborn Errors D008661 46 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Obesity D009765 29 associated lipids
Hemorrhage D006470 15 associated lipids
Malocclusion D008310 3 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with octanoic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with octanoic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with octanoic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with octanoic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with octanoic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with octanoic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with octanoic acid

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Authors Title Published Journal PubMed Link
Caffier G et al. The influence of free fatty acids on functional properties of isolated skeletal muscles. Octanoate action on membrane resistance. 1980 Pflugers Arch. pmid:6966791
Bagnasco SM et al. The regulation of renal ammoniagenesis in the rat by extracellular factors. III. Effects of various fuels on in vitro ammoniagenesis. 1983 Metab. Clin. Exp. pmid:6888270
Bünger R et al. Energy utilization and pyruvate as determinants of pyruvate dehydrogenase in norepinephrine-stimulated heart. 1983 Pflugers Arch. pmid:6878010
Rabinowitz JL et al. Lipid composition and de novo lipid biosynthesis of human palmar fat in Dupuytren's disease. 1983 Lipids pmid:6877040
Shimizu H [Comparative studies on perfused adult and fetal guinea pig liver metabolism before and after anoxia loadings, with special reference to intracellular redox state]. 1983 Nippon Sanka Fujinka Gakkai Zasshi pmid:6875338
Shapiro IM et al. Studies of nucleotides of growth-plate cartilage: evidence linking changes in cellular metabolism with cartilage calcification. 1983 Biosci. Rep. pmid:6871381
Pégorier JP et al. Metabolic fate of non-esterified fatty acids in isolated hepatocytes from newborn and young pigs. Evidence for a limited capacity for oxidation and increased capacity for esterification. 1983 Biochem. J. pmid:6870859
Hjelmeland LM et al. A new class of nonionic detergents with a gluconamide polar group. 1983 Anal. Biochem. pmid:6869837
Werner JC et al. Fatty acid and glucose utilization in isolated, working fetal pig hearts. 1983 Am. J. Physiol. pmid:6869527
Rhead WJ et al. Dicarboxylic aciduria: deficient [1-14C]octanoate oxidation and medium-chain acyl-CoA dehydrogenase in fibroblasts. 1983 Science pmid:6857268
Bell FP Effect of the plasticizer di(2-ethylhexyl) adipate (dioctyladipate, DOA) on lipid metabolism in the rat: I. Inhibition of cholesterolgenesis and modification of phospholipid synthesis. 1983 Lipids pmid:6855481
Mayorek N and Bar-Tana J Medium chain fatty acids as specific substrates for diglyceride acyltransferase in cultured hepatocytes. 1983 J. Biol. Chem. pmid:6853505
Latipää PM et al. Regulation of fatty acid oxidation in heart muscle. Effects of pyruvate and dichloroacetate. 1983 Biochim. Biophys. Acta pmid:6849964
Werner JC et al. Fatty acid and glucose utilization in isolated, working newborn pig hearts. 1983 Am. J. Physiol. pmid:6849379
Almås I et al. The action of vasopressin and calcium on palmitate metabolism in hepatocytes and isolated mitochondria from rat liver. 1983 Arch. Biochem. Biophys. pmid:6847192
Zabłocki K et al. The inhibitory effect of octanoate, palmitate and oleate on glucose formation in rabbit kidney tubules. 1983 Biochim. Biophys. Acta pmid:6838901
Stange EF and Dietschy JM Absolute rates of cholesterol synthesis in rat intestine in vitro and in vivo: a comparison of different substrates in slices and isolated cells. 1983 J. Lipid Res. pmid:6833883
Windus-Podehl G et al. Encephalopathic effect of phenol in rats. 1983 J. Lab. Clin. Med. pmid:6833829
Ledden DJ et al. Characterization of fragments of human albumin purified by Cibacron blue F3GA affinity chromatography. 1982 Biochem. J. pmid:6814424
Buchowicz I et al. Anti-pseudomonas immunoglobulin. II. Preparation of purified sheep immunoglobulins. 1981 Arch. Immunol. Ther. Exp. (Warsz.) pmid:6812541