octanoic acid

octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.

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Introduction

To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with octanoic acid?

octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with octanoic acid

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Diarrhea D003967 32 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Stomach Diseases D013272 7 associated lipids
Inflammation D007249 119 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Body Weight D001835 333 associated lipids
Edema D004487 152 associated lipids
Hepatic Encephalopathy D006501 9 associated lipids
Liver Cirrhosis, Experimental D008106 36 associated lipids
Hypothyroidism D007037 32 associated lipids
Kidney Diseases D007674 29 associated lipids
Glioma D005910 112 associated lipids
Metabolism, Inborn Errors D008661 46 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Obesity D009765 29 associated lipids
Hemorrhage D006470 15 associated lipids
Malocclusion D008310 3 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with octanoic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with octanoic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with octanoic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with octanoic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with octanoic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with octanoic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with octanoic acid

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Authors Title Published Journal PubMed Link
Morrill KM et al. Estimate of serum immunoglobulin G concentration using refractometry with or without caprylic acid fractionation. 2013 J. Dairy Sci. pmid:23664346
Fonseca CR et al. Storage of refrigerated raw goat milk affecting the quality of whole milk powder. 2013 J. Dairy Sci. pmid:23664351
Shilling M et al. Antimicrobial effects of virgin coconut oil and its medium-chain fatty acids on Clostridium difficile. 2013 J Med Food pmid:24328700
Zimmermann S et al. Screening and HPLC-Based Activity Profiling for New Antiprotozoal Leads from European Plants. 2012 Jan-Mar Sci Pharm pmid:22396915
Morais V and Massaldi H A model mechanism for protein precipitation by caprylic acid: application to plasma purification. 2012 Jan-Feb Biotechnol. Appl. Biochem. pmid:22332745
Ryu JK and Yoo SD Preparation and evaluation of bicyclol microemulsions for enhanced oral bioavailability. 2012 Drug Dev Ind Pharm pmid:22283588
Maricic MJ Oral calcitonin. 2012 Curr Osteoporos Rep pmid:22281725
Solano S et al. Low pH formulation of whole IgG antivenom: impact on quality, safety, neutralizing potency and viral inactivation. 2012 Biologicals pmid:22266304
Cordes AA et al. Selective domain stabilization as a strategy to reduce fusion protein aggregation. 2012 J Pharm Sci pmid:22234888
Can Güven S and Laska M Olfactory sensitivity and odor structure-activity relationships for aliphatic carboxylic acids in CD-1 mice. 2012 PLoS ONE pmid:22479594
Librán-Pérez M et al. Evidence of a metabolic fatty acid-sensing system in the hypothalamus and Brockmann bodies of rainbow trout: implications in food intake regulation. 2012 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:22496361
Zhang JH et al. High-throughput screening of B factor saturation mutated Rhizomucor miehei lipase thermostability based on synthetic reaction. 2012 Enzyme Microb. Technol. pmid:22500900
Nahab FB et al. Octanoic acid suppresses harmaline-induced tremor in mouse model of essential tremor. 2012 Neurotherapeutics pmid:22454323
Ogawa N et al. Intestinal fatty acid infusion modulates food preference as well as calorie intake via the vagal nerve and midbrain-hypothalamic neural pathways in rats. 2012 Metab. Clin. Exp. pmid:22445513
Li RL et al. Profound hypoglycemia in starved, ghrelin-deficient mice is caused by decreased gluconeogenesis and reversed by lactate or fatty acids. 2012 J. Biol. Chem. pmid:22474325
Yamada M et al. A medium-chain fatty acid as an alternative energy source in mouse preimplantation development. 2012 Sci Rep pmid:23226596
Nóbrega AC et al. Dyspeptic symptoms and delayed gastric emptying of solids in patients with inactive Crohn's disease. 2012 BMC Gastroenterol pmid:23216812
Chang P et al. The antiepileptic drug valproic acid and other medium-chain fatty acids acutely reduce phosphoinositide levels independently of inositol in Dictyostelium. 2012 Dis Model Mech pmid:21876211
Prajapati HN et al. A comparative evaluation of mono-, di- and triglyceride of medium chain fatty acids by lipid/surfactant/water phase diagram, solubility determination and dispersion testing for application in pharmaceutical dosage form development. 2012 Pharm. Res. pmid:21861203
Mohan A et al. Role of peroxyacetic acid, octanoic acid, malic acid, and potassium lactate on the microbiological and instrumental color characteristics of ground beef. 2012 J. Food Sci. pmid:22352902