octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.
To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with octanoic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Crane J et al. | Triacylglycerols determine the unusual storage physiology of Cuphea seed. | 2003 | Planta | pmid:12743824 |
Trejo SR et al. | Evaluation of virus and prion reduction in a new intravenous immunoglobulin manufacturing process. | 2003 | Vox Sang. | pmid:12670366 |
Lebing W et al. | Properties of a new intravenous immunoglobulin (IGIV-C, 10%) produced by virus inactivation with caprylate and column chromatography. | 2003 | Vox Sang. | pmid:12670368 |
Ballow M et al. | Pharmacokinetics and tolerability of a new intravenous immunoglobulin preparation, IGIV-C, 10% (Gamunex, 10%). | 2003 | Vox Sang. | pmid:12670369 |
van de Casteele M et al. | Oxidative breakdown of octanoic acid is maintained in patients with cirrhosis despite advanced disease. | 2003 | Neurogastroenterol. Motil. | pmid:12680910 |
Sutton DG et al. | Validation of the 13C-octanoic acid breath test for measurement of equine gastric emptying rate of solids using radioscintigraphy. | 2003 | Equine Vet. J. | pmid:12553459 |
Heurtault B et al. | The influence of lipid nanocapsule composition on their size distribution. | 2003 | Eur J Pharm Sci | pmid:12554073 |
Gimeno RE et al. | Characterization of a heart-specific fatty acid transport protein. | 2003 | J. Biol. Chem. | pmid:12556534 |
Nowak-Thompson B et al. | 2,5-dialkylresorcinol biosynthesis in Pseudomonas aurantiaca: novel head-to-head condensation of two fatty acid-derived precursors. | 2003 | J. Bacteriol. | pmid:12533461 |
Wyse CA et al. | A comparison of the rate of recovery of 13CO2 in exhaled breath with 2H in body water following ingestion of [2H/13C]octanoic acid in a dog. | 2003 | Res. Vet. Sci. | pmid:12589736 |
Jordan SW and Cronan JE | The Escherichia coli lipB gene encodes lipoyl (octanoyl)-acyl carrier protein:protein transferase. | 2003 | J. Bacteriol. | pmid:12591875 |
Wu HA et al. | Rapid differentiation between short-chain-length and medium-chain-length polyhydroxyalkanoate-accumulating bacteria with spectrofluorometry. | 2003 | J. Microbiol. Methods | pmid:12609733 |
Walton ME et al. | Relative rates of anaplerotic flux in rested and contracted rat skeletal muscle measured by 13C NMR spectroscopy. | 2003 | J. Physiol. (Lond.) | pmid:12611923 |
Jones PM et al. | Accumulation of 3-hydroxy-fatty acids in the culture medium of long-chain L-3-hydroxyacyl CoA dehydrogenase (LCHAD) and mitochondrial trifunctional protein-deficient skin fibroblasts: implications for medium chain triglyceride dietary treatment of LCHAD deficiency. | 2003 | Pediatr. Res. | pmid:12621125 |
Wang ZY and Zhang Q | [Study on pulmonary delivery of peptide drugs in rats: effects of absorption enhancers on cellular membrane fluidity]. | 2003 | Yao Xue Xue Bao | pmid:15040095 |
Massillon D et al. | Regulation of glucose-6-phosphatase gene expression in cultured hepatocytes and H4IIE cells by short-chain fatty acids: role of hepatic nuclear factor-4alpha. | 2003 | J. Biol. Chem. | pmid:12915406 |
Mori S et al. | Rat organic anion transporter 3 (rOAT3) is responsible for brain-to-blood efflux of homovanillic acid at the abluminal membrane of brain capillary endothelial cells. | 2003 | J. Cereb. Blood Flow Metab. | pmid:12679720 |
Iwahashi H et al. | The formation of the 7-carboxyheptyl radical from 13-hydroperoxy-9,11-octadecadienoic acid catalyzed by hemoglobin and myoglobin under anaerobic conditions. | 2003 | J. Biochem. | pmid:12801921 |
Margolles Cabrales I et al. | Influence of Fatty acids on foaming properties of cider. | 2003 | J. Agric. Food Chem. | pmid:14518961 |
Miele L et al. | Hepatic mitochondrial beta-oxidation in patients with nonalcoholic steatohepatitis assessed by 13C-octanoate breath test. | 2003 | Am. J. Gastroenterol. | pmid:14572600 |
Chew CG et al. | Simultaneous 13C/14C dual isotope breath test measurement of gastric emptying of solid and liquid in normal subjects and patients: comparison with scintigraphy. | 2003 | Nucl Med Rev Cent East Eur | pmid:14600930 |
Osborn-Barnes HT and Akoh CC | Copper-catalyzed oxidation of a structured lipid-based emulsion containing alpha-tocopherol and citric acid: influence of pH and NaCl. | 2003 | J. Agric. Food Chem. | pmid:14582985 |
Osborn-Barnes HT and Akoh CC | Effects of alpha-tocopherol, beta-carotene, and soy isoflavones on lipid oxidation of structured lipid-based emulsions. | 2003 | J. Agric. Food Chem. | pmid:14582986 |
Sakaki K and Itoh N | Optical resolution of racemic 2-hydroxy octanoic acid by lipase-catalyzed hydrolysis in a biphasic membrane reactor. | 2003 | Biotechnol. Lett. | pmid:14584912 |
Sarnelli G et al. | Symptom patterns and pathophysiological mechanisms in dyspeptic patients with and without Helicobacter pylori. | 2003 | Dig. Dis. Sci. | pmid:14714606 |
Lai CY and Cronan JE | Beta-ketoacyl-acyl carrier protein synthase III (FabH) is essential for bacterial fatty acid synthesis. | 2003 | J. Biol. Chem. | pmid:14523010 |
Wang Z and Zhang Q | [Study on pulmonary delivery system of salmon calcitonin in rats]. | 2003 | Beijing Da Xue Xue Bao | pmid:12914259 |
Ho TS et al. | Liquid-phase microextraction of hydrophilic drugs by carrier-mediated transport. | 2003 | J Chromatogr A | pmid:12862372 |
Kudo N and Kawashima Y | Toxicity and toxicokinetics of perfluorooctanoic acid in humans and animals. | 2003 | J Toxicol Sci | pmid:12820537 |
Macko T et al. | Elution behavior of polyethylene in polar mobile phases on a non-polar sorbent. | 2003 | J Chromatogr A | pmid:12647822 |
Takenaka T et al. | Fatty acids as an energy source for the operation of axoplasmic transport. | 2003 | Brain Res. | pmid:12711076 |
Pêgo AP et al. | Physical properties of high molecular weight 1,3-trimethylene carbonate and D,L-lactide copolymers. | 2003 | J Mater Sci Mater Med | pmid:15348396 |
Lee SH et al. | Elastic biodegradable poly(glycolide-co-caprolactone) scaffold for tissue engineering. | 2003 | J Biomed Mater Res A | pmid:12833428 |
Zhou S et al. | Biodegradable poly(epsilon-caprolactone)-poly(ethylene glycol) block copolymers: characterization and their use as drug carriers for a controlled delivery system. | 2003 | Biomaterials | pmid:12809785 |
Cai Q et al. | Synthesis and characterization of biodegradable polylactide-grafted dextran and its application as compatilizer. | 2003 | Biomaterials | pmid:12809784 |
Winiarska K et al. | Relationship between gluconeogenesis and glutathione redox state in rabbit kidney-cortex tubules. | 2003 | Metab. Clin. Exp. | pmid:12800101 |
Hamel FG et al. | In vitro inhibition of insulin-degrading enzyme by long-chain fatty acids and their coenzyme A thioesters. | 2003 | Endocrinology | pmid:12746301 |
Iwasaki Y et al. | Reduced adhesion of blood cells to biodegradable polymers by introducing phosphorylcholine moieties. | 2003 | J Biomed Mater Res A | pmid:12734808 |
Theakston RD et al. | Report of a WHO workshop on the standardization and control of antivenoms. | 2003 | Toxicon | pmid:12676433 |
Hara Y et al. | Exposure to fatty acids modulates interferon production by intraepithelial lymphocytes. | 2003 | Immunol. Lett. | pmid:12644315 |
Knight VK et al. | Biotransformation of 3,5-dibromo-4-hydroxybenzonitrile under denitrifying, Fe(III)-reducing, sulfidogenic, and methanogenic conditions. | 2003 | Environ. Toxicol. Chem. | pmid:12627640 |
Nguyen CA et al. | Cell interaction studies of PLA-MePEG nanoparticles. | 2003 | Int J Pharm | pmid:12615412 |
Oettl K et al. | An apparent decrease in cholesterol biosynthesis in peroxisomal-defective Chinese hamster ovary cells is related to impaired mitochondrial oxidation. | 2003 | Biochem. Biophys. Res. Commun. | pmid:12767923 |
Maes BD et al. | Gastric emptying in renal failure patients using the 13C-octanoic acid breath test: facts and artifacts. | 2002 Nov-Dec | Perit Dial Int | pmid:12556082 |
Green PR et al. | Formation of short chain length/medium chain length polyhydroxyalkanoate copolymers by fatty acid beta-oxidation inhibited Ralstonia eutropha. | 2002 Jan-Feb | Biomacromolecules | pmid:11866575 |
Schoonjans R et al. | The 13C-octanoic acid breath test: validation of a new noninvasive method of measuring gastric emptying in rats. | 2002 | Neurogastroenterol. Motil. | pmid:12061914 |
Bender JL et al. | Site-isolated luminescent europium complexes with polyester macroligands: metal-centered heteroarm stars and nanoscale assemblies with labile block junctions. | 2002 | J. Am. Chem. Soc. | pmid:12121083 |
Giannakou SA et al. | In vitro evaluation of nimodipine permeation through human epidermis using response surface methodology. | 2002 | Int J Pharm | pmid:12086718 |
GarcÃa-Villafranca J and Castro J | Effects of 5-iodotubercidin on hepatic fatty acid metabolism mediated by the inhibition of acetyl-CoA carboxylase. | 2002 | Biochem. Pharmacol. | pmid:12093476 |
Slater C et al. | Bulk and compound specific analysis of stool lipid confirm that the "missing" 13C in the mixed triacylglycerol breath test is not in the stool. | 2002 | Food Nutr Bull | pmid:12362811 |
Tachibana S et al. | Octanoate inhibits very low-density lipoprotein secretion in primary cultures of chicken hepatocytes. | 2002 | Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. | pmid:12044771 |
Diard S et al. | Accumulation of poly(3-hydroxybutyrate) from octanoate in different pseudomonas belonging to the rRNA homology group I. | 2002 | Syst. Appl. Microbiol. | pmid:12353870 |
Chuang VT and Otagiri M | How do fatty acids cause allosteric binding of drugs to human serum albumin? | 2002 | Pharm. Res. | pmid:12425462 |
Fomuso LB et al. | Metal-catalyzed oxidation of a structured lipid model emulsion. | 2002 | J. Agric. Food Chem. | pmid:12428969 |
Giesy JG et al. | Effect of dose of calcium salts of conjugated linoleic acid (CLA) on percentage and fatty acid content of milk fat in midlactation holstein cows. | 2002 | J. Dairy Sci. | pmid:12214995 |
Torres-Guzmán R et al. | Substrate specificity of penicillin acylase from Streptomyces lavendulae. | 2002 | Biochem. Biophys. Res. Commun. | pmid:11855830 |
Slater C et al. | Analysis of 13C-mixed triacylglycerol in stool by bulk (EA-IRMS) and compound specific (GC/MS) methods. | 2002 | Isotopes Environ Health Stud | pmid:12219984 |
Kimura M et al. | A sensitive and simplified method to analyze free fatty acids in children with mitochondrial beta oxidation disorders using gas chromatography/mass spectrometry and dried blood spots. | 2002 | Clin. Chim. Acta | pmid:11750281 |
Abdel-Hamid ME et al. | Stability study of the anticonvulsant enaminone (E118) using HPLC and LC-MS. | 2002 | J Pharm Biomed Anal | pmid:11682230 |
Gwak HS et al. | Effect of vehicles and enhancers on the in vitro permeation of melatonin through hairless mouse skin. | 2002 | Arch. Pharm. Res. | pmid:12135116 |
Sun CQ et al. | The antimicrobial properties of milkfat after partial hydrolysis by calf pregastric lipase. | 2002 | Chem. Biol. Interact. | pmid:12076524 |
Demizieux L et al. | Conjugated linoleic acid isomers in mitochondria: evidence for an alteration of fatty acid oxidation. | 2002 | J. Lipid Res. | pmid:12454273 |
Seddik SS et al. | Improved purification and yield of the Egyptian snake Cerastes cerastes antitoxin by the use of caprylic acid. | 2002 | J Nat Toxins | pmid:12503875 |
Jelen HH et al. | Influence of octanoic acid addition to medium on some volatile compounds and PR-toxin biosynthesis by Penicillium roqueforti. | 2002 | Lett. Appl. Microbiol. | pmid:12081547 |
Patel S and Shibamoto T | Effect of different strains of Saccharomyces cerevisiae on production of volatiles in Napa Gamay wine and Petite Sirah wine. | 2002 | J. Agric. Food Chem. | pmid:12236692 |
Duque-Beltrán S et al. | Detection of Giardia duodenalis antigen in human fecal eluates by enzyme-linked immunosorbent assay using polyclonal antibodies. | 2002 | Mem. Inst. Oswaldo Cruz | pmid:12563485 |
McLay JC et al. | Inhibition of bacterial foodborne pathogens by the lactoperoxidase system in combination with monolaurin. | 2002 | Int. J. Food Microbiol. | pmid:11883670 |
Buclin T et al. | Bioavailability and biological efficacy of a new oral formulation of salmon calcitonin in healthy volunteers. | 2002 | J. Bone Miner. Res. | pmid:12162502 |
Spildo K and Blokhus AM | Adsorption from the organic phase in the octanoic acid-octylamine-silica system. | 2002 | J Colloid Interface Sci | pmid:16290813 |
Banks WA et al. | Extent and direction of ghrelin transport across the blood-brain barrier is determined by its unique primary structure. | 2002 | J. Pharmacol. Exp. Ther. | pmid:12130749 |
Leite-Moreira AF et al. | Modulation of myocardial function by pyruvate. | 2002 | Rev Port Cardiol | pmid:12090129 |
Dutta P and Fendler JH | Preparation of cadmium sulfide nanoparticles in self-reproducing reversed micelles. | 2002 | J Colloid Interface Sci | pmid:16290439 |
Jørgensen JR et al. | Absorption and metabolism of octanoate by the rat colon in vivo: concentration dependency and influence of alternative fuels. | 2002 | Gut | pmid:12077096 |
Hang X et al. | PCR cloning of polyhydroxyalkanoate biosynthesis genes from Burkholderia caryophylli and their functional expression in recombinant Escherichia coli. | 2002 | FEMS Microbiol. Lett. | pmid:12023076 |
Ahmad R and Magan N | Microfloral contamination and hydrolytic enzyme differences between monsooned and non-monsooned coffees. | 2002 | Lett. Appl. Microbiol. | pmid:11940159 |
Kawaguchi T et al. | Mechanism for fatty acid "sparing" effect on glucose-induced transcription: regulation of carbohydrate-responsive element-binding protein by AMP-activated protein kinase. | 2002 | J. Biol. Chem. | pmid:11724780 |
Okamoto K et al. | Production of gamma-lactones by the brown-rot basidiomycete Piptoporus soloniensis. | 2002 | J. Biosci. Bioeng. | pmid:16233291 |
Sugihara A et al. | Purification and characterization of a novel cholesterol esterase from Pseudomonas aeruginosa, with its application to cleaning lipid-stained contact lenses. | 2002 | Biosci. Biotechnol. Biochem. | pmid:12506971 |
Apel CL et al. | Self-assembled vesicles of monocarboxylic acids and alcohols: conditions for stability and for the encapsulation of biopolymers. | 2002 | Biochim. Biophys. Acta | pmid:11825583 |
Jong-Yeon K et al. | Long- and medium-chain fatty acid oxidation is increased in exercise-trained human skeletal muscle. | 2002 | Metab. Clin. Exp. | pmid:11912554 |
Pera P et al. | Influence of mastication on gastric emptying. | 2002 | J. Dent. Res. | pmid:11876271 |
Robinson MK | Population differences in acute skin irritation responses. Race, sex, age, sensitive skin and repeat subject comparisons. | 2002 | Contact Derm. | pmid:11918601 |
Bluck LJ et al. | Measurement of gastric emptying in man using deuterated octanoic acid. | 2002 | Rapid Commun. Mass Spectrom. | pmid:11754258 |
Turcotte LP et al. | High carbohydrate availability increases LCFA uptake and decreases LCFA oxidation in perfused muscle. | 2002 | Am. J. Physiol. Endocrinol. Metab. | pmid:11739099 |
Iwahashi H et al. | Cytochrome c catalyses the formation of pentyl radical and octanoic acid radical from linoleic acid hydroperoxide. | 2002 | Biochem. J. | pmid:11742529 |
Guan Z | Identification and localization of the fatty acid modification in ghrelin by electron capture dissociation. | 2002 | J. Am. Soc. Mass Spectrom. | pmid:12484464 |
Kojima M and Kangawa K | Ghrelin, an orexigenic signaling molecule from the gastrointestinal tract. | 2002 | Curr Opin Pharmacol | pmid:12482728 |
Coort SL et al. | Sulfo-N-succinimidyl esters of long chain fatty acids specifically inhibit fatty acid translocase (FAT/CD36)-mediated cellular fatty acid uptake. | 2002 | Mol. Cell. Biochem. | pmid:12479588 |
Ward DS et al. | Pharmacodynamics and pharmacokinetics of propofol in a medium-chain triglyceride emulsion. | 2002 | Anesthesiology | pmid:12459665 |
Angelos MG et al. | Glucose, insulin and potassium (GIK) during reperfusion mediates improved myocardial bioenergetics. | 2002 | Resuscitation | pmid:12458070 |
Kuge Y et al. | In vitro uptake of [1-14C]Octanoate in brain slices of rats: basic studies for assessing [1-11C]Octanoate as a PET tracer of glial functions. | 2002 | Nucl. Med. Biol. | pmid:11929699 |
Bianchi M and Capurso L | Effects of guar gum, ispaghula and microcrystalline cellulose on abdominal symptoms, gastric emptying, orocaecal transit time and gas production in healthy volunteers. | 2002 | Dig Liver Dis | pmid:12408456 |
Hoshimoto A et al. | Caprylic acid and medium-chain triglycerides inhibit IL-8 gene transcription in Caco-2 cells: comparison with the potent histone deacetylase inhibitor trichostatin A. | 2002 | Br. J. Pharmacol. | pmid:12010777 |
Olivier JC et al. | Synthesis of pegylated immunonanoparticles. | 2002 | Pharm. Res. | pmid:12240939 |
Robertson MD et al. | Acute ingestion of a meal rich in n-3 polyunsaturated fatty acids results in rapid gastric emptying in humans. | 2002 | Am. J. Clin. Nutr. | pmid:12081840 |
Jagielski AK et al. | Purinergic regulation of glucose and glutamine synthesis in isolated rabbit kidney-cortex tubules. | 2002 | Arch. Biochem. Biophys. | pmid:12147256 |
Watanabe Y et al. | Suppressive effect of saturated acyl L-ascorbate on the oxidation of linoleic acid encapsulated with maltodextrin or gum arabic by spray-drying. | 2002 | J. Agric. Food Chem. | pmid:12083870 |
Chassard D et al. | Effects of subhypnotic doses of propofol on gastric emptying in volunteers. | 2002 | Anesthesiology | pmid:12131109 |
Babu E et al. | Role of human organic anion transporter 4 in the transport of ochratoxin A. | 2002 | Biochim. Biophys. Acta | pmid:12063169 |
Dichtelmüller H et al. | Inactivation of lipid enveloped viruses by octanoic Acid treatment of immunoglobulin solution. | 2002 | Biologicals | pmid:12127315 |