octanoic acid

octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.

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Introduction

To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with octanoic acid?

octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with octanoic acid

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Diarrhea D003967 32 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Stomach Diseases D013272 7 associated lipids
Inflammation D007249 119 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Body Weight D001835 333 associated lipids
Edema D004487 152 associated lipids
Hepatic Encephalopathy D006501 9 associated lipids
Liver Cirrhosis, Experimental D008106 36 associated lipids
Hypothyroidism D007037 32 associated lipids
Kidney Diseases D007674 29 associated lipids
Glioma D005910 112 associated lipids
Metabolism, Inborn Errors D008661 46 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Obesity D009765 29 associated lipids
Hemorrhage D006470 15 associated lipids
Malocclusion D008310 3 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with octanoic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with octanoic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with octanoic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with octanoic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with octanoic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with octanoic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with octanoic acid

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Authors Title Published Journal PubMed Link
Balaraman E et al. Catalytic transformation of alcohols to carboxylic acid salts and H2 using water as the oxygen atom source. 2013 Nat Chem pmid:23344447
Liu P et al. Membrane stress caused by octanoic acid in Saccharomyces cerevisiae. 2013 Appl. Microbiol. Biotechnol. pmid:23435986
Oiso S et al. Establishment of a gastric cell-based assay system for exploring inhibitors of octanoylated ghrelin production. 2013 J Biomol Screen pmid:23704134
Lim CH et al. Effect of DA-9701 on gastric emptying in a mouse model: assessment by ¹³C-octanoic acid breath test. 2013 World J. Gastroenterol. pmid:23885150
Eder M et al. Pharmacokinetic properties of peptidic radiopharmaceuticals: reduced uptake of (EH)3-conjugates in important organs. 2013 J. Nucl. Med. pmid:23804326
Frauches TS et al. Bothropic antivenom based on monoclonal antibodies, is it possible? 2013 Toxicon pmid:23732123
Leonard PH et al. Variability in protein quality used for embryo culture: embryotoxicity of the stabilizer octanoic acid. 2013 Fertil. Steril. pmid:23602317
Coenen MJ et al. Polymorphism in porphyrin monolayers: the relation between adsorption configuration and molecular conformation. 2013 Phys Chem Chem Phys pmid:23620134
Bernardino K and de Moura AF Aggregation thermodynamics of sodium octanoate micelles studied by means of molecular dynamics simulations. 2013 J Phys Chem B pmid:23697593
Roda A et al. Non-invasive panel tests for gastrointestinal motility monitoring within the MARS-500 Project. 2013 World J. Gastroenterol. pmid:23599647
Morrill KM et al. Estimate of serum immunoglobulin G concentration using refractometry with or without caprylic acid fractionation. 2013 J. Dairy Sci. pmid:23664346
Fonseca CR et al. Storage of refrigerated raw goat milk affecting the quality of whole milk powder. 2013 J. Dairy Sci. pmid:23664351
Costello PJ et al. Synthesis of fruity ethyl esters by acyl coenzyme A: alcohol acyltransferase and reverse esterase activities in Oenococcus oeni and Lactobacillus plantarum. 2013 J. Appl. Microbiol. pmid:23216623
Brun AC et al. Nissen fundoplication in children with cerebral palsy: influence on rate of gastric emptying and postprandial symptoms in relation to protein source in caloric liquid meals. 2013 Clin Nutr pmid:23196118
Suzuki S et al. Characterization of actions of octanoate on porcine preadipocytes and adipocytes differentiated in vitro. 2013 Biochem. Biophys. Res. Commun. pmid:23376076
Hulankova R et al. Combined antimicrobial effect of oregano essential oil and caprylic acid in minced beef. 2013 Meat Sci. pmid:23743028
Guo H et al. Influences of hydrocarbon linkers on the receptor binding affinities of gonadotropin-releasing hormone peptides. 2013 Bioorg. Med. Chem. Lett. pmid:24018188
Harmancey R et al. Decreased long-chain fatty acid oxidation impairs postischemic recovery of the insulin-resistant rat heart. 2013 FASEB J. pmid:23825227
Shilling M et al. Antimicrobial effects of virgin coconut oil and its medium-chain fatty acids on Clostridium difficile. 2013 J Med Food pmid:24328700
Hungate EA et al. A locus in Drosophila sechellia affecting tolerance of a host plant toxin. 2013 Genetics pmid:24037270